CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation - Test2 - elhamkhani - TriplyDB

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

http://www.wikidata.org/entity/Q24678846

about

CTLA-4 blockade: therapeutic potential in cancer treatments State of the science: an update on renal cell carcinoma Constitutive and inducible expression of b7 family of ligands by human airway epithelial cells Interaction of CTLA-4 with AP50, a clathrin-coated pit adaptor protein T helper cell activation and human retroviral pathogenesis Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation CTLA-4 ligation blocks CD28-dependent T cell activation Multiple functions for CD28 and cytotoxic T lymphocyte antigen-4 during different phases of T cell responses: implications for arthritis and autoimmune diseases The effects of chemotherapeutics on cellular metabolism and consequent immune recognition Tumor-associated antigens identified by mRNA expression profiling as tumor rejection epitopes Lack of correlation between the levels of soluble cytotoxic T-lymphocyte associated antigen-4 (CTLA-4) and the CT-60 genotypes Immunologic aspect of ovarian cancer and p53 as tumor antigen.Immunobiology of hepatocarcinogenesis: Ways to go or almost there?Melanoma immunotherapy dominates the field The immune microenvironment in Hodgkin lymphoma: T cells, B cells, and immune checkpoints Immunotherapy for cancer in the central nervous system: Current and future directions New strategies in immunotherapy for non-small cell lung cancer Melanoma: oncogenic drivers and the immune system CTLA-4 and PD-1 Pathways: Similarities, Differences, and Implications of Their Inhibition Predictive factors for immunotherapy in melanoma Advances in immunotherapy for treatment of lung cancer Immune Effects of Chemotherapy, Radiation, and Targeted Therapy and Opportunities for Combination With Immunotherapy T Cells: Soldiers and Spies--The Surveillance and Control of Effector T Cells by Regulatory T Cells Induced regulatory T cells: mechanisms of conversion and suppressive potential Nucleic Acid Aptamers: An Emerging Tool for Biotechnology and Biomedical Sensing Therapeutic vaccines as a promising treatment modality against prostate cancer: rationale and recent advances Combining radiation and immunotherapy: a new systemic therapy for solid tumors?Review of immune-related adverse events in prostate cancer patients treated with ipilimumab: MD Anderson experience Immunotherapy strategies for multiple myeloma: the present and the future A bispecific protein capable of engaging CTLA-4 and MHCII protects non-obese diabetic mice from autoimmune diabetes Personalized treatment of Sézary syndrome by targeting a novel CTLA4:CD28 fusion.Unraveling the Role of Allo-Antibodies and Transplant Injury Diacylglycerol Kinases (DGKs): Novel Targets for Improving T Cell Activity in Cancer Epigenetic Therapeutics: A New Weapon in the War Against Cancer Immunoregulation in Fungal Diseases The Impact of Chemotherapy, Radiation and Epigenetic Modifiers in Cancer Cell Expression of Immune Inhibitory and Stimulatory Molecules and Anti-Tumor Efficacy Immune checkpoint therapy for pancreatic cancer PD-1 and PD-L1 antibodies for melanoma Costimulation of T cells A cellular calculus for signal integration by T cells

P2860

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P2860

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

http://www.wikidata.org/entity/Q24678846

description

1995 nî lūn-bûn

@nan

1995 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

1995 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

1995年の論文

@ja

1995年論文

@yue

1995年論文

@zh-hant

1995年論文

@zh-hk

1995年論文

@zh-mo

1995年論文

@zh-tw

1995年论文

@wuu

name

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

@ast

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

@en

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

@nl

type

label

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

@ast

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

@en

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

@nl

prefLabel

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

@ast

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

@en

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

@nl

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P1433

Journal of Experimental Medicine

P1476

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

@en

P2093

J P Allison

http://www.w3.org/2001/XMLSchema#string

M F Krummel

http://www.w3.org/2001/XMLSchema#string

P2860

T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif

Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling

CTLA-4 binding to the lipid kinase phosphatidylinositol 3-kinase in T cells

Stimulation of CD28 triggers an association between CD28 and phosphatidylinositol 3-kinase in Jurkat T cells

SH2 domains recognize specific phosphopeptide sequences

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

CTLA-4 can function as a negative regulator of T cell activation

The role of the CD28 receptor during T cell responses to antigen

CTLA-4 and CD28 activated lymphocyte molecules are closely related in both mouse and human as to sequence, message expression, gene structure, and chromosomal location

A new member of the immunoglobulin superfamily--CTLA-4

P304

459-65

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scholarly article

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1046554

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10.1084/JEM.182.2.459

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2

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182

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James P. Allison

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1995-08-01T00:00:00Z

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15656253

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7543139

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2192127

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