SPLUNC1 regulates airway surface liquid volume by protecting ENaC from proteolytic cleavage
about
Dual acute proinflammatory and antifibrotic pulmonary effects of short palate, lung, and nasal epithelium clone-1 after exposure to carbon nanotubesHuman parotid secretory protein is a lipopolysaccharide-binding protein: identification of an anti-inflammatory peptide domainSPLUNC1/BPIFA1 contributes to pulmonary host defense against Klebsiella pneumoniae respiratory infectionIdentification of the SPLUNC1 ENaC-inhibitory domain yields novel strategies to treat sodium hyperabsorption in cystic fibrosis airway epithelial culturesAirway surface liquid volume regulation determines different airway phenotypes in liddle compared with betaENaC-overexpressing miceEpithelial Anion Transport as Modulator of Chemokine SignalingMolecular basis for pH-dependent mucosal dehydration in cystic fibrosis airwaysAirway hydration and COPDIncreased susceptibility to pulmonary Pseudomonas infection in Splunc1 knockout miceBactericidal/Permeability-increasing protein fold-containing family member A1 in airway host protection and respiratory diseaseActivation of the epithelial sodium channel (ENaC) by the alkaline protease from Pseudomonas aeruginosaInnate immunity proteins and a new truncated form of SPLUNC1 in nasopharyngeal aspirates from infants with respiratory syncytial virus infection.The Concise Guide to PHARMACOLOGY 2013/14: ion channelsMarked increases in mucociliary clearance produced by synergistic secretory agonists or inhibition of the epithelial sodium channel.PLUNC is a novel airway surfactant protein with anti-biofilm activity.Little Cigars are More Toxic than Cigarettes and Uniquely Change the Airway Gene and Protein Expression.Investigation of anti-infection mechanism of lactoferricin and splunc-1.The multifunctional host defense peptide SPLUNC1 is critical for homeostasis of the mammalian upper airwayThe cystic fibrosis transmembrane conductance regulator impedes proteolytic stimulation of the epithelial Na+ channel.BPIFB1 (LPLUNC1) is upregulated in cystic fibrosis lung diseaseSPLUNC1 expression reduces surface levels of the epithelial sodium channel (ENaC) in Xenopus laevis oocytes.SPLUNC1 regulation in airway epithelial cells: role of Toll-like receptor 2 signalingAnalysis of the proteome of human airway epithelial secretionsSPLUNC1 regulates cell progression and apoptosis through the miR-141-PTEN/p27 pathway, but is hindered by LMP1.SPLUNC1 promotes lung innate defense against Mycoplasma pneumoniae infection in miceAntimicrobial activity of PLUNC protects against Pseudomonas aeruginosa infection.Proteomic analysis of pure human airway gland mucus reveals a large component of protective proteins.Automated acquisition and analysis of airway surface liquid height by confocal microscopyGammaherpesvirus infection modulates the temporal and spatial expression of SCGB1A1 (CCSP) and BPIFA1 (SPLUNC1) in the respiratory tract.SPLUNC1 Is a Significant Marker in Pleural Effusion from Lung Cancer Compared to Tuberculosis.Interleukin-13 Inhibits Lipopolysaccharide-Induced BPIFA1 Expression in Nasal Epithelial Cells.Reduced expression of antimicrobial PLUNC proteins in nasal polyp tissues of patients with chronic rhinosinusitis.Protein networks in induced sputum from smokers and COPD patients.Identification of SPLUNC1's ENaC-inhibitory domain yields novel strategies to treat sodium hyperabsorption in cystic fibrosis airways.Differential localisation of BPIFA1 (SPLUNC1) and BPIFB1 (LPLUNC1) in the nasal and oral cavities of mice.Multifunctional role of human SPLUNC1 in Pseudomonas aeruginosa infectionInhibition of airway surface fluid absorption by cholinergic stimulationA mechanochemical model for auto-regulation of lung airway surface layer volume.Reduced sodium transport with nasal administration of the prostasin inhibitor camostat in subjects with cystic fibrosis.Short palate, lung, and nasal epithelial clone-1 is a tightly regulated airway sensor in innate and adaptive immunity.
P2860
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P2860
SPLUNC1 regulates airway surface liquid volume by protecting ENaC from proteolytic cleavage
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
SPLUNC1 regulates airway surfa ...... ENaC from proteolytic cleavage
@ast
SPLUNC1 regulates airway surfa ...... ENaC from proteolytic cleavage
@en
SPLUNC1 regulates airway surfa ...... ENaC from proteolytic cleavage
@nl
type
label
SPLUNC1 regulates airway surfa ...... ENaC from proteolytic cleavage
@ast
SPLUNC1 regulates airway surfa ...... ENaC from proteolytic cleavage
@en
SPLUNC1 regulates airway surfa ...... ENaC from proteolytic cleavage
@nl
prefLabel
SPLUNC1 regulates airway surfa ...... ENaC from proteolytic cleavage
@ast
SPLUNC1 regulates airway surfa ...... ENaC from proteolytic cleavage
@en
SPLUNC1 regulates airway surfa ...... ENaC from proteolytic cleavage
@nl
P2093
P2860
P3181
P356
P1476
SPLUNC1 regulates airway surfa ...... ENaC from proteolytic cleavage
@en
P2093
Agustin Garcia-Caballero
Erol Gaillard
John C Olsen
Julia E Rasmussen
M Jackson Stutts
Michael J Watson
Robert Tarran
Scott H Donaldson
P2860
P304
P3181
P356
10.1073/PNAS.0903609106
P407
P577
2009-07-07T00:00:00Z