Next-generation SELEX identifies sequence and structural determinants of splicing factor binding in human pre-mRNA sequence
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Using positional distribution to identify splicing elements and predict pre-mRNA processing defects in human genesPtbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brainChallenges and opportunities for small molecule aptamer developmentAssociation between regulator of G protein signaling 9-2 and body weightA deep learning framework for modeling structural features of RNA-binding protein targets.De novo prediction of PTBP1 binding and splicing targets reveals unexpected features of its RNA recognition and function.Lineage-specific splicing of a brain-enriched alternative exon promotes glioblastoma progression.High expression of PTBP1 promote invasion of colorectal cancer by alternative splicing of cortactin.New Technologies Provide Quantum Changes in the Scale, Speed, and Success of SELEX Methods and Aptamer Characterization.A biophysical model for identifying splicing regulatory elements and their interactions.Combinatorial binding of transcription factors in the pluripotency control regions of the genome.Modular protein-RNA interactions regulating mRNA metabolism: a role for NMR.Recognizing RNA structural motifs in HT-SELEX data for ribosomal protein S15.RNA aptamer evolution: two decades of SELEction.New insights into functional roles of the polypyrimidine tract-binding protein.Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB.High-Throughput Assays to Assess the Functional Impact of Genetic Variants: A Road Towards Genomic-Driven Medicine.Frequent gain and loss of intronic splicing regulatory elements during the evolution of vertebrates.PTBP1-dependent regulation of USP5 alternative RNA splicing plays a role in glioblastoma tumorigenesis.Polypyrimidine tract-binding protein binds to the 5' untranslated region of the mouse mammary tumor virus mRNA and stimulates cap-independent translation initiation.Quantitative evaluation of all hexamers as exonic splicing elementsWidespread intra-dependencies in the removal of introns from human transcripts.PASSPORT-seq: A Novel High-Throughput Bioassay to Functionally Test Polymorphisms in Micro-RNA Target Sites.
P2860
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P2860
Next-generation SELEX identifies sequence and structural determinants of splicing factor binding in human pre-mRNA sequence
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Next-generation SELEX identifi ...... ing in human pre-mRNA sequence
@ast
Next-generation SELEX identifi ...... ing in human pre-mRNA sequence
@en
Next-generation SELEX identifi ...... ing in human pre-mRNA sequence
@nl
type
label
Next-generation SELEX identifi ...... ing in human pre-mRNA sequence
@ast
Next-generation SELEX identifi ...... ing in human pre-mRNA sequence
@en
Next-generation SELEX identifi ...... ing in human pre-mRNA sequence
@nl
prefLabel
Next-generation SELEX identifi ...... ing in human pre-mRNA sequence
@ast
Next-generation SELEX identifi ...... ing in human pre-mRNA sequence
@en
Next-generation SELEX identifi ...... ing in human pre-mRNA sequence
@nl
P2093
P2860
P356
P1433
P1476
Next-generation SELEX identifi ...... ing in human pre-mRNA sequence
@en
P2093
Brian L Chang
Daniel C Reid
Lauren Alpert
Samuel I Gunderson
William A Thompson
P2860
P304
P356
10.1261/RNA.1821809
P407
P577
2009-12-01T00:00:00Z