Pixantrone can be activated by formaldehyde to generate a potent DNA adduct forming agent - Test2 - elhamkhani - TriplyDB

Pixantrone can be activated by formaldehyde to generate a potent DNA adduct forming agent

Pixantrone can be activated by formaldehyde to generate a potent DNA adduct forming agent

http://www.wikidata.org/entity/Q24671854

about

Asymmetric enzymatic glycosylation of mitoxantrone Monotherapy with pixantrone in histologically confirmed relapsed or refractory aggressive B-cell non-Hodgkin lymphoma: post-hoc analyses from a phase III trial.CpG methylation potentiates pixantrone and doxorubicin-induced DNA damage and is a marker of drug sensitivity.Initial testing (stage 1) of the topoisomerase II inhibitor pixantrone, by the pediatric preclinical testing program.Pixantrone for the treatment of aggressive non-Hodgkin lymphoma.Pharmacokinetic evaluation of pixantrone for the treatment of non-Hodgkin's lymphoma.Pixantrone: merging safety with efficacy.Binding of pixantrone to DNA at CpA dinucleotide sequences and bulge structures.The Servier oncology pipeline in 2017.Pixantrone induces cell death through mitotic perturbations and subsequent aberrant cell divisions.Pixantrone: A Review in Relapsed or Refractory Aggressive Non-Hodgkin's Lymphoma.Reversible and formaldehyde-mediated covalent binding of a bis-amino mitoxantrone analogue to DNA.

P2860

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P2860

Pixantrone can be activated by formaldehyde to generate a potent DNA adduct forming agent

http://www.wikidata.org/entity/Q24671854

description

2007 nî lūn-bûn

@nan

2007 թուականին հրատարակուած գիտական յօդուած

@hyw

2007 թվականին հրատարակված գիտական հոդված

@hy

2007年の論文

@ja

2007年学术文章

@wuu

2007年学术文章

@zh-cn

2007年学术文章

@zh-hans

2007年学术文章

@zh-my

2007年学术文章

@zh-sg

2007年學術文章

@yue

name

Pixantrone can be activated by formaldehyde to generate a potent DNA adduct forming agent

@ast

Pixantrone can be activated by formaldehyde to generate a potent DNA adduct forming agent

@en

Pixantrone can be activated by formaldehyde to generate a potent DNA adduct forming agent

@nl

type

label

Pixantrone can be activated by formaldehyde to generate a potent DNA adduct forming agent

@ast

Pixantrone can be activated by formaldehyde to generate a potent DNA adduct forming agent

@en

Pixantrone can be activated by formaldehyde to generate a potent DNA adduct forming agent

@nl

prefLabel

Pixantrone can be activated by formaldehyde to generate a potent DNA adduct forming agent

@ast

Pixantrone can be activated by formaldehyde to generate a potent DNA adduct forming agent

@en

Pixantrone can be activated by formaldehyde to generate a potent DNA adduct forming agent

@nl

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Nucleic Acids Research

P1476

Pixantrone can be activated by formaldehyde to generate a potent DNA adduct forming agent

@en

P2093

Ben J Evison

http://www.w3.org/2001/XMLSchema#string

Don R Phillips

http://www.w3.org/2001/XMLSchema#string

Ernesto Menta

http://www.w3.org/2001/XMLSchema#string

Oula C Mansour

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P2860

Immunocytochemical and biochemical demonstration of formaldhyde dehydrogenase (class III alcohol dehydrogenase) in the nucleus

Phase-II study of the new aza-anthracenedione, BBR 2778, in patients with relapsed aggressive non-Hodgkin's lymphomas.

Pixantrone (Novuspharma).

Topoisomerase II DNA cleavage stimulation, DNA binding activity, cytotoxicity, and physico-chemical properties of 2-aza- and 2-aza-oxide-anthracenedione derivatives.

6,9-Bis[(aminoalkyl)amino]benzo[g]isoquinoline-5,10-diones. A novel class of chromophore-modified antitumor anthracene-9,10-diones: synthesis and antitumor evaluations.

Activity of two novel anthracene-9,10-diones against human leukemia cells containing intercalator-sensitive or -resistant forms of topoisomerase II.

Antitumor agents. 1. 1,4-Bis[(aminoalkyl)amino]-9,10-anthracenediones.

Mitoxantrone. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in the chemotherapy of cancer.

Cytosine methylation enhances mitoxantrone-DNA adduct formation at CpG dinucleotides.

Production of formaldehyde from N5-methyltetrahydrofolate by normal and leukemic leukocytes.

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3581-9

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scholarly article

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4880279

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10.1093/NAR/GKM285

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11

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35

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Suzanne M Cutts

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2007-01-01T00:00:00Z

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6346927

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17483512

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1920253

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