Cbl-b positively regulates Btk-mediated activation of phospholipase C-gamma2 in B cells
about
Structural characterization of a novel Cbl phosphotyrosine recognition motif in the APS family of adapter proteinsCbl-c suppresses v-Src-induced transformation through ubiquitin-dependent protein degradationUbiquitylation as a Rheostat for TCR Signaling: From Targeted Approaches Toward Global ProfilingThe Cbl interactome and its functionsCbl-b is a novel physiologic regulator of glycoprotein VI-dependent platelet activation.Roles of E3 ubiquitin ligases in cell adhesion and migration.E3 ubiquitin ligase Cbl-b in innate and adaptive immunity.The chicken as a model for large-scale analysis of vertebrate gene function.Ig beta tyrosine residues contribute to the control of B cell receptor signaling by regulating receptor internalization.Control of the B cell-intrinsic tolerance programs by ubiquitin ligases Cbl and Cbl-b.The Syk-binding ubiquitin ligase c-Cbl mediates signaling-dependent B cell receptor ubiquitination and B cell receptor-mediated antigen processing and presentation.Loss of Cbl-PI3K interaction enhances osteoclast survival due to p21-Ras mediated PI3K activation independent of Cbl-bc-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signalling responses.Cbl-b negatively regulates B cell antigen receptor signaling in mature B cells through ubiquitination of the tyrosine kinase Syk.Loss of Cbl-b increases osteoclast bone-resorbing activity and induces osteopenia.Cbl proteins in platelet activation.Modulation of Immune Cell Functions by the E3 Ligase Cbl-b.Intracellular B Lymphocyte Signalling and the Regulation of Humoral Immunity and Autoimmunity.Binding of Cbl to a phospholipase Cgamma1-docking site on platelet-derived growth factor receptor beta provides a dual mechanism of negative regulation.ZFP521 contributes to pre-B-cell lymphomagenesis through modulation of the pre-B-cell receptor signaling pathway.Requirements for distinct steps of phospholipase Cgamma2 regulation, membrane-raft-dependent targeting and subsequent enzyme activation in B-cell signalling.The roles of Cbl-b and c-Cbl in insulin-stimulated glucose transport.
P2860
Q24297076-5780D435-18C3-4CDA-B94F-61142BC49643Q24301400-98E88FFA-4476-4A96-9F43-A954937F6F01Q26770849-C9177048-6A41-4281-933B-317085749627Q28277251-0336FD70-222A-422E-B7D0-173558F831FAQ33558284-92DE9904-569F-406A-A1C7-BC872A9BA7EAQ33781079-9AE5EF32-0C98-402B-9C25-DF4EFDCC4E3BQ33953086-A52A0812-7B7F-4C94-ADD4-CA62244DA150Q34174218-1D9A4A78-8440-490B-8082-8BF21342C0A1Q34544332-24F37BFC-4C50-4428-981F-DD46674DC768Q35940280-19FD16E5-6F19-414D-BC05-071B099BF513Q35956721-8BB0ED70-9499-42DA-95D9-F1366901A0A0Q36252532-76EA3CFE-568A-473E-B8B6-D2CB5B15B7B3Q36280423-952C8953-23DB-4607-A2BE-DF195CB63CD2Q36370786-77C103D9-77A9-499C-9BE1-09C2A67A82D9Q37230559-38555ED5-6538-4200-B587-6CAF939D0ADDQ38038873-76706175-FB51-4D27-A82D-9CBE70C6F36BQ38393275-57DCE18C-AF3D-49F8-BC19-F8CD10724FD3Q39272758-61E3F189-B49F-4B0F-84CE-F8D6B0C155F7Q40109529-6D26B281-30ED-4F60-B564-4D42AA0E429DQ40368934-54A17B24-FF87-4270-B508-E46DF32A9BB4Q40643436-ECDE4008-2C40-47BC-A349-B471CCCCEF0DQ42169339-517BD1BD-5B5A-4065-BC46-1731DE810002
P2860
Cbl-b positively regulates Btk-mediated activation of phospholipase C-gamma2 in B cells
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Cbl-b positively regulates Btk-mediated activation of phospholipase C-gamma2 in B cells
@ast
Cbl-b positively regulates Btk-mediated activation of phospholipase C-gamma2 in B cells
@en
Cbl-b positively regulates Btk-mediated activation of phospholipase C-gamma2 in B cells
@nl
type
label
Cbl-b positively regulates Btk-mediated activation of phospholipase C-gamma2 in B cells
@ast
Cbl-b positively regulates Btk-mediated activation of phospholipase C-gamma2 in B cells
@en
Cbl-b positively regulates Btk-mediated activation of phospholipase C-gamma2 in B cells
@nl
prefLabel
Cbl-b positively regulates Btk-mediated activation of phospholipase C-gamma2 in B cells
@ast
Cbl-b positively regulates Btk-mediated activation of phospholipase C-gamma2 in B cells
@en
Cbl-b positively regulates Btk-mediated activation of phospholipase C-gamma2 in B cells
@nl
P2093
P2860
P356
P1476
Cbl-b positively regulates Btk-mediated activation of phospholipase C-gamma2 in B cells
@en
P2093
Akito Maeda
Tadashi Yamamoto
Tetsuya Inazu
Tohru Tezuka
Tomoharu Yasuda
Tomohiro Kurosaki
Yuji Yamanashi
P2860
P356
10.1084/JEM.20020068
P407
P577
2002-07-01T00:00:00Z