Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A) - Test2 - elhamkhani - TriplyDB

Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A)

Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A)

http://www.wikidata.org/entity/Q24655420

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SV2 mediates entry of tetanus neurotoxin into central neurons The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam Brivaracetam: a rational drug discovery success story Review of levetiracetam, with a focus on the extended release formulation, as adjuvant therapy in controlling partial-onset seizures New molecular targets for antiepileptic drugs: alpha(2)delta, SV2A, and K(v)7/KCNQ/M potassium channels Molecular targets for antiepileptic drug development SV2 renders primed synaptic vesicles competent for Ca2+ -induced exocytosis The iTRAPs: Guardians of Synaptic Vesicle Cargo Retrieval During Endocytosis Molecular mechanisms driving homeostatic plasticity of neurotransmitter release Opioid receptors: toward separation of analgesic from undesirable effects A systems level, functional genomics analysis of chronic epilepsy Synaptic Vesicle Glycoprotein 2A Ligands in the Treatment of Epilepsy and Beyond Brivaracetam (UCB 34714)Epilepsy caused by an abnormal alternative splicing with dosage effect of the SV2A gene in a chicken model Levetiracetam reverses synaptic deficits produced by overexpression of SV2A Exploring the interaction of SV2A with racetams using homology modelling, molecular dynamics and site-directed mutagenesis Development and Validation of a New Mouse Model to Investigate the Role of SV2A in Epilepsy SV2B regulates synaptotagmin 1 by direct interaction Prediction of gene-phenotype associations in humans, mice, and plants using phenologs Synaptic vesicle glycoprotein 2A (SV2A) regulates kindling epileptogenesis via GABAergic neurotransmission Modulation of the conformational state of the SV2A protein by an allosteric mechanism as evidenced by ligand binding assays.Early development of the gonadotropin-releasing hormone neuronal network in transgenic zebrafish Levetiracetam: the profile of a novel anticonvulsant drug-part I: preclinical data.The mammalian central nervous synaptic cleft contains a high density of periodically organized complexes Gene expression profiling of two distinct neuronal populations in the rodent spinal cord.Loss of the Synaptic Vesicle Protein SV2B results in reduced neurotransmission and altered synaptic vesicle protein expression in the retina.SVOP is a nucleotide binding protein.Levetiracetam attenuates hippocampal expression of synaptic plasticity-related immediate early and late response genes in amygdala-kindled rats Intravenous levetiracetam in the rat pilocarpine-induced status epilepticus model: behavioral, physiological and histological studies.Puzzling Out Synaptic Vesicle 2 Family Members Functions.Levetiracetam inhibits both ryanodine and IP3 receptor activated calcium induced calcium release in hippocampal neurons in culture.Cotrafficking of SV2 and synaptotagmin at the synapse.Levetiracetam as an alternative therapy for Tourette syndrome.Kisspeptins modulate the biology of multiple populations of gonadotropin-releasing hormone neurons during embryogenesis and adulthood in zebrafish (Danio rerio).SV2 acts via presynaptic calcium to regulate neurotransmitter release.Expression of synaptic vesicle protein 2A in epilepsy-associated brain tumors and in the peritumoral cortex.Molecular mechanisms of neurotransmitter release.SV2 regulates neurotransmitter release via multiple mechanisms.Nonsense-mediated mRNA decay and loss-of-function of the protein underlie the X-linked epilepsy associated with the W356× mutation in synapsin I.Loss of the SV2-like protein SVOP produces no apparent deficits in laboratory mice.

P2860

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P2860

Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A)

http://www.wikidata.org/entity/Q24655420

description

1999 nî lūn-bûn

@nan

1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

1999年の論文

@ja

1999年論文

@yue

1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

@wuu

name

Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A)

@ast

Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A)

@en

Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A)

@nl

type

label

Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A)

@ast

Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A)

@en

Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A)

@nl

prefLabel

Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A)

@ast

Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A)

@en

Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A)

@nl

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P356

PNAS.96.26.15268

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A)

@en

P2093

B D Hale

http://www.w3.org/2001/XMLSchema#string

C Chavkin

http://www.w3.org/2001/XMLSchema#string

H Z Zhang

http://www.w3.org/2001/XMLSchema#string

J M Gunther

http://www.w3.org/2001/XMLSchema#string

K M Crowder

http://www.w3.org/2001/XMLSchema#string

M R Peterson

http://www.w3.org/2001/XMLSchema#string

R H Scheller

http://www.w3.org/2001/XMLSchema#string

S M Bajjalieh

http://www.w3.org/2001/XMLSchema#string

T A Jones

http://www.w3.org/2001/XMLSchema#string

P2860

Brain contains two forms of synaptic vesicle protein 2

SNAP receptors implicated in vesicle targeting and fusion

Syntaxin: a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones

GABAergic cells are the major postsynaptic targets of mossy fibers in the rat hippocampus

The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation

SV2, a brain synaptic vesicle protein homologous to bacterial transporters

SVOP, an evolutionarily conserved synaptic vesicle protein, suggests novel transport functions of synaptic vesicles

Isoform-specific, calcium-regulated interaction of the synaptic vesicle proteins SV2 and synaptotagmin

Essential functions of synapsins I and II in synaptic vesicle regulation

Synaptotagmin I: a major Ca2+ sensor for transmitter release at a central synapse

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15268-73

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scholarly article

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1008071

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P356

10.1073/PNAS.96.26.15268

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P433

26

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P478

96

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1999-12-21T00:00:00Z

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51357266

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10611374

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P932

24809

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