Revealing the architecture of gene regulation: the promise of eQTL studies - Test2 - elhamkhani - TriplyDB

Revealing the architecture of gene regulation: the promise of eQTL studies

Revealing the architecture of gene regulation: the promise of eQTL studies

http://www.wikidata.org/entity/Q24657564

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Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes Human genetics and genomics a decade after the release of the draft sequence of the human genome Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain Species-specific transcription in mice carrying human chromosome 21 Comparative studies of gene expression and the evolution of gene regulation Involvement of the atrial natriuretic peptide transcription factor GATA4 in alcohol dependence, relapse risk and treatment response to acamprosate RNA sequencing reveals the role of splicing polymorphisms in regulating human gene expression From Linkage Studies to Epigenetics: What We Know and What We Need to Know in the Neurobiology of Schizophrenia Next generation sequencing technology and genomewide data analysis: Perspectives for retinal research Candidate gene association studies: a comprehensive guide to useful in silico tools Annotating individual human genomes Towards the identification of the loci of adaptive evolution Genetic architecture of ethanol-responsive transcriptome variation in Saccharomyces cerevisiae strains.A survey of best practices for RNA-seq data analysis Erythro-megakaryocytic transcription factors associated with hereditary anemia Using gene-network landscape to dissect genotype effects of TCF7L2 genetic variant on diabetes and cardiovascular risk Characterizing the genetic basis of transcriptome diversity through RNA-sequencing of 922 individuals Genetic variants and risk of lung cancer in never smokers: a genome-wide association study Pleiotropy in complex traits: challenges and strategies A statistical framework for joint eQTL analysis in multiple tissues Public data and open source tools for multi-assay genomic investigation of disease A gene-based association method for mapping traits using reference transcriptome data The Genotype-Tissue Expression (GTEx) project Learning transcriptional regulatory relationships using sparse graphical models Exon-specific QTLs skew the inferred distribution of expression QTLs detected using gene expression array data Genetics and beyond--the transcriptome of human monocytes and disease susceptibility The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups Serious limitations of the QTL/microarray approach for QTL gene discovery.An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits.JOINT AND INDIVIDUAL VARIATION EXPLAINED (JIVE) FOR INTEGRATED ANALYSIS OF MULTIPLE DATA TYPES.iBMQ: a R/Bioconductor package for integrated Bayesian modeling of eQTL data.Publisher’s Note:Abstraction for data integration:Fusing mammalian molecular, cellular and phenotype big datasets for better knowledge extraction.Allelome.PRO, a pipeline to define allele-specific genomic features from high-throughput sequencing data.SPIRE, a modular pipeline for eQTL analysis of RNA-Seq data, reveals a regulatory hotspot controlling miRNA expression in C. elegans.High-resolution mapping of expression-QTLs yields insight into human gene regulation.Effects of cis and trans genetic ancestry on gene expression in African Americans.The value of animal models in predicting genetic susceptibility to complex diseases such as rheumatoid arthritis Construction of a high-resolution genetic linkage map and comparative genome analysis for the reef-building coral Acropora millepora.Modeling expression quantitative trait loci in data combining ethnic populations.Key considerations for measuring allelic expression on a genomic scale using high-throughput sequencing.

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Revealing the architecture of gene regulation: the promise of eQTL studies

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2008 nî lūn-bûn

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2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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Revealing the architecture of gene regulation: the promise of eQTL studies

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Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

Bmp4 and Morphological Variation of Beaks in Darwin's Finches

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

Variations in DNA elucidate molecular networks that cause disease

Genome-wide association study identifies novel breast cancer susceptibility loci

A second generation human haplotype map of over 3.1 million SNPs

A haplotype map of the human genome

Principal components analysis corrects for stratification in genome-wide association studies

The evolutionary significance of cis-regulatory mutations

Chance caught on the wing: cis-regulatory evolution and the origin of pigment patterns in Drosophila

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