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Dysfunctions of neuronal and glial intermediate filaments in disease

Dysfunctions of neuronal and glial intermediate filaments in disease

http://www.wikidata.org/entity/Q24657653

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Strategies for treatment in Alexander disease The involvement of microRNAs in neurodegenerative diseases Herpesviruses and intermediate filaments: close encounters with the third type Post-translational modifications of intermediate filament proteins: mechanisms and functions Epiplakin attenuates experimental mouse liver injury by chaperoning keratin reorganization Giant axonal neuropathy: An updated perspective on its pathology and pathogenesis.miRNA malfunction causes spinal motor neuron disease.Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in giant axonal neuropathy.White matter astrocytes in health and disease.Recommendations to enable drug development for inherited neuropathies: Charcot-Marie-Tooth and Giant Axonal Neuropathy.Intermediate filaments take the heat as stress proteins.Cellular levels of Grb2 and cytoskeleton stability are correlated in a neurodegenerative scenario.Gender dimorphic formation of mouse Mallory-Denk bodies and the role of xenobiotic metabolism and oxidative stress Rapid manifestation of reactive astrogliosis in acute hippocampal brain slices.mNos2 deletion and human NOS2 replacement in Alzheimer disease models In vivo evidence that TRAF4 is required for central nervous system myelin homeostasis Impact of vegf on astrocytes: analysis of gap junctional intercellular communication, proliferation, and motility.GFAP isoforms in adult mouse brain with a focus on neurogenic astrocytes and reactive astrogliosis in mouse models of Alzheimer disease.Suppression of extensive neurofilament phosphorylation rescues α-Internexin/peripherin-overexpressing PC12 cells from neuronal cell death.Astrocyte Dysfunction in Developmental Neurometabolic Diseases.Vimentin regulates activation of the NLRP3 inflammasome.Neurofilament light polypeptide gene N98S mutation in mice leads to neurofilament network abnormalities and a Charcot-Marie-Tooth Type 2E phenotype.Energy determinants GAPDH and NDPK act as genetic modifiers for hepatocyte inclusion formation.Intermediate filament protein accumulation in motor neurons derived from giant axonal neuropathy iPSCs rescued by restoration of gigaxonin A Stochastic Multiscale Model That Explains the Segregation of Axonal Microtubules and Neurofilaments in Neurological Diseases.A neuronal death model: overexpression of neuronal intermediate filament protein peripherin in PC12 cells Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy Keratin 8 phosphorylation regulates its transamidation and hepatocyte Mallory-Denk body formation.CSF and Blood Levels of GFAP in Alexander Disease GFAP expression as an indicator of disease severity in mouse models of Alexander disease.Alpha internexin expression related with molecular characteristics in adult glioblastoma and oligodendroglioma.Lamin aggregation is an early sensor of porphyria-induced liver injury "IF-pathies": a broad spectrum of intermediate filament-associated diseases.Adenosine A2A receptor deficiency alleviates blast-induced cognitive dysfunction.A conserved rod domain phosphotyrosine that is targeted by the phosphatase PTP1B promotes keratin 8 protein insolubility and filament organization Longitudinal study of differential protein expression in an Alzheimer's mouse model lacking inducible nitric oxide synthase.Intermediate filaments of the lung.Emerging role of autophagy in pediatric neurodegenerative and neurometabolic diseases.Lessons from Animal Models of Cytoplasmic Intermediate Filament Proteins.Intermediate Charcot-Marie-Tooth disease: an electrophysiological reappraisal and systematic review.

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Dysfunctions of neuronal and glial intermediate filaments in disease

http://www.wikidata.org/entity/Q24657653

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2009 nî lūn-bûn

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2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2009 թվականի հուլիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Dysfunctions of neuronal and glial intermediate filaments in disease

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Dysfunctions of neuronal and glial intermediate filaments in disease

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Dysfunctions of neuronal and glial intermediate filaments in disease

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Dysfunctions of neuronal and glial intermediate filaments in disease

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Dysfunctions of neuronal and glial intermediate filaments in disease

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Dysfunctions of neuronal and glial intermediate filaments in disease

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Dysfunctions of neuronal and glial intermediate filaments in disease

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Dysfunctions of neuronal and glial intermediate filaments in disease

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Journal of Clinical Investigation

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Dysfunctions of neuronal and glial intermediate filaments in disease

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Albee Messing

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Ronald K H Liem

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P2860

Mutations in the neurofilament light gene linked to Charcot-Marie-Tooth disease cause defects in transport

NF-M is an essential target for the myelin-directed "outside-in" signaling cascade that mediates radial axonal growth

Myotubularin-related 2 protein phosphatase and neurofilament light chain protein, both mutated in CMT neuropathies, interact in peripheral nerve

Charcot-Marie-Tooth disease type 2E, a disorder of the cytoskeleton

Effects of Charcot-Marie-Tooth-linked mutations of the neurofilament light subunit on intermediate filament formation

Gigaxonin-controlled degradation of MAP1B light chain is critical to neuronal survival

A new variant of Charcot-Marie-Tooth disease type 2 is probably the result of a mutation in the neurofilament-light gene.

Overexpression of the human NFM subunit in transgenic mice modifies the level of endogenous NFL and the phosphorylation state of NFH subunits

GFAP and its role in Alexander disease

The gene encoding gigaxonin, a new member of the cytoskeletal BTB/kelch repeat family, is mutated in giant axonal neuropathy

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10.1172/JCI38003

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