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Defective thrombus formation in mice lacking coagulation factor XII

Defective thrombus formation in mice lacking coagulation factor XII

http://www.wikidata.org/entity/Q24646366

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Thrombus formation in vivo.Factor XII: what does it contribute to our understanding of the physiology and pathophysiology of hemostasis & thrombosis Platelet polyphosphates are proinflammatory and procoagulant mediators in vivo Increased activity of coagulation factor XII (Hageman factor) causes hereditary angioedema type III An EF hand mutation in Stim1 causes premature platelet activation and bleeding in mice The factor XIIa blocking antibody 3F7: a safe anticoagulant with anti-inflammatory activities Future prospects for contact factors as therapeutic targets Next-generation antithrombotics in ischemic stroke: preclinical perspective on 'bleeding-free antithrombosis'Factor XI as a target for antithrombotic therapy PAMPs and DAMPs as triggers for DIC Coagulation and the vessel wall in pulmonary embolism Sex differences in stroke: the contribution of coagulation Factor XI and contact activation as targets for antithrombotic therapy Complement-Coagulation Cross-Talk: A Potential Mediator of the Physiological Activation of Complement by Low pH Quantification of the Blood Platelet Reactivity in the ADP-Induced Model of Non-Lethal Pulmonary Thromboembolism in Mice with the Use of Laser Doppler Flowmetry The role of saliva in tick feeding The structure of the FnI-EGF-like tandem domain of coagulation factor XII solved using SIRAS Novel Family of Insect Salivary Inhibitors Blocks Contact Pathway Activation by Binding to Polyphosphate, Heparin, and Dextran Sulfate The Kazal-type inhibitors infestins 1 and 4 differ in specificity but are similar in three-dimensional structure A Novel Antithrombotic Mechanism Mediated by the Receptors of the Kallikrein/Kinin and Renin-Angiotensin Systems Anithrombotic prevention in vascular disease: bases for a new strategy in antithrombotic therapy Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis Murine prolylcarboxypeptidase depletion induces vascular dysfunction with hypertension and faster arterial thrombosis Interference with the host haemostatic system by schistosomes A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo Hageman factor, platelets and polyphosphates: early history and recent connection Extracellular RNA constitutes a natural procoagulant cofactor in blood coagulation.Deletion of murine kininogen gene 1 (mKng1) causes loss of plasma kininogen and delays thrombosis The complex puzzle underlying the pathophysiology of acute coronary syndromes: from molecular basis to clinical manifestations.Sequence variation and genetic evolution at the human F12 locus: mapping quantitative trait nucleotides that influence FXII plasma levels.Interactions outside the proteinase-binding loop contribute significantly to the inhibition of activated coagulation factor XII by its canonical inhibitor from corn.Nitrophorin 2, a factor IX(a)-directed anticoagulant, inhibits arterial thrombosis without impairing haemostasis Selection and characterization of a DNA aptamer inhibiting coagulation factor XIa.Factor XII as a Risk Marker for Hemorrhagic Stroke: A Prospective Cohort Study.A novel missense mutation in the factor XII gene in a litter of cats with factor XII deficiency.Transforming growth factor-β1 induces expression of human coagulation factor XII via Smad3 and JNK signaling pathways in human lung fibroblasts.Novel hemostatic factor levels and risk of ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) Study.A history of late and very late stent thrombosis is not associated with increased activation of the contact system, a case control study.Activated factor V is a cofactor for the activation of factor XI by thrombin in plasma.Factor XII stimulates ERK1/2 and Akt through uPAR, integrins, and the EGFR to initiate angiogenesis.

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P2860

Defective thrombus formation in mice lacking coagulation factor XII

http://www.wikidata.org/entity/Q24646366

description

2005 nî lūn-bûn

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2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2005 թվականի հուլիսին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Defective thrombus formation in mice lacking coagulation factor XII

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Defective thrombus formation in mice lacking coagulation factor XII

@en

Defective thrombus formation in mice lacking coagulation factor XII

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type

label

Defective thrombus formation in mice lacking coagulation factor XII

@ast

Defective thrombus formation in mice lacking coagulation factor XII

@en

Defective thrombus formation in mice lacking coagulation factor XII

@nl

prefLabel

Defective thrombus formation in mice lacking coagulation factor XII

@ast

Defective thrombus formation in mice lacking coagulation factor XII

@en

Defective thrombus formation in mice lacking coagulation factor XII

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Journal of Experimental Medicine

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Defective thrombus formation in mice lacking coagulation factor XII

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P2093

Bernhard Nieswandt

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David Gailani

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Hans-Ulrich Pauer

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Kai Schuh

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Miroslava Pozgajová

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Peter Burfeind

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Sabine Grüner

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Thomas Renné

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P2860

A patient with platelets deficient in glycoprotein VI that lack both collagen-induced aggregation and adhesion

Exposure of platelet membrane phosphatidylserine regulates blood coagulation

Platelet-collagen interaction: is GPVI the central receptor?

Role of tissue factor in hemostasis, thrombosis, and vascular development

Studies of a mechanism inhibiting the initiation of the extrinsic pathway of coagulation

Mice lacking factor VII develop normally but suffer fatal perinatal bleeding

Targeted deletion of murine coagulation factor XII gene-a model for contact phase activation in vivo

A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis

The dynamics of thrombin formation

Plasma fibronectin promotes thrombus growth and stability in injured arterioles.

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10.1084/JEM.20050664

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16009717

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2213000

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