Dominant-negative mutants of human MxA protein: domains in the carboxy-terminal moiety are important for oligomerization and antiviral activity
about
Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infectionMxA GTPase blocks reporter gene expression of reconstituted Thogoto virus ribonucleoprotein complexesAntiviral actions of interferonsThe guanylate binding protein-1 GTPase controls the invasive and angiogenic capability of endothelial cells through inhibition of MMP-1 expressionInterferon-alpha/beta receptor-mediated selective induction of a gene cluster by CpG oligodeoxynucleotide 2006Protective roles of grass carp Ctenopharyngodon idella Mx isoforms against grass carp reovirusInterferon-induced human MxA GTPase blocks nuclear import of Thogoto virus nucleocapsids.Influenza A virus strains differ in sensitivity to the antiviral action of Mx-GTPaseThe nucleoprotein of newly emerged H7N9 influenza A virus harbors a unique motif conferring resistance to antiviral human MxA.Interferon-inducible protein Mx1 inhibits influenza virus by interfering with functional viral ribonucleoprotein complex assemblyPandemic influenza A viruses escape from restriction by human MxA through adaptive mutations in the nucleoprotein.Inhibition of tumor cell motility by the interferon-inducible GTPase MxAThe cytoplasmic location of chicken mx is not the determining factor for its lack of antiviral activityDynamin GTPase domain mutants block endocytic vesicle formation at morphologically distinct stages.Antivirally active MxA protein sequesters La Crosse virus nucleocapsid protein into perinuclear complexes.Transfer of the amino-terminal nuclear envelope targeting domain of human MX2 converts MX1 into an HIV-1 resistance factorStalk domain of the dynamin-like MxA GTPase protein mediates membrane binding and liposome tubulation via the unstructured L4 loopRole of nucleotide binding and GTPase domain dimerization in dynamin-like myxovirus resistance protein A for GTPase activation and antiviral activity.Mx1 and Mx2 key antiviral proteins are surprisingly lost in toothed whalesDeep mutational scanning identifies sites in influenza nucleoprotein that affect viral inhibition by MxAOligomerization Requirements for MX2-Mediated Suppression of HIV-1 InfectionEvolution-guided identification of antiviral specificity determinants in the broadly acting interferon-induced innate immunity factor MxA.Antiviral determinants of rat Mx GTPases map to the carboxy-terminal half.Mx Is Not Responsible for the Antiviral Activity of Interferon-α against Japanese Encephalitis Virus.Mx proteins: antiviral gatekeepers that restrain the uninvited.Oligomerization and GTP-binding Requirements of MxA for Viral Target Recognition and Antiviral Activity against Influenza A Virus.A monomeric GTPase-negative MxA mutant with antiviral activity.Asparagine 631 variants of the chicken Mx protein do not inhibit influenza virus replication in primary chicken embryo fibroblasts or in vitro surrogate assays.MxA Mediates SUMO-Induced Resistance to Vesicular Stomatitis Virus.Mx is dispensable for interferon-mediated resistance of chicken cells against influenza A virus.The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii.Effects of allelic variations in the human Myxovirus resistance protein A on its antiviral activity.The 125th Lys and 145th Thr Amino Acids in the GTPase Domain of Goose Mx Confer Its Antiviral Activity against the Tembusu Virus
P2860
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P2860
Dominant-negative mutants of human MxA protein: domains in the carboxy-terminal moiety are important for oligomerization and antiviral activity
description
1997 nî lūn-bûn
@nan
1997 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Dominant-negative mutants of h ...... ization and antiviral activity
@ast
Dominant-negative mutants of h ...... ization and antiviral activity
@en
Dominant-negative mutants of h ...... ization and antiviral activity
@nl
type
label
Dominant-negative mutants of h ...... ization and antiviral activity
@ast
Dominant-negative mutants of h ...... ization and antiviral activity
@en
Dominant-negative mutants of h ...... ization and antiviral activity
@nl
prefLabel
Dominant-negative mutants of h ...... ization and antiviral activity
@ast
Dominant-negative mutants of h ...... ization and antiviral activity
@en
Dominant-negative mutants of h ...... ization and antiviral activity
@nl
P2093
P2860
P1433
P1476
Dominant-negative mutants of h ...... ization and antiviral activity
@en
P2093
P2860
P304
P407
P577
1997-04-01T00:00:00Z