A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles
about
Characterization of CYP2A13*2, a variant cytochrome P450 allele previously found to be associated with decreased incidences of lung adenocarcinoma in smokersOrganization and evolution of the Cyp2 gene cluster on mouse chromosome 7, and comparison with the syntenic human clusterStructural insight into the altered substrate specificity of human cytochrome P450 2A6 mutantsPolymorphisms of CYP2A6 and its practical consequencesGenomic Landscape of Experimental Bladder Cancer in Rodents and Its Application to Human Bladder Cancer: Gene Amplification and Potential Overexpression of Cyp2a5/CYP2A6 Are Associated with the Invasive PhenotypePolymorphisms of xenobiotic-metabolizing enzymes and susceptibility to cancerIdentification of novel CYP2A6*1B variants: the CYP2A6*1B allele is associated with faster in vivo nicotine metabolism.Nicotine dependenceMetabolic activation of toxins: tissue-specific expression and metabolism in target organs.Genetic influences on smoking: candidate genes.Is the hair nicotine level a more accurate biomarker of environmental tobacco smoke exposure than urine cotinine?Association of CYP2A6 deletion polymorphism with smoking habit and development of pulmonary emphysema.Inhibition and inactivation of cytochrome P450 2A6 and cytochrome P450 2A13 by menthofuran, β-nicotyrine and mentholSelective expression of CYP2A13 in human pancreatic α-islet cells.Genetic Determinants of 1,3-Butadiene Metabolism and Detoxification in Three Populations of Smokers with Different Risks of Lung Cancer.N-7-Alkyl-2'-Deoxyguanosine as surrogate biomarkers for N-nitrosamine exposure in human lung.Nicotine dependence pharmacogenetics: role of genetic variation in nicotine-metabolizing enzymesExpression of CYP2A6, CYP2D6 and CYP4A11 Polymorphisms in COS7 Mammalian Cell Line.Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity.Pharmacokinetic and pharmacodynamics studies of nicotine after oral administration in mice: effects of methoxsalen, a CYP2A5/6 inhibitor.Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes.Distribution of polymorphic variants of CYP2A6 and their involvement in nicotine addiction.Key residues controlling binding of diverse ligands to human cytochrome P450 2A enzymes.Genetic polymorphisms in human CYP2A6 gene causing impaired nicotine metabolismPhotoaffinity labeling probe for the substrate binding site of human phenol sulfotransferase (SULT1A1): 7-azido-4-methylcoumarin.Novel CYP2A6 diplotypes identified through next-generation sequencing are associated with in-vitro and in-vivo nicotine metabolism.
P2860
Q24648582-D2852341-2B2B-4CAB-8E44-A27CBDED8BD3Q24816889-9C1D88F7-FABF-442D-A226-A50761595F69Q27645089-5A4C43F8-28CD-4B29-9764-322B57EEE4E8Q28362536-10DE2866-0A8F-469B-9025-383B0EBD6000Q28395447-D9107A2A-56B8-44F3-93C9-F05D744F4AE5Q33608783-75227544-461C-4662-95B3-70738C9EA180Q34067100-0D556E7F-285A-480A-A7F9-1373FF7A367DQ34450836-95F745AB-42CB-4036-B6F7-D92E007426D7Q34638922-DEF28E83-0A50-4E12-BA9E-D2DF35B05971Q34938233-D153DAC3-A58D-4764-903F-4B7C4751030BQ35406444-607E3E91-4BAF-4ED3-A513-E74DDF5A6C2AQ35536013-FECAAE3E-7DBE-4C26-8486-F1FD7ACC54A3Q35995622-8F1BB9F7-9153-4900-AE5C-77AABEE90D47Q36296210-99ABE1CC-E31D-4591-9EE8-8A17819087DBQ36307933-027255D5-1D95-4399-BD5B-BB3FD9ECDE49Q36996089-B3A893E8-1C1A-4DEC-B0C6-DF983BEDC30AQ37169244-B584B1DE-A61B-42A8-954F-62EE3FAFD0CFQ37326678-412998A2-A1FF-4C6D-B25D-70489B8AD996Q37358027-1A484DFF-201C-4FCD-B95B-AEB861FE5C63Q37395538-465F9A28-7821-4191-BF48-5B9A0397D4F4Q37395740-831D555E-CDEB-4AEF-B404-3682286A4195Q38683483-ACF67F64-ED74-43E8-B8BA-2D6169F265FAQ42132207-3CC3DCA8-2F30-4931-BA6F-A4EF2085A6DAQ42284318-424C5D37-BE89-4500-8D65-E33AC7557BC1Q42846738-996FEA08-4344-4B47-9374-A524F0A9FF6FQ47565250-8A666322-769D-470C-964A-C1A05DEFDD20
P2860
A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles
description
1995 nî lūn-bûn
@nan
1995 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
A genetic polymorphism in coum ...... tion of variant CYP2A6 alleles
@ast
A genetic polymorphism in coum ...... tion of variant CYP2A6 alleles
@en
A genetic polymorphism in coum ...... tion of variant CYP2A6 alleles
@nl
type
label
A genetic polymorphism in coum ...... tion of variant CYP2A6 alleles
@ast
A genetic polymorphism in coum ...... tion of variant CYP2A6 alleles
@en
A genetic polymorphism in coum ...... tion of variant CYP2A6 alleles
@nl
prefLabel
A genetic polymorphism in coum ...... tion of variant CYP2A6 alleles
@ast
A genetic polymorphism in coum ...... tion of variant CYP2A6 alleles
@en
A genetic polymorphism in coum ...... tion of variant CYP2A6 alleles
@nl
P2093
P2860
P1476
A genetic polymorphism in coum ...... tion of variant CYP2A6 alleles
@en
P2093
H Mohrenweiser
O Pelkonen
P Fernandez-Salguero
S Cholerton
S M Hoffman
P2860
P304
P407
P577
1995-09-01T00:00:00Z