Tristetraprolin and its family members can promote the cell-free deadenylation of AU-rich element-containing mRNAs by poly(A) ribonuclease
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The tandem CCCH zinc finger protein tristetraprolin and its relevance to cytokine mRNA turnover and arthritisAPLF (C2orf13) is a novel human protein involved in the cellular response to chromosomal DNA strand breaksMAPKAP kinase 2 phosphorylates tristetraprolin on in vivo sites including Ser178, a site required for 14-3-3 bindingNuclear deadenylation/polyadenylation factors regulate 3' processing in response to DNA damage.The zinc-finger antiviral protein recruits the RNA processing exosome to degrade the target mRNANot1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolinAU-rich elements and associated factors: are there unifying principles?CUG-BP binds to RNA substrates and recruits PARN deadenylaseThe ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase BHerpes simplex virus 1 induces cytoplasmic accumulation of TIA-1/TIAR and both synthesis and cytoplasmic accumulation of tristetraprolin, two cellular proteins that bind and destabilize AU-rich RNAsThe roles of TTP and BRF proteins in regulated mRNA decayA role for the eIF4E-binding protein 4E-T in P-body formation and mRNA decayDeterminants and implications of mRNA poly(A) tail size--does this protein make my tail look big?The 1.4-A crystal structure of the S. pombe Pop2p deadenylase subunit unveils the configuration of an active enzymeEarly recruitment of AU-rich element-containing mRNAs determines their cytosolic fate during iron deficiency.Regulation of ARE transcript 3' end processing by the yeast Cth2 mRNA decay factorPhosphorylation of human tristetraprolin in response to its interaction with the Cbl interacting protein CIN85MAPKAP kinase 2 blocks tristetraprolin-directed mRNA decay by inhibiting CAF1 deadenylase recruitmentProtor-2 interacts with tristetraprolin to regulate mRNA stability during stressRecruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1cAMP-dependent posttranscriptional regulation of steroidogenic acute regulatory (STAR) protein by the zinc finger protein ZFP36L1/TIS11bThe p38 MAPK pathway inhibits tristetraprolin-directed decay of interleukin-10 and pro-inflammatory mediator mRNAs in murine macrophagesMessenger RNA turnover in eukaryotes: pathways and enzymesAn integrated in silico approach to design specific inhibitors targeting human poly(a)-specific ribonucleaseCharacterization of DeltaN-Zfp36l2 mutant associated with arrest of early embryonic development and female infertilityDifferential expression and functional analysis of the tristetraprolin family during early differentiation of 3T3-L1 preadipocytesTristetraprolin inhibits poly(A)-tail synthesis in nuclear mRNA that contains AU-rich elements by interacting with poly(A)-binding protein nuclear 1Zfp36l3, a rodent X chromosome gene encoding a placenta-specific member of the Tristetraprolin family of CCCH tandem zinc finger proteinsChorioallantoic fusion defects and embryonic lethality resulting from disruption of Zfp36L1, a gene encoding a CCCH tandem zinc finger protein of the Tristetraprolin familyTargeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesisDeficiency of the placenta- and yolk sac-specific tristetraprolin family member ZFP36L3 identifies likely mRNA targets and an unexpected link to placental iron metabolismCysteine and histidine shuffling: mixing and matching cysteine and histidine residues in zinc finger proteins to afford different folds and function.Inhibition of tristetraprolin deadenylation by poly(A) binding protein.Identification of the anti-inflammatory protein tristetraprolin as a hyperphosphorylated protein by mass spectrometry and site-directed mutagenesisGenome-wide analysis of CCCH zinc finger family in Arabidopsis and rice.The Fragment HMGA2-sh-3p20 from HMGA2 mRNA 3'UTR Promotes the Growth of Hepatoma Cells by Upregulating HMGA2.Identification of a major phosphopeptide in human tristetraprolin by phosphopeptide mapping and mass spectrometry.To polyadenylate or to deadenylate: that is the question.Comprehensive analysis of CCCH zinc finger family in poplar (Populus trichocarpa).Expression, purification, and biochemical characterization of the antiinflammatory tristetraprolin: a zinc-dependent mRNA binding protein affected by posttranslational modifications.
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P2860
Tristetraprolin and its family members can promote the cell-free deadenylation of AU-rich element-containing mRNAs by poly(A) ribonuclease
description
2003 nî lūn-bûn
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2003 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունիսին հրատարակված գիտական հոդված
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2003年の論文
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2003年論文
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2003年論文
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2003年論文
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2003年論文
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2003年論文
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2003年论文
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Tristetraprolin and its family ...... mRNAs by poly(A) ribonuclease
@ast
Tristetraprolin and its family ...... mRNAs by poly(A) ribonuclease
@en
Tristetraprolin and its family ...... mRNAs by poly(A) ribonuclease
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type
label
Tristetraprolin and its family ...... mRNAs by poly(A) ribonuclease
@ast
Tristetraprolin and its family ...... mRNAs by poly(A) ribonuclease
@en
Tristetraprolin and its family ...... mRNAs by poly(A) ribonuclease
@nl
prefLabel
Tristetraprolin and its family ...... mRNAs by poly(A) ribonuclease
@ast
Tristetraprolin and its family ...... mRNAs by poly(A) ribonuclease
@en
Tristetraprolin and its family ...... mRNAs by poly(A) ribonuclease
@nl
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Tristetraprolin and its family ...... mRNAs by poly(A) ribonuclease
@en
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Elizabeth A Kennington
Perry J Blackshear
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10.1128/MCB.23.11.3798-3812.2003
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2003-06-01T00:00:00Z