Protective effects of NSAIDs on the development of Alzheimer disease - Test2 - elhamkhani - TriplyDB

Protective effects of NSAIDs on the development of Alzheimer disease

Protective effects of NSAIDs on the development of Alzheimer disease

http://www.wikidata.org/entity/Q24656148

about

Shared molecular and functional frameworks among five complex human disorders: a comparative study on interactomes linked to susceptibility genes Aspirin, steroidal and non-steroidal anti-inflammatory drugs for the treatment of Alzheimer's disease Use of ibuprofen and risk of Parkinson disease Microglial Priming and Alzheimer's Disease: A Possible Role for (Early) Immune Challenges and Epigenetics?Targeting innate immunity for neurodegenerative disorders of the central nervous system Genetic and Transcriptomic Profiles of Inflammation in Neurodegenerative Diseases: Alzheimer, Parkinson, Creutzfeldt-Jakob and Tauopathies Myeloid Dendritic Cells are Potential Players in Human Neurodegenerative Diseases Potential Therapeutical Contributions of the Endocannabinoid System towards Aging and Alzheimer's Disease Non-steroidal anti-inflammatory drugs and cognitive function: are prostaglandins at the heart of cognitive impairment in dementia and delirium?Diverse molecular targets for therapeutic strategies in Alzheimer's disease Antagonism of neuronal prostaglandin E(2) receptor subtype 1 mitigates amyloid β neurotoxicity in vitro The airbag problem-a potential culprit for bench-to-bedside translational efforts: relevance for Alzheimer's disease Viruses and neurodegeneration Neuroprotective and symptomatic effects of targeting group III mGlu receptors in neurodegenerative disease Enhanced longevity by ibuprofen, conserved in multiple species, occurs in yeast through inhibition of tryptophan import Stress Granules Modulate SYK to Cause Microglial Cell Dysfunction in Alzheimer's Disease.NO2 inhalation promotes Alzheimer's disease-like progression: cyclooxygenase-2-derived prostaglandin E2 modulation and monoacylglycerol lipase inhibition-targeted medication Does neuroinflammation fan the flame in neurodegenerative diseases?Ageing, neurodegeneration and brain rejuvenation Friend or foe: the dichotomous impact of T cells on neuro-de/re-generation during aging The Alzheimer pandemic: is paracetamol to blame?Short-term treatment with tolfenamic acid improves cognitive functions in Alzheimer's disease mice Prostaglandin signaling suppresses beneficial microglial function in Alzheimer's disease models.Human neural stem cells alleviate Alzheimer-like pathology in a mouse model.The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy.Dementia Prevention: optimizing the use of observational data for personal, clinical, and public health decision-making Modulation of microglial innate immunity in Alzheimer's disease by activation of peroxisome proliferator-activated receptor gamma.Cyclooxygenase-1 null mice show reduced neuroinflammation in response to beta-amyloid.Omega-3 fatty acids and dementia.Mitochondria-Derived Damage-Associated Molecular Patterns in Neurodegeneration.Molecular Targets for PET Imaging of Activated Microglia: The Current Situation and Future Expectations.Reduced cerebrospinal fluid concentration of interleukin-12/23 subunit p40 in patients with cognitive impairment.Intermittent fasting attenuates lipopolysaccharide-induced neuroinflammation and memory impairment.Voluntary Exercise Promotes Glymphatic Clearance of Amyloid Beta and Reduces the Activation of Astrocytes and Microglia in Aged Mice.In vivo evaluation of microglia activation by intracranial iron overload in central pain after spinal cord injury Why pleiotropic interventions are needed for Alzheimer's disease.Molecular dynamics simulations of anti-aggregation effect of ibuprofen.Presenilin/gamma-Secretase and Inflammation.Implications of gliotransmission for the pharmacotherapy of CNS disorders.CNS expression of anti-inflammatory cytokine interleukin-4 attenuates Alzheimer's disease-like pathogenesis in APP+PS1 bigenic mice

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P2860

Protective effects of NSAIDs on the development of Alzheimer disease

http://www.wikidata.org/entity/Q24656148

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2008 nî lūn-bûn

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2008 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2008 թվականի մայիսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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Protective effects of NSAIDs on the development of Alzheimer disease

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Protective effects of NSAIDs on the development of Alzheimer disease

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Protective effects of NSAIDs on the development of Alzheimer disease

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Steven C Vlad

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P2860

NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo

Who has diabetes? Best estimates of diabetes prevalence in the Department of Veterans Affairs based on computerized patient data.

Synthesis and biological activity of flurbiprofen analogues as selective inhibitors of beta-amyloid(1)(-)(42) secretion.

Alcohol and tobacco consumption as risk factors of dementia: a review of epidemiological studies.

The role of inflammation in Alzheimer's disease.

Non-steroidal anti-inflammatory drugs (NSAIDs) in Alzheimer's disease: old and new mechanisms of action.

Meta-analysis of nonsteroidal antiinflammatory drug use and risk of dementia.

Sodium salicylate inhibits prostaglandin formation without affecting the induction of cyclooxygenase-2 by bacterial lipopolysaccharide in vivo.

Randomized pilot study of nimesulide treatment in Alzheimer's disease.

Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial.

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Donald R Miller

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Alzheimer's disease

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