Crystal structures of human alpha-defensins HNP4, HD5, and HD6
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Single, double and quadruple alanine substitutions at oligomeric interfaces identify hydrophobicity as the key determinant of human neutrophil alpha defensin HNP1 functionSometimes it takes two to tango: contributions of dimerization to functions of human α-defensin HNP1 peptideInvariant gly residue is important for α-defensin folding, dimerization, and function: a case study of the human neutrophil α-defensin HNP1Trp-26 imparts functional versatility to human alpha-defensin HNP1Through the looking glass, mechanistic insights from enantiomeric human defensinsStructure-dependent functional properties of human defensin 5Paneth cell α-defensins and enteric microbiota in health and diseasePeptides and Peptidomimetics for Antimicrobial Drug DesignCationic membrane peptides: atomic-level insight of structure-activity relationships from solid-state NMRDetermining the orientation and localization of membrane-bound peptidesAntiviral mechanisms of human defensinsAn intrinsically disordered region of the adenovirus capsid is implicated in neutralization by human alpha defensin 5Toward understanding the cationicity of defensins. Arg and Lys versus their noncoded analogsSynthesis, Structure, and Activities of an Oral Mucosal -Defensin from Rhesus MacaqueSelective arginines are important for the antibacterial activity and host cell interaction of human alpha-defensin 5Resonance Assignment and Three-Dimensional Structure Determination of a Human α-Defensin, HNP-1, by Solid-State NMRNMR Solution Structure and Condition-Dependent Oligomerization of the Antimicrobial Peptide Human Defensin 5Dimerization of Plant Defensin NaD1 Enhances Its Antifungal ActivityFunctional Determinants of Human Enteric -Defensin HD5: CRUCIAL ROLE FOR HYDROPHOBICITY AT DIMER INTERFACEHuman -Defensin 6 Promotes Mucosal Innate Immunity Through Self-Assembled Peptide NanonetsThe intramolecular disulfide-stapled structure of laterosporulin, a class IId bacteriocin, conceals a human defensin-like structural moduleHuman defensin 5 disulfide array mutants: disulfide bond deletion attenuates antibacterial activity against Staphylococcus aureusDiscovery and characterization of a disulfide-locked C(2)-symmetric defensin peptide.Human defensin alpha-1 causes Trypanosoma cruzi membrane pore formation and induces DNA fragmentation, which leads to trypanosome destruction.Different dynamics and pathway of disulfide bonds reduction of two human defensins, a molecular dynamics simulation study.Molecular evolution of the primate α-/θ-defensin multigene family.Variations in the interaction of human defensins with Escherichia coli: Possible implications in bacterial killingHydrophobic determinants of α-defensin bactericidal activity.Insight into the mechanisms of adenovirus capsid disassembly from studies of defensin neutralizationThe membrane-bound structure and topology of a human α-defensin indicate a dimer pore mechanism for membrane disruption.Paneth cell α-defensins in enteric innate immunityStructure and dynamics of cationic membrane peptides and proteins: insights from solid-state NMR.Alpha-defensin-dependent enhancement of enteric viral infection.Molecular basis for self-assembly of a human host-defense peptide that entraps bacterial pathogensComparative genomics and evolution of the alpha-defensin multigene family in primatesArginine-specific mono ADP-ribosylation in vitro of antimicrobial peptides by ADP-ribosylating toxinsInhibition of HIV-1 infection by human α-defensin-5, a natural antimicrobial peptide expressed in the genital and intestinal mucosae.Innate immunity and non-Hodgkin's lymphoma (NHL) related genes in a nested case-control study for gastric cancer risk.The chemistry and biology of theta defensins.Neisseria gonorrhoeae-induced human defensins 5 and 6 increase HIV infectivity: role in enhanced transmission.
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P2860
Crystal structures of human alpha-defensins HNP4, HD5, and HD6
description
2006 nî lūn-bûn
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2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
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2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年學術文章
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name
Crystal structures of human alpha-defensins HNP4, HD5, and HD6
@ast
Crystal structures of human alpha-defensins HNP4, HD5, and HD6
@en
Crystal structures of human alpha-defensins HNP4, HD5, and HD6
@nl
type
label
Crystal structures of human alpha-defensins HNP4, HD5, and HD6
@ast
Crystal structures of human alpha-defensins HNP4, HD5, and HD6
@en
Crystal structures of human alpha-defensins HNP4, HD5, and HD6
@nl
prefLabel
Crystal structures of human alpha-defensins HNP4, HD5, and HD6
@ast
Crystal structures of human alpha-defensins HNP4, HD5, and HD6
@en
Crystal structures of human alpha-defensins HNP4, HD5, and HD6
@nl
P2093
P2860
P921
P356
P1433
P1476
Crystal structures of human alpha-defensins HNP4, HD5, and HD6
@en
P2093
Agnieszka Szyk
Kenneth Tucker
P2860
P304
P356
10.1110/PS.062336606
P407
P577
2006-12-01T00:00:00Z