The diverse functions of Krüppel-like factors 4 and 5 in epithelial biology and pathobiology - Test2 - elhamkhani - TriplyDB

The diverse functions of Krüppel-like factors 4 and 5 in epithelial biology and pathobiology

The diverse functions of Krüppel-like factors 4 and 5 in epithelial biology and pathobiology

http://www.wikidata.org/entity/Q24647882

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Krüppel-like factors: three fingers in control The Krüppel-like factor 9 (KLF9) network in HEC-1-A endometrial carcinoma cells suggests the carcinogenic potential of dys-regulated KLF9 expression Mammalian Krüppel-like factors in health and diseases Endothelial Transdifferentiation of Tumor Cells Triggered by the Twist1-Jagged1-KLF4 Axis: Relationship between Cancer Stemness and Angiogenesis Genomic landscape of human papillomavirus-associated cancers The double life of KLF5: Opposing roles in regulation of gene-expression, cellular function, and transformation MiR-7 promotes epithelial cell transformation by targeting the tumor suppressor KLF4 Transgenic and gene knockout mice in gastric cancer research Krüppel-like factor 4 inhibits proliferation by platelet-derived growth factor receptor beta-mediated, not by retinoic acid receptor alpha-mediated, phosphatidylinositol 3-kinase and ERK signaling in vascular smooth muscle cells Cooperative transcriptional activation by Klf4, Meis2, and Pbx1 MicroRNA-449a overexpression, reduced NOTCH1 signals and scarce goblet cells characterize the small intestine of celiac patients Identification of novel small-molecule compounds that inhibit the proproliferative Kruppel-like factor 5 in colorectal cancer cells by high-throughput screening Modeling co-expression across species for complex traits: insights to the difference of human and mouse embryonic stem cells Klf5 Mediates Odontoblastic Differentiation through Regulating Dentin-Specific Extracellular Matrix Gene Expression during Mouse Tooth Development The Transcription Regulator Krüppel-Like Factor 4 and Its Dual Roles of Oncogene in Glioblastoma and Tumor Suppressor in Neuroblastoma.KLF4 Plays an Essential Role in Corneal Epithelial Homeostasis by Promoting Epithelial Cell Fate and Suppressing Epithelial-Mesenchymal Transition.Krüppel-like factor 5 is a crucial mediator of intestinal tumorigenesis in mice harboring combined ApcMin and KRASV12 mutations.KLF4-dependent epigenetic remodeling modulates podocyte phenotypes and attenuates proteinuria Krüppel-like factors compete for promoters and enhancers to fine-tune transcription.Genetic deletion of Klf4 in the mouse intestinal epithelium ameliorates dextran sodium sulfate-induced colitis by modulating the NF-κB pathway inflammatory response The Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs.A small ubiquitin-related modifier-interacting motif functions as the transcriptional activation domain of Krüppel-like factor 4.Klf4 overexpression activates epithelial cytokines and inflammation-mediated esophageal squamous cell cancer in mice.Regulation of corneal epithelial barrier function by Kruppel-like transcription factor 4.Altered intestinal epithelial homeostasis in mice with intestine-specific deletion of the Krüppel-like factor 4 gene.Expression of the tumor suppressor Krüppel-like factor 4 as a prognostic predictor for colon cancer.Klf5 regulates lineage formation in the pre-implantation mouse embryo.Krüppel-like factor 5 protects against murine colitis and activates JAK-STAT signaling in vivo.Krüppel-like factor 4, a tumor suppressor in hepatocellular carcinoma cells reverts epithelial mesenchymal transition by suppressing slug expression.Critical role of Klf5 in regulating gene expression during post-eyelid opening maturation of mouse corneas.Molecular mechanisms for activation of the agouti-related protein and stimulation of appetite.Krüppel-like factor 4 is a radioprotective factor for the intestine following γ-radiation-induced gut injury in mice.Krüppel-like Factor 4 Modulates Development of BMI1(+) Intestinal Stem Cell-Derived Lineage Following γ-Radiation-Induced Gut Injury in Mice.Krüppel-like factor 5 protects against dextran sulfate sodium-induced colonic injury in mice by promoting epithelial repair Helicobacter pylori promotes the expression of Krüppel-like factor 5, a mediator of carcinogenesis, in vitro and in vivo.Krüppel-like factor 5 mediates cellular transformation during oncogenic KRAS-induced intestinal tumorigenesis Regulatable in vivo biotinylation expression system in mouse embryonic stem cells.Different expression patterns and functions of acetylated and unacetylated Klf5 in the proliferation and differentiation of prostatic epithelial cells.Vertebrate intestinal endoderm development.Mouse embryonic fibroblasts null for the Krüppel-like factor 4 gene are genetically unstable.

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The diverse functions of Krüppel-like factors 4 and 5 in epithelial biology and pathobiology

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2007 nî lūn-bûn

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2007 թվականի հունիսին հրատարակված գիտական հոդված

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2007年の論文

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The diverse functions of Krüpp ...... elial biology and pathobiology

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Amr M Ghaleb

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Beth B McConnell

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Mandayam O Nandan

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Vincent W Yang

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P2860

Identification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest

A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cells

Opposing effects of Krüppel-like factor 4 (gut-enriched Krüppel-like factor) and Krüppel-like factor 5 (intestinal-enriched Krüppel-like factor) on the promoter of the Krüppel-like factor 4 gene.

Krüppel-like factors 4 and 5: the yin and yang regulators of cellular proliferation

A gene encoding an intestinal-enriched member of the Krüppel-like factor family expressed in intestinal epithelial cells

A tale of three fingers: the family of mammalian Sp/XKLF transcription factors

Transcriptional profiling of Krüppel-like factor 4 reveals a function in cell cycle regulation and epithelial differentiation

Overexpression of Krüppel-like factor 4 in the human colon cancer cell line RKO leads to reduced tumorigenecity

The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter

Intestinal-enriched Krüppel-like factor (Krüppel-like factor 5) is a positive regulator of cellular proliferation

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549-57

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scholarly article

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1394400

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10.1002/BIES.20581

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6

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29

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6324849

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17508399

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2211634

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