Identification of carboxypeptidase N as an enzyme responsible for C-terminal cleavage of stromal cell-derived factor-1alpha in the circulation
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Regulation of Chemokine Activity - A Focus on the Role of Dipeptidyl Peptidase IV/CD26C-terminal clipping of chemokine CCL1/I-309 enhances CCR8-mediated intracellular calcium release and anti-apoptotic activityExome analysis reveals differentially mutated gene signatures of stage, grade and subtype in breast cancers.Computational protein design to reengineer stromal cell-derived factor-1α generates an effective and translatable angiogenic polypeptide analog.Low-dose bone morphogenetic protein-2/stromal cell-derived factor-1β cotherapy induces bone regeneration in critical-size rat calvarial defects.Fine-tune regulation of carboxypeptidase N1 controls vascular patterning during zebrafish development.Sustained release of engineered stromal cell-derived factor 1-α from injectable hydrogels effectively recruits endothelial progenitor cells and preserves ventricular function after myocardial infarction.Identification and characterization of circulating variants of CXCL12 from human plasma: effects on chemotaxis and mobilization of hematopoietic stem and progenitor cells.Inkjet-based biopatterning of SDF-1β augments BMP-2-induced repair of critical size calvarial bone defects in mice.Combined use of a solid-phase hexapeptide ligand library with liquid chromatography and two-dimensional difference gel electrophoresis for intact plasma proteomics.Stromal cell-derived factor-1β mediates cell survival through enhancing autophagy in bone marrow-derived mesenchymal stem cells.Total body irradiation is permissive for mesenchymal stem cell-mediated new bone formation following local transplantation.The ins and outs of hematopoietic stem cells: studies to improve transplantation outcomes.Proteolytic processing of SDF-1alpha reveals a change in receptor specificity mediating HIV-associated neurodegenerationParacrine SDF-1α signaling mediates the effects of PSCs on GEM chemoresistance through an IL-6 autocrine loop in pancreatic cancer cells.Carboxypeptidase Z (CPZ) links thyroid hormone and Wnt signaling pathways in growth plate chondrocytesG-CSF down-regulation of CXCR4 expression identified as a mechanism for mobilization of myeloid cells.Targeted disruption of the gene encoding the murine small subunit of carboxypeptidase N (CPN1) causes susceptibility to C5a anaphylatoxin-mediated shock.Intrafibrillar silicification of collagen scaffolds for sustained release of stem cell homing chemokine in hard tissue regeneration.A novel recombinant antibody specific to full-length stromal derived factor-1 for potential application in biomarker studies.A locked, dimeric CXCL12 variant effectively inhibits pulmonary metastasis of CXCR4-expressing melanoma cells due to enhanced serum stabilityMesenchymal stem cell expression of stromal cell-derived factor-1β augments bone formation in a model of local regenerative therapy.Stromal cell-derived factor-1β potentiates bone morphogenetic protein-2-stimulated osteoinduction of genetically engineered bone marrow-derived mesenchymal stem cells in vitro.Structural perspectives on antimicrobial chemokines.Structure and function of human plasma carboxypeptidase N, the anaphylatoxin inactivatorFunctional diversity of SDF-1 splicing variants.Natural nitration of CXCL12 reduces its signaling capacity and chemotactic activity in vitro and abrogates intra-articular lymphocyte recruitment in vivo.Proteolytic regulatory mechanism of chemerin bioactivity.Molecular mechanisms underlying adhesion and migration of hematopoietic stem cells.Re-engineered stromal cell-derived factor-1α and the future of translatable angiogenic polypeptide design.The potential of carboxypeptidase M as a therapeutic target in cancer.In vivo regulation of chemokine activity by post-translational modification.Effect of copper variation in yeast hydrolysate on C-terminal lysine levels of a monoclonal antibody.Expression of SDF-1 and CXCR4 transcript variants and CXCR7 in epithelial ovarian cancer.Extracellular molecules in hematopoietic stem cell mobilisation.Multi-omics Analysis of Serum Samples Demonstrates Reprogramming of Organ Functions Via Systemic Calcium Mobilization and Platelet Activation in Metastatic Melanoma.Mesenchymal stem cell expression of SDF-1β synergizes with BMP-2 to augment cell-mediated healing of critical-sized mouse calvarial defects.SDF-1α in glycan nanoparticles exhibits full activity and reduces pulmonary hypertension in rats.Ethanol dependence of alpha 1-antitrypsin C-terminal Lys truncation mediated by basic carboxypeptidases.CXCL12/CXCR4/CXCR7 Chemokine Axis in the Central Nervous System: Therapeutic Targets for Remyelination in Demyelinating Diseases.
P2860
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P2860
Identification of carboxypeptidase N as an enzyme responsible for C-terminal cleavage of stromal cell-derived factor-1alpha in the circulation
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Identification of carboxypepti ...... ctor-1alpha in the circulation
@ast
Identification of carboxypepti ...... ctor-1alpha in the circulation
@en
Identification of carboxypepti ...... ctor-1alpha in the circulation
@nl
type
label
Identification of carboxypepti ...... ctor-1alpha in the circulation
@ast
Identification of carboxypepti ...... ctor-1alpha in the circulation
@en
Identification of carboxypepti ...... ctor-1alpha in the circulation
@nl
prefLabel
Identification of carboxypepti ...... ctor-1alpha in the circulation
@ast
Identification of carboxypepti ...... ctor-1alpha in the circulation
@en
Identification of carboxypepti ...... ctor-1alpha in the circulation
@nl
P2093
P2860
P3181
P1433
P1476
Identification of carboxypepti ...... ctor-1alpha in the circulation
@en
P2093
David A Davis
Fuquan Yang
Giovanna Tosato
Henry M Fales
Kathleen E Singer
Maria De La Luz Sierra
Robert Yarchoan
P2860
P304
P3181
P356
10.1182/BLOOD-2004-12-4618
P407
P577
2005-02-17T00:00:00Z