WISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase - Test2 - elhamkhani - TriplyDB

WISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase

WISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase

http://www.wikidata.org/entity/Q24672918

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Wnt signaling protects 3T3-L1 preadipocytes from apoptosis through induction of insulin-like growth factors Association of the gene encoding wingless-type mammary tumor virus integration-site family member 5B (WNT5B) with type 2 diabetes CYR61 (CCN1) is essential for placental development and vascular integrity Early embryonic death in mice lacking the beta-catenin-binding protein Duplin WISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activity WISP1, a pro-mitogenic, pro-survival factor, mediates tumor necrosis factor-alpha (TNF-alpha)-stimulated cardiac fibroblast proliferation but inhibits TNF-alpha-induced cardiomyocyte death WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis WISP-1 is an osteoblastic regulator expressed during skeletal development and fracture repair Eyeing the Cyr61/CTGF/NOV (CCN) group of genes in development and diseases: highlights of their structural likenesses and functional dissimilarities Targeting disease through novel pathways of apoptosis and autophagy New Insights for Oxidative Stress and Diabetes Mellitus Novel applications of trophic factors, Wnt and WISP for neuronal repair and regeneration in metabolic disease Cellular transformation by cigarette smoke extract involves alteration of glycolysis and mitochondrial function in esophageal epithelial cells Sox2 induction by FGF and FGFR2 activating mutations inhibits Wnt signaling and osteoblast differentiation Neurofilament heavy polypeptide regulates the Akt-beta-catenin pathway in human esophageal squamous cell carcinoma Comprehensive functional characterization of cancer-testis antigens defines obligate participation in multiple hallmarks of cancer Transcriptome analysis using next generation sequencing reveals molecular signatures of diabetic retinopathy and efficacy of candidate drugs Differential analysis of two-dimension gel electrophoresis profiles from the normal-metaplasia-dysplasia-carcinoma tissue of human bronchial epithelium.The AP-1 transcription factor c-Jun prevents stress-imposed maladaptive remodeling of the heart.Screening for novel protein targets of indomethacin in HCT116 human colon cancer cells using proteomics Abnormal skeletal and cardiac development, cardiomyopathy, muscle atrophy and cataracts in mice with a targeted disruption of the Nov (Ccn3) gene Gene expression patterns in heterozygous Plk4 murine embryonic fibroblasts.The impact of human adipose tissue-derived stem cells on breast cancer cells: implications for cell-assisted lipotransfers in breast reconstruction.WNT1-inducible signaling pathway protein-1 activates diverse cell survival pathways and blocks doxorubicin-induced cardiomyocyte death The CCN proteins: important signaling mediators in stem cell differentiation and tumorigenesis.Overexpression of WISP-1 down-regulated motility and invasion of lung cancer cells through inhibition of Rac activation.Wnt activation is implicated in glioblastoma radioresistance.Transcriptional regulation of rod photoreceptor homeostasis revealed by in vivo NRL targetome analysis WISP1: Clinical insights for a proliferative and restorative member of the CCN family Novel avenues of drug discovery and biomarkers for diabetes mellitus.Overexpression of connective tissue growth factor WISP-1 in Chinese primary rectal cancer patients Herbal medicine Guan Chang Fu Fang enhances 5-fluorouracil cytotoxicity and affects drug-associated genes in human colorectal carcinoma cells.WISP-1 contributes to fractionated irradiation-induced radioresistance in esophageal carcinoma cell lines and mice.Targeting WNT, protein kinase B, and mitochondrial membrane integrity to foster cellular survival in the nervous system.Targeting WISP1 to sensitize esophageal squamous cell carcinoma to irradiation.Wnt1 inducible signaling pathway protein 1 (WISP1) blocks neurodegeneration through phosphoinositide 3 kinase/Akt1 and apoptotic mitochondrial signaling involving Bad, Bax, Bim, and Bcl-xL Cellular demise and inflammatory microglial activation during beta-amyloid toxicity are governed by Wnt1 and canonical signaling pathways.Clinico-Pathological Association of Delineated miRNAs in Uveal Melanoma with Monosomy 3/Disomy 3 Chromosomal Aberrations.WISP1 (CCN4) autoregulates its expression and nuclear trafficking of β-catenin during oxidant stress with limited effects upon neuronal autophagy.High expression of WISP-1 correlates with poor prognosis in pancreatic ductal adenocarcinoma.

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P2860

WISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase

http://www.wikidata.org/entity/Q24672918

description

2002 nî lūn-bûn

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2002 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2002 թվականի հունվարին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

WISP-1 attenuates p53-mediated ...... h activation of the Akt kinase

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WISP-1 attenuates p53-mediated ...... h activation of the Akt kinase

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WISP-1 attenuates p53-mediated ...... h activation of the Akt kinase

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type

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WISP-1 attenuates p53-mediated ...... h activation of the Akt kinase

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WISP-1 attenuates p53-mediated ...... h activation of the Akt kinase

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WISP-1 attenuates p53-mediated ...... h activation of the Akt kinase

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WISP-1 attenuates p53-mediated ...... h activation of the Akt kinase

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WISP-1 attenuates p53-mediated ...... h activation of the Akt kinase

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WISP-1 attenuates p53-mediated ...... h activation of the Akt kinase

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Genes & Development

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WISP-1 attenuates p53-mediated ...... h activation of the Akt kinase

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P2093

Arnold J Levine

http://www.w3.org/2001/XMLSchema#string

Daniel Besser

http://www.w3.org/2001/XMLSchema#string

Fei Su

http://www.w3.org/2001/XMLSchema#string

P2860

WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

Direct control of the Forkhead transcription factor AFX by protein kinase B

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

PUMA induces the rapid apoptosis of colorectal cancer cells

PUMA, a novel proapoptotic gene, is induced by p53

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

Fisp12/mouse connective tissue growth factor mediates endothelial cell adhesion and migration through integrin alphavbeta3, promotes endothelial cell survival, and induces angiogenesis in vivo

Multiple Bcl-2 family members demonstrate selective dimerizations with Bax

PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family

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46-57

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scholarly article

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3695062

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10.1101/GAD.942902

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1

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16

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Michael Overholtzer

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2002-01-01T00:00:00Z

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11576626

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P698

11782444

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P921

apoptotic process

P932

155313

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