Broad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family Coronaviridae - Test2 - elhamkhani - TriplyDB

Broad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family Coronaviridae

Broad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family Coronaviridae

http://www.wikidata.org/entity/Q24648487

about

Activity of and effect of subcutaneous treatment with the broad-spectrum antiviral lectin griffithsin in two laboratory rodent models Plant-produced candidate countermeasures against emerging and reemerging infections and bioterror agents Porifera Lectins: Diversity, Physiological Roles and Biotechnological Potential Bulk production of the antiviral lectin griffithsin Monomerization of Viral Entry Inhibitor Griffithsin Elucidates the Relationship between Multivalent Binding to Carbohydrates and anti-HIV Activity Griffithsin: An Antiviral Lectin with Outstanding Therapeutic Potential HIV-1 gp120 as a therapeutic target: navigating a moving labyrinth Pharmacokinetics of the Antiviral Lectin Griffithsin Administered by Different Routes Indicates Multiple Potential Uses Investigation of griffithsin's interactions with human cells confirms its outstanding safety and efficacy profile as a microbicide candidate Pathogenesis and Inhibition of Flaviviruses from a Carbohydrate Perspective A novel and fully scalable Agrobacterium spray-based process for manufacturing cellulases and other cost-sensitive proteins in plants.High mannose-binding lectin with preference for the cluster of alpha1-2-mannose from the green alga Boodlea coacta is a potent entry inhibitor of HIV-1 and influenza viruses.Algal lectins as potential HIV microbicide candidates Inhibition of severe acute respiratory syndrome coronavirus replication in a lethal SARS-CoV BALB/c mouse model by stinging nettle lectin, Urtica dioica agglutinin.Griffithsin has antiviral activity against hepatitis C virus Griffithsin tandemers: flexible and potent lectin inhibitors of the human immunodeficiency virus Improving the large scale purification of the HIV microbicide, griffithsin.Occluding the mannose moieties on human immunodeficiency virus type 1 gp120 with griffithsin improves the antibody responses to both proteins in mice.Ready, set, fuse! The coronavirus spike protein and acquisition of fusion competence Griffithsin and Carrageenan Combination To Target Herpes Simplex Virus 2 and Human Papillomavirus.The role of individual carbohydrate-binding sites in the function of the potent anti-HIV lectin griffithsin.Hepatitis C Virus Resistance to Carbohydrate-Binding Agents Development of novel entry inhibitors targeting emerging viruses.Griffithsin protects mice from genital herpes by preventing cell-to-cell spread Rice endosperm is cost-effective for the production of recombinant griffithsin with potent activity against HIV.The griffithsin dimer is required for high-potency inhibition of HIV-1: evidence for manipulation of the structure of gp120 as part of the griffithsin dimer mechanism.Non-Antiretroviral Microbicides for HIV Prevention.Griffithsin-Modified Electrospun Fibers as a Delivery Scaffold To Prevent HIV Infection.Studies in a Murine Model Confirm the Safety of Griffithsin and Advocate Its Further Development as a Microbicide Targeting HIV-1 and Other Enveloped Viruses.Viral membranes: an emerging antiviral target for enveloped viruses?Advances in Developing Therapies to Combat Zika Virus: Current Knowledge and Future Perspectives Antiviral drug discovery: broad-spectrum drugs from nature.High-Mannose Specific Lectin and Its Recombinants from a Carrageenophyta Kappaphycus alvarezii Represent a Potent Anti-HIV Activity Through High-Affinity Binding to the Viral Envelope Glycoprotein gp120.Human lectins and their roles in viral infections.Marine lectins and their medicinal applications.Antiviral lectins: Selective inhibitors of viral entry.Griffithsin inhibits Japanese encephalitis virus infection in vitro and in vivo.Recent developments in anti-severe acute respiratory syndrome coronavirus chemotherapy High-Mannose Specific Lectin and Its Recombinants from a Carrageenophyta Kappaphycus alvarezii Represent a Potent Anti-HIV Activity Through High-Affinity Binding to the Viral Envelope Glycoprotein gp120.Fabrication and Characterization of Griffithsin-modified Fiber Scaffolds for Prevention of Sexually Transmitted Infections.

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Broad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family Coronaviridae

http://www.wikidata.org/entity/Q24648487

description

2010 nî lūn-bûn

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2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Broad-spectrum in vitro activi ...... es of the family Coronaviridae

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Broad-spectrum in vitro activi ...... es of the family Coronaviridae

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Journal of Virology

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P2093

Barbara Giomarelli

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Barry R O'Keefe

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Brian W Barnett

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Christine L Wohlford-Lenane

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Dale L Barnard

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James B McMahon

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Paul K S Chan

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Shilpa R Shenoy

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P2860

ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia.

Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia

Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component

Functional genomics highlights differential induction of antiviral pathways in the lungs of SARS-CoV-infected macaques

Crystallographic, thermodynamic, and molecular modeling studies of the mode of binding of oligosaccharides to the potent antiviral protein griffithsin

Coronavirus as a possible cause of severe acute respiratory syndrome

Isolation and characterization of griffithsin, a novel HIV-inactivating protein, from the red alga Griffithsia sp

Identification of a new human coronavirus

Identification of a novel coronavirus in patients with severe acute respiratory syndrome

A novel coronavirus associated with severe acute respiratory syndrome

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2511-21

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scholarly article

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2829157

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10.1128/JVI.02322-09

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P433

5

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84

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David Meyerholz

Kenneth E. Palmer

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2010-03-01T00:00:00Z

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20032190

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2820936

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