Pharmacology of nociceptin and its receptor: a novel therapeutic target
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Small-molecule agonists and antagonists of the opioid receptor-like receptor (ORL1, NOP): ligand-based analysis of structural factors influencing intrinsic activity at NOPPharmacological characterization of the novel nociceptin/orphanin FQ receptor ligand, ZP120: in vitro and in vivo studies in micePharmacological profiles of a novel opioid receptor-like1 (ORL(1)) receptor antagonist, JTC-801Pathophysiology, Clinical Importance, and Management of Neurogenic Lower Urinary Tract Dysfunction Caused by Suprasacral Spinal Cord InjuryThe Useage of Opioids and their Adverse Effects in Gastrointestinal Practice: A ReviewFunctional plasticity of the N/OFQ-NOP receptor system determines analgesic properties of NOP receptor agonistsPeptide and nonpeptide ligands for the nociceptin/orphanin FQ receptor ORL1: research tools and potential therapeutic agentsPharmacological properties of nociceptin/orphanin FQ-induced stimulation and inhibition of cyclic AMP formation in distinct layers of rat olfactory bulbActions of nociceptin/orphanin FQ and other prepronociceptin products on rat rostral ventromedial medulla neurons in vitroNociceptin/orphanin FQ exacerbates excitotoxic white-matter lesions in the murine neonatal brainInhibitory action of nociceptin/orphanin FQ on functionally different thalamic neurons in urethane-anaesthetized ratsNociceptin inhibits cough in the guinea-pig by activation of ORL(1) receptorsControl of glutamate and GABA release by nociceptin/orphanin FQ in the rat lateral amygdalaActivation of nociceptin/orphanin FQ peptide receptors disrupts visual but not auditory sensorimotor gating in BALB/cByJ mice: comparison to dopamine receptor agonists.Memory-specific temporal profiles of gene expression in the hippocampusBinding of GTPgamma[35S] is regulated by GDP and receptor activation. Studies with the nociceptin/orphanin FQ receptor.Effects of nociceptin/orphanin FQ on rats with cathartic colonLow utility of plasma Nociceptin/orphanin FQ in the diagnosis of hepatocellular carcinoma.Swim stress enhances nociceptin/orphanin FQ-induced inhibition of rat dorsal raphe nucleus activity in vivo and in vitro: role of corticotropin releasing factor.Pharmacological profile of the NOP agonist and cough suppressing agent SCH 486757 (8-[Bis(2-Chlorophenyl)Methyl]-3-(2-Pyrimidinyl)-8-Azabicyclo[3.2.1]Octan-3-Ol) in preclinical models.A combined pharmacological and genetic approach to investigate the role of orphanin FQ in learning and memory.The nociceptive and anti-nociceptive effects of bee venom injection and therapy: a double-edged swordAcute and chronic antiparkinsonian effects of the novel nociceptin/orphanin FQ receptor antagonist NiK-21273 in comparison with SB-612111.Pharmacological profile of nociceptin/orphanin FQ receptors.Drug dependence: neuropharmacology and management.Solution structure of nociceptin peptides.Comparison of the ORL1 receptor-mediated inhibition of noradrenaline release in human and rat neocortical slicesOrphanin FQ inhibits capsaicin-induced thermal nociception in monkeys by activation of peripheral ORL1 receptors[Nphe1,Arg14,Lys15]nociceptin-NH2, a novel potent and selective antagonist of the nociceptin/orphanin FQ receptor.Central injections of nocistatin or its C-terminal hexapeptide exert anxiogenic-like effect on behaviour of mice in the plus-maze testDirect and indirect inhibition by nociceptin/orphanin FQ on noradrenaline release from rodent cerebral cortex in vitroPharmacological profiles of presynaptic nociceptin/orphanin FQ receptors modulating 5-hydroxytryptamine and noradrenaline release in the rat neocortexActivation of the nociceptin/orphanin FQ receptor reduces bronchoconstriction and microvascular leakage in a rabbit model of gastroesophageal reflux.Nociceptin/orphanin FQ: actions within the brain.Orphanin FQ/nociceptin interacts with the basolateral amygdala noradrenergic system in memory consolidation.Activation of nociceptin opioid peptide (NOP) receptor impairs contextual fear learning in mice through glutamatergic mechanisms.In vitro and in vivo studies on UFP-112, a novel potent and long lasting agonist selective for the nociceptin/orphanin FQ receptorRoles of μ-opioid receptors and nociceptin/orphanin FQ peptide receptors in buprenorphine-induced physiological responses in primates.The therapeutic potential of nociceptin/orphanin FQ receptor agonists as analgesics without abuse liability.Nociceptin/Orphanin FQ Receptor Structure, Signaling, Ligands, Functions, and Interactions with Opioid Systems.
P2860
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P2860
Pharmacology of nociceptin and its receptor: a novel therapeutic target
description
2000 nî lūn-bûn
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2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2000 թվականի ապրիլին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
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name
Pharmacology of nociceptin and its receptor: a novel therapeutic target
@ast
Pharmacology of nociceptin and its receptor: a novel therapeutic target
@en
Pharmacology of nociceptin and its receptor: a novel therapeutic target
@nl
type
label
Pharmacology of nociceptin and its receptor: a novel therapeutic target
@ast
Pharmacology of nociceptin and its receptor: a novel therapeutic target
@en
Pharmacology of nociceptin and its receptor: a novel therapeutic target
@nl
prefLabel
Pharmacology of nociceptin and its receptor: a novel therapeutic target
@ast
Pharmacology of nociceptin and its receptor: a novel therapeutic target
@en
Pharmacology of nociceptin and its receptor: a novel therapeutic target
@nl
P2093
P2860
P3181
P356
P1476
Pharmacology of nociceptin and its receptor: a novel therapeutic target
@en
P2093
P2860
P304
P3181
P356
10.1038/SJ.BJP.0703219
P407
P577
2000-04-01T00:00:00Z