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Where hearing starts: the development of the mammalian cochleaThe Stereociliary Paracrystal Is a Dynamic Cytoskeletal Scaffold In VivoEps8 regulates hair bundle length and functional maturation of mammalian auditory hair cells.Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like.Structural basis for the slow dynamics of the actin filament pointed endRegulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8Mutations in Grxcr1 are the basis for inner ear dysfunction in the pirouette mouseMyosin IIIB uses an actin-binding motif in its espin-1 cargo to reach the tips of actin protrusionsAn alteration in ELMOD3, an Arl2 GTPase-activating protein, is associated with hearing impairment in humansMyosin VIIa and sans localization at stereocilia upper tip-link density implicates these Usher syndrome proteins in mechanotransductionFCHSD1 and FCHSD2 are expressed in hair cell stereocilia and cuticular plate and regulate actin polymerization in vitro.Actin in hair cells and hearing loss.Mutations of the mouse ELMO domain containing 1 gene (Elmod1) link small GTPase signaling to actin cytoskeleton dynamics in hair cell stereocilia.Linking genes underlying deafness to hair-bundle development and function.Physiopathological function of hematoside (GM3 ganglioside).Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia.Harmonin mutations cause mechanotransduction defects in cochlear hair cells.Myosin IIIa boosts elongation of stereocilia by transporting espin 1 to the plus ends of actin filaments.Progressive hearing loss and gradual deterioration of sensory hair bundles in the ears of mice lacking the actin-binding protein Eps8L2.Design Principles of Length Control of Cytoskeletal Structures.Actin cross-linkers and the shape of stereociliaNuclear size is regulated by importin α and Ntf2 in Xenopus.Myosin motor function: the ins and outs of actin-based membrane protrusions.Nonsense mutations in SMPX, encoding a protein responsive to physical force, result in X-chromosomal hearing loss.Coupling of the mechanotransduction machinery and F-actin polymerization in the cochlear hair bundlesPerception of sound and gravity by TMC1 and TMC2Whirlin interacts with espin and modulates its actin-regulatory function: an insight into the mechanism of Usher syndrome type II.Theory of active transport in filopodia and stereocilia.The 133-kDa N-terminal domain enables myosin 15 to maintain mechanotransducing stereocilia and is essential for hearingCompetition and compensation: dissecting the biophysical and functional differences between the class 3 myosin paralogs, myosins 3a and 3b.Protein localization by actin treadmilling and molecular motors regulates stereocilia shape and treadmilling rate.Changes in ADF/destrin expression in the development of hair cells following Atoh1-induced ectopic regeneration.Filopodia-like actin cables position nuclei in association with perinuclear actin in Drosophila nurse cells.Myosin 3A kinase activity is regulated by phosphorylation of the kinase domain activation loop.Glycoconjugates in the mammalian auditory system.A two-segment model for thin filament architecture in skeletal muscle.Pejvakin, a Candidate Stereociliary Rootlet Protein, Regulates Hair Cell Function in a Cell-Autonomous Manner.Titin and Nebulin in Thick and Thin Filament Length Regulation.Alignment of nematic and bundled semiflexible polymers in cell-sized confinement.The actin-binding proteins eps8 and gelsolin have complementary roles in regulating the growth and stability of mechanosensory hair bundles of mammalian cochlear outer hair cells.
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Dynamic length regulation of sensory stereocilia
@ast
Dynamic length regulation of sensory stereocilia
@en
Dynamic length regulation of sensory stereocilia
@nl
type
label
Dynamic length regulation of sensory stereocilia
@ast
Dynamic length regulation of sensory stereocilia
@en
Dynamic length regulation of sensory stereocilia
@nl
prefLabel
Dynamic length regulation of sensory stereocilia
@ast
Dynamic length regulation of sensory stereocilia
@en
Dynamic length regulation of sensory stereocilia
@nl
P2860
P1476
Dynamic length regulation of sensory stereocilia
@en
P2093
Bechara Kachar
P2860
P304
P356
10.1016/J.SEMCDB.2008.07.006
P407
P577
2008-12-01T00:00:00Z