Identification of an adaptor-associated kinase, AAK1, as a regulator of clathrin-mediated endocytosis - Test2 - elhamkhani - TriplyDB

Identification of an adaptor-associated kinase, AAK1, as a regulator of clathrin-mediated endocytosis

Identification of an adaptor-associated kinase, AAK1, as a regulator of clathrin-mediated endocytosis

http://www.wikidata.org/entity/Q24673296

about

Pulmonary proteome and protein networks in response to the herbicide paraquat in rats Functional dissection of an AP-2 beta2 appendage-binding sequence within the autosomal recessive hypercholesterolemia protein The adaptor-associated kinase 1, AAK1, is a positive regulator of the Notch pathway A novel AAK1 splice variant functions at multiple steps of the endocytic pathway A CD317/tetherin-RICH2 complex plays a critical role in the organization of the subapical actin cytoskeleton in polarized epithelial cells The clavesin family, neuron-specific lipid- and clathrin-binding Sec14 proteins regulating lysosomal morphology Identification of novel ATP13A2 interactors and their role in α-synuclein misfolding and toxicity A large-scale conformational change couples membrane recruitment to cargo binding in the AP2 clathrin adaptor complex aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb.Unlocking the mysteries of Na+-K+-ATPase endocytosis: phosphorylation is the key Phosphorylation of the AP2 mu subunit by AAK1 mediates high affinity binding to membrane protein sorting signals Enthoprotin: a novel clathrin-associated protein identified through subcellular proteomics Clathrin-dependent association of CVAK104 with endosomes and the trans-Golgi network.Differential requirements for AP-2 in clathrin-mediated endocytosis The clathrin adaptor complexes as a paradigm for membrane-associated allostery Beta2-adaptin binds actopaxin and regulates cell spreading, migration and matrix degradation Mechanism for the Selective Interaction of C-terminal Eps15 Homology Domain Proteins with Specific Asn-Pro-Phe-containing Partners Dynamic phosphoregulation of the cortical actin cytoskeleton and endocytic machinery revealed by real-time chemical genetic analysis.Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy AAK1-mediated micro2 phosphorylation is stimulated by assembled clathrin CK2 and GAK/auxilin2 are major protein kinases in clathrin-coated vesicles Dual engagement regulation of protein interactions with the AP-2 adaptor alpha appendage Neonatal lethality in knockout mice expressing the kinase-dead form of the gefitinib target GAK is caused by pulmonary dysfunction SRC-mediated phosphorylation of dynamin and cortactin regulates the "constitutive" endocytosis of transferrin Chemical genetic identification of NDR1/2 kinase substrates AAK1 and Rabin8 Uncovers their roles in dendrite arborization and spine development Kinome analysis of receptor-induced phosphorylation in human natural killer cells Natively unfolded domains in endocytosis: hooks, lines and linkers.Adapting for endocytosis: roles for endocytic sorting adaptors in directing neural development.PARtitioning numb.Scd5p mediates phosphoregulation of actin and endocytosis by the type 1 phosphatase Glc7p in yeast Endocytic accessory proteins are functionally distinguished by their differential effects on the maturation of clathrin-coated pits.Αvβ3-integrin-mediated adhesion is regulated through an AAK1L- and EHD3-dependent rapid-recycling pathway The clathrin-binding motif and the J-domain of Drosophila Auxilin are essential for facilitating Notch ligand endocytosis.Lineage-specific proteins essential for endocytosis in trypanosomes.Identification of novel recognition motifs and regulatory targets for the yeast actin-regulating kinase Prk1p Chronic lymphocytic leukemia cells induce changes in gene expression of CD4 and CD8 T cells.Epidermal growth factor-dependent phosphorylation of the GGA3 adaptor protein regulates its recruitment to membranes.Clathrin adaptor AP-2 is essential for early embryonal development.Phosphorylation by Dyrk1A of clathrin coated vesicle-associated proteins: identification of the substrate proteins and the effects of phosphorylation.Cargo recognition in clathrin-mediated endocytosis

P2860

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P2860

Identification of an adaptor-associated kinase, AAK1, as a regulator of clathrin-mediated endocytosis

http://www.wikidata.org/entity/Q24673296

description

2002 nî lūn-bûn

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2002 թուականի Մարտին հրատարակուած գիտական յօդուած

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2002 թվականի մարտին հրատարակված գիտական հոդված

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Identification of an adaptor-a ...... clathrin-mediated endocytosis

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Identification of an adaptor-a ...... clathrin-mediated endocytosis

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Identification of an adaptor-a ...... clathrin-mediated endocytosis

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Identification of an adaptor-a ...... clathrin-mediated endocytosis

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Identification of an adaptor-a ...... clathrin-mediated endocytosis

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Identification of an adaptor-a ...... clathrin-mediated endocytosis

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Identification of an adaptor-a ...... clathrin-mediated endocytosis

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Identification of an adaptor-a ...... clathrin-mediated endocytosis

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Identification of an adaptor-a ...... clathrin-mediated endocytosis

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Journal of Cell Biology

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Identification of an adaptor-a ...... clathrin-mediated endocytosis

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Sandra L Schmid

http://www.w3.org/2001/XMLSchema#string

Sean D Conner

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P2860

Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module

Regulatory interactions in the recognition of endocytic sorting signals by AP-2 complexes.

The 50 kDa protein subunit of assembly polypeptide (AP) AP-2 adaptor from clathrin-coated vesicles is phosphorylated on threonine-156 by AP-1 and a soluble AP50 kinase which co-purifies with the assembly polypeptides

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

Targeting signals and subunit interactions in coated vesicle adaptor complexes

Phosphorylation of the AP2 mu subunit by AAK1 mediates high affinity binding to membrane protein sorting signals

A structural explanation for the binding of multiple ligands by the alpha-adaptin appendage domain

Novel protein kinases Ark1p and Prk1p associate with and regulate the cortical actin cytoskeleton in budding yeast.

Pan1p, yeast eps15, functions as a multivalent adaptor that coordinates protein-protein interactions essential for endocytosis

Regulation of the actin cytoskeleton organization in yeast by a novel serine/threonine kinase Prk1p

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2587892

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10.1083/JCB.200108123

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5

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156

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11486187

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11877461

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2173317

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