Diphthamide modification of eEF2 requires a J-domain protein and is essential for normal development
about
Identification and characterization of a novel evolutionarily conserved lysine-specific methyltransferase targeting eukaryotic translation elongation factor 2 (eEF2)Chemogenomic approach identified yeast YLR143W as diphthamide synthetaseStructure and mechanistic insights into novel iron-mediated moonlighting functions of human J-protein cochaperone, Dph4The diphthamide modification pathway from Saccharomyces cerevisiae--revisitedThe amidation step of diphthamide biosynthesis in yeast requires DPH6, a gene identified through mining the DPH1-DPH5 interaction networkLoss of diphthamide pre-activates NF-κB and death receptor pathways and renders MCF7 cells hypersensitive to tumor necrosis factorThe biosynthesis and biological function of diphthamideA dominant-negative approach that prevents diphthamide formation confers resistance to Pseudomonas exotoxin A and diphtheria toxinAnalysis of Pax6 contiguous gene deletions in the mouse, Mus musculus, identifies regions distinct from Pax6 responsible for extreme small-eye and belly-spotting phenotypesTowards a systems approach in the genetic analysis of archaea: Accelerating mutant construction and phenotypic analysis in Haloferax volcaniiEvolutionary Conservation and Emerging Functional Diversity of the Cytosolic Hsp70:J Protein Chaperone Network of Arabidopsis thalianaSilencing of diphthamide synthesis 3 (Dph3) reduces metastasis of murine melanoma.A guide to taming a toxin--recombinant immunotoxins constructed from Pseudomonas exotoxin A for the treatment of cancer.Antibody fusion proteins: anti-CD22 recombinant immunotoxin moxetumomab pasudotoxImmunotoxin resistance via reversible methylation of the DPH4 promoter is a unique survival strategy.The elongation, termination, and recycling phases of translation in eukaryotes.Diphthamide modification on eukaryotic elongation factor 2 is needed to assure fidelity of mRNA translation and mouse developmentImmunoconjugates in the management of hairy cell leukemia.Comparative genomic analysis of the DUF71/COG2102 family predicts roles in diphthamide biosynthesis and B12 salvage.Proteomics analysis of in vitro protein methylation during Src-induced transformation.Elp3 and Dph3 of Schizosaccharomyces pombe mediate cellular stress responses through tRNALysUUU modifications.Synthetic lethal interactions in yeast reveal functional roles of J protein co-chaperonesInfluence of DPH1 and DPH5 Protein Variants on the Synthesis of Diphthamide, the Target of ADPRibosylating Toxins.A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.Role of OVCA1/DPH1 in craniofacial abnormalities of Miller-Dieker syndrome.Diphthamide affects selenoprotein expression: Diphthamide deficiency reduces selenocysteine incorporation, decreases selenite sensitivity and pre-disposes to oxidative stressComplex Evolutionary History of Translation Elongation Factor 2 and Diphthamide Biosynthesis in Archaea and ParabasalidsImportance of diphthamide modified EF2 for translational accuracy and competitive cell growth in yeast
P2860
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P2860
Diphthamide modification of eEF2 requires a J-domain protein and is essential for normal development
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Diphthamide modification of eE ...... sential for normal development
@ast
Diphthamide modification of eE ...... sential for normal development
@en
Diphthamide modification of eE ...... sential for normal development
@nl
type
label
Diphthamide modification of eE ...... sential for normal development
@ast
Diphthamide modification of eE ...... sential for normal development
@en
Diphthamide modification of eE ...... sential for normal development
@nl
prefLabel
Diphthamide modification of eE ...... sential for normal development
@ast
Diphthamide modification of eE ...... sential for normal development
@en
Diphthamide modification of eE ...... sential for normal development
@nl
P2093
P2860
P356
P1476
Diphthamide modification of eE ...... sential for normal development
@en
P2093
Jackie Harrison
Lisa McKie
Lucie Vizor
Ruth Edgar
Sally H Cross
Tom R Webb
P2860
P304
P356
10.1242/JCS.035550
P407
P50
P577
2008-10-01T00:00:00Z