Isolation, synthesis, and antimicrobial activities of naturally occurring theta-defensin isoforms from baboon leukocytes
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Humanized theta-defensins (retrocyclins) enhance macrophage performance and protect mice from experimental anthrax infectionsThe Cyclic Cystine Ladder in -Defensins Is Important for Structure and Stability, but Not Antibacterial ActivityRTD-1mimic containing γPNA scaffold exhibits broad-spectrum antibacterial activitiesMolecular evolution of the primate α-/θ-defensin multigene family.Paneth cell α-defensins in enteric innate immunityRecombinant production of rhesus θ-defensin-1 (RTD-1) using a bacterial expression system.Efficient one-pot cyclization/folding of Rhesus θ-defensin-1 (RTD-1)Comparative genomics and evolution of the alpha-defensin multigene family in primatesEvolution of primate α and θ defensins revealed by analysis of genomes.The chemistry and biology of theta defensins.Rhesus macaque θ-defensin isoforms: expression, antimicrobial activities, and demonstration of a prominent role in neutrophil granule microbicidal activities.Rhesus macaque theta defensins suppress inflammatory cytokines and enhance survival in mouse models of bacteremic sepsis.Enteric alpha defensins in norm and pathology.High fidelity processing and activation of the human α-defensin HNP1 precursor by neutrophil elastase and proteinase 3Biological activities of natural and engineered cyclotides, a novel molecular scaffold for peptide-based therapeutics.Full Sequence Amino Acid Scanning of θ-Defensin RTD-1 Yields a Potent Anthrax Lethal Factor Protease Inhibitor.Rhesus macaque θ-defensin RTD-1 inhibits proinflammatory cytokine secretion and gene expression by inhibiting the activation of NF-κB and MAPK pathwaysAntimicrobial peptides: key components of the innate immune system.α-Defensins in human innate immunity.Structure and Biological Functions of β-Hairpin Antimicrobial Peptides.The Role of Defensins in HIV Pathogenesis.Simplified, serine-rich theta-defensin analogues as antitumour peptides.Efficacy of Rhesus Theta-Defensin-1 in Experimental Models of Pseudomonas aeruginosa Lung Infection and Inflammation.Convergent evolution of defensin sequence, structure and function.Killing of staphylococci by θ-defensins involves membrane impairment and activation of autolytic enzymesA hybrid cationic peptide composed of human β-defensin-1 and humanized θ-defensin sequences exhibits salt-resistant antimicrobial activity.Criterion for amino acid composition of defensins and antimicrobial peptides based on geometry of membrane destabilization.θ-Defensins: cyclic peptides with endless potential.Rhesus theta-defensin prevents death in a mouse model of severe acute respiratory syndrome coronavirus pulmonary disease.1-(2-aminophenyl)-1H-1,2,3-triazole-4-carboxylic acid: activity against Gram-positive and Gram-negative pathogens including Vibrio cholerae.A non-cyclic baboon θ-defensin derivative exhibiting antimicrobial activity against the phytopathogen Verticillium dahliae.Suppression and resolution of autoimmune arthritis by rhesus θ-defensin-1, an immunomodulatory macrocyclic peptide.In-cell production of a genetically-encoded library based on the θ-defensin RTD-1 using a bacterial expression system.Towards the Application of Human Defensins as Antivirals.Macrocyclic θ-defensins suppress tumor necrosis factor-α (TNF-α) shedding by inhibition of TNF-α converting enzyme.Fungicidal potency and mechanisms of θ-defensins against multi-drug resistant Candida species.
P2860
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P2860
Isolation, synthesis, and antimicrobial activities of naturally occurring theta-defensin isoforms from baboon leukocytes
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Isolation, synthesis, and anti ...... soforms from baboon leukocytes
@ast
Isolation, synthesis, and anti ...... soforms from baboon leukocytes
@en
Isolation, synthesis, and anti ...... soforms from baboon leukocytes
@nl
type
label
Isolation, synthesis, and anti ...... soforms from baboon leukocytes
@ast
Isolation, synthesis, and anti ...... soforms from baboon leukocytes
@en
Isolation, synthesis, and anti ...... soforms from baboon leukocytes
@nl
prefLabel
Isolation, synthesis, and anti ...... soforms from baboon leukocytes
@ast
Isolation, synthesis, and anti ...... soforms from baboon leukocytes
@en
Isolation, synthesis, and anti ...... soforms from baboon leukocytes
@nl
P2093
P2860
P356
P1476
Isolation, synthesis, and anti ...... soforms from baboon leukocytes
@en
P2093
Angie E Garcia
George Osapay
Michael E Selsted
Patti A Tran
P2860
P304
P356
10.1128/IAI.01100-08
P407
P577
2008-12-01T00:00:00Z