Oncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cells - Test2 - elhamkhani - TriplyDB

Oncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cells

Oncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cells

http://www.wikidata.org/entity/Q24678591

about

hTid-1, a human DnaJ protein, modulates the interferon signaling pathway The human homologue of the yeast proteins Skb1 and Hsl7p interacts with Jak kinases and contains protein methyltransferase activity.Socs-1 inhibits TEL-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation.Id1 is a common downstream target of oncogenic tyrosine kinases in leukemic cells Preclinical studies of novel targeted therapies.Inhibition of cytokines and JAK-STAT activation by distinct signaling pathways.JAK2-STAT5B pathway and osteoblast differentiation.Identification of molecular vulnerabilities in human multiple myeloma cells by RNA interference lethality screening of the druggable genome Multiple myeloma: increasing evidence for a multistep transformation process.Proteasome inhibitor PS-341 abrogates IL-6 triggered signaling cascades via caspase-dependent downregulation of gp130 in multiple myeloma.RAFTK/PYK2-dependent and -independent apoptosis in multiple myeloma cells.

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P2860

Oncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cells

http://www.wikidata.org/entity/Q24678591

description

1995 nî lūn-bûn

@nan

1995 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1995 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

1995年の論文

@ja

1995年論文

@yue

1995年論文

@zh-hant

1995年論文

@zh-hk

1995年論文

@zh-mo

1995年論文

@zh-tw

1995年论文

@wuu

name

Oncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cells

@ast

Oncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cells

@en

Oncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cells

@nl

type

label

Oncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cells

@ast

Oncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cells

@en

Oncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cells

@nl

prefLabel

Oncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cells

@ast

Oncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cells

@en

Oncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cells

@nl

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Journal of Experimental Medicine

P1476

Oncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cells

@en

P2093

A Ogata

http://www.w3.org/2001/XMLSchema#string

D Chauhan

http://www.w3.org/2001/XMLSchema#string

D Frank

http://www.w3.org/2001/XMLSchema#string

D W Kufe

http://www.w3.org/2001/XMLSchema#string

K C Anderson

http://www.w3.org/2001/XMLSchema#string

M Urashima

http://www.w3.org/2001/XMLSchema#string

N Malik

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S M Kharbanda

http://www.w3.org/2001/XMLSchema#string

P2860

Mitogen-activated protein kinases and ribosomal S6 protein kinases are involved in signaling pathways shared by interleukin-11, interleukin-6, leukemia inhibitory factor, and oncostatin M in mouse 3T3-L1 cells

LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6

Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family

Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130

A protein tyrosine kinase in the interferon alpha/beta signaling pathway

Oncostatin M induces tyrosine phosphorylation in endothelial cells and activation of p62yes tyrosine kinase

Activation of the MAP kinase pathway by the protein kinase raf

Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

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1801-6

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scholarly article

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10.1084/JEM.182.6.1801

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6

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182

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1995-12-01T00:00:00Z

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277393729

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7500025

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2192257

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