Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation
about
A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2PDendritic spines elongate after stimulation of group 1 metabotropic glutamate receptors in cultured hippocampal neurons.Fragile X syndrome: loss of local mRNA regulation alters synaptic development and functionGroup 1 mGluR-dependent synaptic long-term depression: mechanisms and implications for circuitry and diseaseA cellular mechanism for targeting newly synthesized mRNAs to synaptic sites on dendritesA direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome.Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficitsMolecular and cognitive predictors of the continuum of autistic behaviours in fragile XColocalization of integrin receptors and reelin in dendritic spine postsynaptic densities of adult nonhuman primate cortexInhibition of p21-activated kinase rescues symptoms of fragile X syndrome in mice.The gene encoding the fragile X RNA-binding protein is controlled by nuclear respiratory factor 2 and the CREB family of transcription factors.Dendritic mRNAs encode diversified functionalities in hippocampal pyramidal neuronsClinical and Neurobiological Relevance of Current Animal Models of Autism Spectrum Disorders.Single-Nucleotide Mutations in FMR1 Reveal Novel Functions and Regulatory Mechanisms of the Fragile X Syndrome Protein FMRPEmerging pharmacologic treatment options for fragile X syndromeFragile X syndrome and targeted treatment trials.Dendritic spine dysgenesis in autism related disordersUnstable mutations in the FMR1 gene and the phenotypesThe pathophysiology of fragile X (and what it teaches us about synapses)Channelopathies and dendritic dysfunction in fragile X syndrome.Regulatory BC1 RNA and the fragile X mental retardation protein: convergent functionality in brainReview of targeted treatments in fragile X syndromeG-quadruplexes: Emerging roles in neurodegenerative diseases and the non-coding transcriptomeFragile X mental retardation protein: A paradigm for translational control by RNA-binding proteinsA new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stabilityIn vitro and in cellulo evidences for association of the survival of motor neuron complex with the fragile X mental retardation proteinTranslational regulation of the human achaete-scute homologue-1 by fragile X mental retardation proteinThe fragile X gene and its functionIdentification of mRNA/protein (mRNP) complexes containing Puralpha, mStaufen, fragile X protein, and myosin Va and their association with rough endoplasmic reticulum equipped with a kinesin motorFrom mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndromeLocalization of FMRP-associated mRNA granules and requirement of microtubules for activity-dependent trafficking in hippocampal neuronsThe fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif.Roles of fragile X mental retardation protein in dopaminergic stimulation-induced synapse-associated protein synthesis and subsequent alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-4-propionate (AMPA) receptor internalizationClustered coding variants in the glutamate receptor complexes of individuals with schizophrenia and bipolar disorderPositive feedback regulation of Akt-FMRP pathway protects neurons from cell deathTransport of fragile X mental retardation protein via granules in neurites of PC12 cells.Exploring the zebra finch Taeniopygia guttata as a novel animal model for the speech-language deficit of fragile X syndromeExpression of fragile X mental retardation protein within the vocal control system of developing and adult male zebra finchesPremutation in the Fragile X Mental Retardation 1 (FMR1) Gene Affects Maternal Zn-milk and Perinatal Brain Bioenergetics and Scaffolding.Progress toward therapeutic potential for AFQ056 in Fragile X syndrome.
P2860
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P2860
Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation
description
1997 nî lūn-bûn
@nan
1997 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Fragile X mental retardation p ...... to neurotransmitter activation
@ast
Fragile X mental retardation p ...... to neurotransmitter activation
@en
Fragile X mental retardation p ...... to neurotransmitter activation
@nl
type
label
Fragile X mental retardation p ...... to neurotransmitter activation
@ast
Fragile X mental retardation p ...... to neurotransmitter activation
@en
Fragile X mental retardation p ...... to neurotransmitter activation
@nl
prefLabel
Fragile X mental retardation p ...... to neurotransmitter activation
@ast
Fragile X mental retardation p ...... to neurotransmitter activation
@en
Fragile X mental retardation p ...... to neurotransmitter activation
@nl
P2093
P2860
P3181
P356
P1476
Fragile X mental retardation p ...... to neurotransmitter activation
@en
P2093
A D Brazelton
C M Spencer
I J Weiler
J Eberwine
K Miyashiro
T A Comery
W T Greenough
P2860
P304
P3181
P356
10.1073/PNAS.94.10.5395
P407
P577
1997-05-01T00:00:00Z