Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging - Test2 - elhamkhani - TriplyDB

Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging

Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging

http://www.wikidata.org/entity/Q24646862

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Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression T cell replicative senescence in human aging Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan Defining the toxicology of aging Accelerated telomere attrition is associated with relative household income, diet and inflammation in the pSoBid cohort Effect of cytotoxic chemotherapy on markers of molecular age in patients with breast cancer.Lifestyle impacts on the aging-associated expression of biomarkers of DNA damage and telomere dysfunction in human blood Expression of linear and novel circular forms of an INK4/ARF-associated non-coding RNA correlates with atherosclerosis risk.microRNA expression patterns reveal differential expression of target genes with age.Translational research in immune senescence: assessing the relevance of current models.Total body irradiation causes long-term mouse BM injury via induction of HSC premature senescence in an Ink4a- and Arf-independent manner.Ionizing radiation and aging: rejuvenating an old idea.Senescent cells: a novel therapeutic target for aging and age-related diseases Is HIV a model of accelerated or accentuated aging?Molecular and phenotypic biomarkers of aging Transcriptomic profiles of aging in naïve and memory CD4+ cells from mice Saturated fatty acid metabolism is key link between cell division, cancer, and senescence in cellular and whole organism aging Impact papers on aging in 2009.Ionizing radiation-induced long-term expression of senescence markers in mice is independent of p53 and immune status.Four faces of cellular senescence.Cellular senescence: a link between cancer and age-related degenerative disease?High expression of p16INK4a and low expression of Bmi1 are associated with endothelial cellular senescence in the human cornea.The molecular balancing act of p16(INK4a) in cancer and aging.INK4 locus of the tumor-resistant rodent, the naked mole rat, expresses a functional p15/p16 hybrid isoform Aging, cellular senescence, and cancer Monitoring tumorigenesis and senescence in vivo with a p16(INK4a)-luciferase model.Circulating MicroRNAs as easy-to-measure aging biomarkers in older breast cancer patients: correlation with chronological age but not with fitness/frailty status.p16INK4a reporter mice reveal age-promoting effects of environmental toxicants Exercise attenuates the major hallmarks of aging.Association of CDKN2BAS polymorphism rs4977574 with coronary heart disease: a case-control study and a meta-analysis.Up-regulation of leucocytes genes implicated in telomere dysfunction and cellular senescence correlates with depression and anxiety severity scores.Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse.Expansions of NK-like αβT cells with chronologic aging: novel lymphocyte effectors that compensate for functional deficits of conventional NK cells and T cells.Corneal endothelial cells provide evidence of accelerated cellular senescence associated with HIV infection: a case-control study.Senotherapy: growing old and staying young?Expression of p16(INK4a) prevents cancer and promotes aging in lymphocytes.Overexpression of the cell cycle inhibitor p16INK4a promotes a prothrombotic phenotype following vascular injury in mice Comprehensive geriatric assessment in the older cancer patient: coming of age in clinical cancer care.Reversible cell cycle inhibition and premature aging features imposed by conditional expression of p16Ink4a.A p53/ARF-dependent anticancer barrier activates senescence and blocks tumorigenesis without impacting apoptosis

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Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging

http://www.wikidata.org/entity/Q24646862

description

2009 nî lūn-bûn

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2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի օգոստոսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年论文

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name

Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging

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Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging

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Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging

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type

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Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging

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Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging

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Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging

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prefLabel

Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging

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Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging

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Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging

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J.1474-9726.2009.00489.X

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Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging

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Chad Torrice

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Christin E Burd

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Hanna K Sanoff

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Hyunsoon Cho

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Nancy E Thomas

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Norman E Sharpless

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Yan Liu

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P2860

INK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosis

Identification of a mammalian mitochondrial porphyrin transporter

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

A common allele on chromosome 9 associated with coronary heart disease

Genomewide association analysis of coronary artery disease

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network.

The influence of age on T cell generation and TCR diversity

p16INK4a induces an age-dependent decline in islet regenerative potential

Ink4a/Arf expression is a biomarker of aging

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439-48

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3968253

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10.1111/J.1474-9726.2009.00489.X

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Joseph G. Ibrahim

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227732799

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19485966

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