Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding - Test2 - elhamkhani - TriplyDB

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

http://www.wikidata.org/entity/Q24657908

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ABC transporter functions as a pacemaker for sequestration of plant glucosides in leaf beetles Plant Lessons: Exploring ABCB Functionality Through Structural Modeling Mechanisms of CFTR Folding at the Endoplasmic Reticulum Clitocine reversal of P-glycoprotein associated multi-drug resistance through down-regulation of transcription factor NF-κB in R-HepG2 cell line Localization of putative binding sites for cyclic guanosine monophosphate and the anti-cancer drug 5-fluoro-2'-deoxyuridine-5'-monophosphate on ABCC11 in silico models Two ABCB4 point mutations of strategic NBD-motifs do not prevent protein targeting to the plasma membrane but promote MDR3 dysfunction 2-Aminothiazoles as therapeutic leads for prion diseases Structure of a cation-bound multidrug and toxic compound extrusion transporter Targeting Epithelial-Mesenchymal Transition (EMT) to Overcome Drug Resistance in Cancer Direct-Acting Oral Anticoagulants: Practical Considerations for Emergency Medicine Physicians The effect of ABCB1 polymorphisms on the outcome of breast cancer treatment Providing a molecular mechanism for P-glycoprotein; why would I bother?Bypassing P-Glycoprotein Drug Efflux Mechanisms: Possible Applications in Pharmacoresistant Schizophrenia Therapy Defining the blanks--pharmacochaperoning of SLC6 transporters and ABC transporters Exploiting nanotechnology to overcome tumor drug resistance: Challenges and opportunities Multifunctional nanoparticles for brain tumor imaging and therapy.Mammalian P4-ATPases and ABC transporters and their role in phospholipid transport Computational methods in drug discovery The role of transporters in toxicity and disease Polymer-drug conjugates: origins, progress to date and future directions Epothilones: From discovery to clinical trials Two ATPases Small and Innovative Molecules as New Strategy to Revert MDR Developmental and pathological angiogenesis in the central nervous system Strategies to potentiate antimicrobial photoinactivation by overcoming resistant phenotypes Multiple Drug Transport Pathways through Human P-Glycoprotein.Integrated analysis of residue coevolution and protein structure in ABC transporters Inter-domain communication mechanisms in an ABC importer: a molecular dynamics study of the MalFGK2E complex Cryo-EM Analysis of the Conformational Landscape of Human P-glycoprotein (ABCB1) During its Catalytic Cycle.Insights into How Nucleotide-Binding Domains Power ABC Transport Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant A Single Acidic Residue Can Guide Binding Site Selection but Does Not Govern QacR Cationic-Drug Affinity Crystal structure of the maltose transporter in a pretranslocation intermediate state Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR The structural basis of modularity in ECF-type ABC transporters Snapshots of the maltose transporter during ATP hydrolysis Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR): THREE-DIMENSIONAL STRUCTURE AND LOCALIZATION OF A CHANNEL GATE Structures of a Na+-coupled, substrate-bound MATE multidrug transporter Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation

P2860

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P2860

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

http://www.wikidata.org/entity/Q24657908

description

2009 nî lūn-bûn

@nan

2009 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի մարտին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

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Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

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Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

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type

label

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

@ast

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

@en

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

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altLabel

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

@en

prefLabel

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

@ast

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

@en

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

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SCIENCE.1168750

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Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

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Andrew Ward

http://www.w3.org/2001/XMLSchema#string

Geoffrey Chang

http://www.w3.org/2001/XMLSchema#string

Ina L Urbatsch

http://www.w3.org/2001/XMLSchema#string

Jodie Yu

http://www.w3.org/2001/XMLSchema#string

Patina M Harrell

http://www.w3.org/2001/XMLSchema#string

Qinghai Zhang

http://www.w3.org/2001/XMLSchema#string

Rupeng Zhuo

http://www.w3.org/2001/XMLSchema#string

Srinivas Chittaboina

http://www.w3.org/2001/XMLSchema#string

Stephen G Aller

http://www.w3.org/2001/XMLSchema#string

Yenphuong T Trinh

http://www.w3.org/2001/XMLSchema#string

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Flexibility in the ABC transporter MsbA: Alternating access with a twist.

The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity

The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism

Crystal structure of bacterial multidrug efflux transporter AcrB

Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter

An inward-facing conformation of a putative metal-chelate-type ABC transporter

Structure of an ABC transporter in complex with its binding protein

X-ray structure of EmrE supports dual topology model.

Crystal structure of a catalytic intermediate of the maltose transporter

Biochemistry of multidrug resistance mediated by the multidrug transporter

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1718-1722

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scholarly article

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1611098

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10.1126/SCIENCE.1168750

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323

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2009-03-01T00:00:00Z

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19325113

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2720052

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