Many LINE1 elements contribute to the transcriptome of human somatic cells - Test2 - elhamkhani - TriplyDB

Many LINE1 elements contribute to the transcriptome of human somatic cells

Many LINE1 elements contribute to the transcriptome of human somatic cells

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Roles for retrotransposon insertions in human disease An expanding universe of the non-coding genome in cancer biology Human transposon tectonics The Landscape of long noncoding RNA classification Activation of individual L1 retrotransposon instances is restricted to cell-type dependent permissive loci Genome-wide target profiling of piggyBac and Tol2 in HEK 293: pros and cons for gene discovery and gene therapy A comprehensive approach to expression of L1 loci.Transition of LINE-1 DNA methylation status and altered expression in first and third trimester placentas.Hypomethylation of intragenic LINE-1 represses transcription in cancer cells through AGO2.A LINE-1 component to human aging: do LINE elements exact a longevity cost for evolutionary advantage?Somatic expression of LINE-1 elements in human tissues.LINE-1 retrotransposons: mediators of somatic variation in neuronal genomes?Intronic L1 retrotransposons and nested genes cause transcriptional interference by inducing intron retention, exonization and cryptic polyadenylation.Exploring the gonad transcriptome of two extreme male pigs with RNA-seq All y'all need to know 'bout retroelements in cancer.Potential for genomic instability associated with retrotranspositionally-incompetent L1 loci.Epigenetic control of retrotransposon expression in human embryonic stem cells.Evolutionary rate of human tissue-specific genes are related with transposable element insertions.Genes associated with the cis-regulatory functions of intragenic LINE-1 elements TE-array--a high throughput tool to study transposon transcription Inter-locus as well as intra-locus heterogeneity in LINE-1 promoter methylation in common human cancers suggests selective demethylation pressure at specific CpGs.Male germline control of transposable elements.Long interspersed nuclear element-1 hypomethylation in cancer: biology and clinical applications.Next-generation sequencing-based detection of germline L1-mediated transductions.Prenatal arsenic exposure and DNA methylation in maternal and umbilical cord blood leukocytes Retroelements versus APOBEC3 family members: No great escape from the magnificent seven Functional constraints on adaptive evolution of protein ubiquitination sites.A tumor-promoting mechanism mediated by retrotransposon-encoded reverse transcriptase is active in human transformed cell lines.An antisense promoter in mouse L1 retrotransposon open reading frame-1 initiates expression of diverse fusion transcripts and limits retrotransposition.Jumping the fine LINE between species: horizontal transfer of transposable elements in animals catalyses genome evolution.Using a systems-based approach to overcome reductionist strategies in the development of diagnostics.URI Regulates KAP1 Phosphorylation and Transcriptional Repression via PP2A Phosphatase in Prostate Cancer Cells.Prediction of genome-wide DNA methylation in repetitive elements Truncated ORF1 proteins can suppress LINE-1 retrotransposition in trans.How do mammalian transposons induce genetic variation? A conceptual framework: the age, structure, allele frequency, and genome context of transposable elements may define their wide-ranging biological impacts.Intronic retroelements: Not just "speed bumps" for RNA polymerase II.A recent L1 insertion within SPEF2 gene is associated with changes in PRLR expression in sow reproductive organs.Selective changes of retroelement expression in human prostate cancer.LINE-1 distribution in six rodent genomes follow a species-specific pattern.Retrotransposons: mobile and mutagenic from conception to death.

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Many LINE1 elements contribute to the transcriptome of human somatic cells

http://www.wikidata.org/entity/Q24647469

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2009 nî lūn-bûn

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Many LINE1 elements contribute to the transcriptome of human somatic cells

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Many LINE1 elements contribute to the transcriptome of human somatic cells

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Many LINE1 elements contribute to the transcriptome of human somatic cells

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Many LINE1 elements contribute to the transcriptome of human somatic cells

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Many LINE1 elements contribute to the transcriptome of human somatic cells

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Many LINE1 elements contribute to the transcriptome of human somatic cells

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Many LINE1 elements contribute to the transcriptome of human somatic cells

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Many LINE1 elements contribute to the transcriptome of human somatic cells

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Many LINE1 elements contribute to the transcriptome of human somatic cells

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Many LINE1 elements contribute to the transcriptome of human somatic cells

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Haig H Kazazian

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Lili Zhang

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Sanjida H Rangwala

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Initial sequencing and analysis of the human genome

LINE retrotransposon RNA is an essential structural and functional epigenetic component of a core neocentromeric chromatin

Members of the SRY family regulate the human LINE retrotransposons

Hot L1s account for the bulk of retrotransposition in the human population

LINE-1 ORF1 protein localizes in stress granules with other RNA-binding proteins, including components of RNA interference RNA-induced silencing complex

Antisense promoter of human L1 retrotransposon drives transcription of adjacent cellular genes

An important role for RUNX3 in human L1 transcription and retrotransposition

The human genome browser at UCSC

BLAT--the BLAST-like alignment tool

Identifying related L1 retrotransposons by analyzing 3' transduced sequences

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