Transmission of cell stress from endoplasmic reticulum to mitochondria: enhanced expression of Lon protease
about
Two proteases, trypsin domain-containing 1 (Tysnd1) and peroxisomal lon protease (PsLon), cooperatively regulate fatty acid β-oxidation in peroxisomal matrixThermodynamic characterization of specific interactions between the human Lon protease and G-quartet DNAIslet amyloid in type 2 diabetes, and the toxic oligomer hypothesisCell death and survival through the endoplasmic reticulum-mitochondrial axisMultitasking in the mitochondrion by the ATP-dependent Lon proteaseEvolution and significance of the Lon gene family in Arabidopsis organelle biogenesis and energy metabolismStructural properties of substrate proteins determine their proteolysis by the mitochondrial AAA+ protease Pim1.Mitochondrial Lon protease in human disease and aging: Including an etiologic classification of Lon-related diseases and disordersInflammation and cellular stress: a mechanistic link between immune-mediated and metabolically driven pathologiesOxygen consumption and usage during physical exercise: the balance between oxidative stress and ROS-dependent adaptive signalingEvidence that two ATP-dependent (Lon) proteases in Borrelia burgdorferi serve different functionsKeap1-Independent Regulation of Nrf2 Activity by Protein Acetylation and a BET Bromodomain ProteinRole of Herp in the endoplasmic reticulum stress responseTetramethylpyrazine blocks TFAM degradation and up-regulates mitochondrial DNA copy number by interacting with TFAM.TRPC1 inhibits apoptotic cell degeneration induced by dopaminergic neurotoxin MPTP/MPP(+).Protein modulation in mouse heart under acute and chronic hypoxia.4-O-carboxymethyl ascochlorin causes ER stress and induced autophagy in human hepatocellular carcinoma cells.Mitochondrial Lon protease regulates mitochondrial DNA copy number and transcription by selective degradation of mitochondrial transcription factor A (TFAM)Biological roles of the Podospora anserina mitochondrial Lon protease and the importance of its N-domain.Phosphorylation of human TFAM in mitochondria impairs DNA binding and promotes degradation by the AAA+ Lon protease.Upregulation of the mitochondrial Lon Protease allows adaptation to acute oxidative stress but dysregulation is associated with chronic stress, disease, and aging.Mitochondrial Lon protease at the crossroads of oxidative stress, ageing and cancer.CODAS syndrome is associated with mutations of LONP1, encoding mitochondrial AAA+ Lon protease.Inhibition of Lon blocks cell proliferation, enhances chemosensitivity by promoting apoptosis and decreases cellular bioenergetics of bladder cancer: potential roles of Lon as a prognostic marker and therapeutic target in baldder cancer.Down-regulating overexpressed human Lon in cervical cancer suppresses cell proliferation and bioenergetics.Active-site-directed chemical tools for profiling mitochondrial Lon protease.Mitochondrial (dys)function - a factor underlying the variability of efavirenz-induced hepatotoxicity?The mitochondrial ATP-dependent Lon protease: a novel target in lymphoma death mediated by the synthetic triterpenoid CDDO and its derivatives.Induction of dsRNA-activated protein kinase links mitochondrial unfolded protein response to the pathogenesis of intestinal inflammation.Matrix proteases in mitochondrial DNA function.Mitochondrial Lon regulates apoptosis through the association with Hsp60-mtHsp70 complex.Integration of cellular bioenergetics with mitochondrial quality control and autophagy.Functional mechanics of the ATP-dependent Lon protease- lessons from endogenous protein and synthetic peptide substrates.Overexpression of Lon contributes to survival and aggressive phenotype of cancer cells through mitochondrial complex I-mediated generation of reactive oxygen species.ATP-dependent proteases differ substantially in their ability to unfold globular proteinsThe mechanisms of brain ischemic insult and potential protective interventions.The peroxisomal Lon protease LonP2 in aging and disease: functions and comparisons with mitochondrial Lon protease LonP1Mitochondrial Lon is over-expressed in high-grade gliomas, and mediates hypoxic adaptation: potential role of Lon as a therapeutic target in glioma.Mitochondrial stress: a bridge between mitochondrial dysfunction and metabolic diseases?The multifaceted role of Lon proteolysis in seedling establishment and maintenance of plant organelle function: living from protein destruction.
P2860
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P2860
Transmission of cell stress from endoplasmic reticulum to mitochondria: enhanced expression of Lon protease
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Transmission of cell stress fr ...... ced expression of Lon protease
@ast
Transmission of cell stress fr ...... ced expression of Lon protease
@en
Transmission of cell stress fr ...... ced expression of Lon protease
@nl
type
label
Transmission of cell stress fr ...... ced expression of Lon protease
@ast
Transmission of cell stress fr ...... ced expression of Lon protease
@en
Transmission of cell stress fr ...... ced expression of Lon protease
@nl
prefLabel
Transmission of cell stress fr ...... ced expression of Lon protease
@ast
Transmission of cell stress fr ...... ced expression of Lon protease
@en
Transmission of cell stress fr ...... ced expression of Lon protease
@nl
P2093
P2860
P921
P3181
P356
P1476
Transmission of cell stress fr ...... ced expression of Lon protease
@en
P2093
Atsushi Yamaguchi
David M Stern
Fusae Ichinoda
Kentaro Ozawa
Masaya Tohyama
Mayuki Miyazaki
Naoya Sato
Osamu Hori
Satoshi Ogawa
Takashi Tamatani
P2860
P304
P3181
P356
10.1083/JCB.200108103
P407
P577
2002-06-24T00:00:00Z