CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature - Test2 - elhamkhani - TriplyDB

CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature

CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature

http://www.wikidata.org/entity/Q24681010

about

Opposing roles of CXCR4 and CXCR7 in breast cancer metastasis.Carboxy-terminus of CXCR7 regulates receptor localization and function Ubiquitination of CXCR7 controls receptor trafficking CXCL12 / CXCR4 / CXCR7 chemokine axis and cancer progression Diversity and Inter-Connections in the CXCR4 Chemokine Receptor/Ligand Family: Molecular Perspectives Chemokine-Derived Peptides: Novel Antimicrobial and Antineoplasic Agents CXC chemokines and chemokine receptors in gastric cancer: from basic findings towards therapeutic targeting Chemokine receptor-specific antibodies in cancer immunotherapy: achievements and challenges Expression of the chemokine receptor CXCR7 in CXCR4-expressing human 143B osteosarcoma cells enhances lung metastasis of intratibial xenografts in SCID mice CXCR7 functions as a scavenger for CXCL12 and CXCL11 Intercohort gene expression co-analysis reveals chemokine receptors as prognostic indicators in Ewing's sarcoma CXCR7 protein expression in human adult brain and differentiated neurons Protein structure prediction: when is it useful?CXCR4, but not CXCR7, discriminates metastatic behavior in non-small cell lung cancer cells CXC chemokines in cancer angiogenesis and metastases CXCR4 drives the metastatic phenotype in breast cancer through induction of CXCR2 and activation of MEK and PI3K pathways Elucidating a key component of cancer metastasis: CXCL12 (SDF-1α) binding to CXCR4.Secreted CXCL12 (SDF-1) forms dimers under physiological conditions.The CXCL12gamma chemokine displays unprecedented structural and functional properties that make it a paradigm of chemoattractant proteins CXCR4 expression in papillary thyroid carcinoma: induction by nitric oxide and correlation with lymph node metastasis.Differences in the tumor microenvironment between African-American and European-American breast cancer patients Tumour-initiating capacity is independent of epithelial-mesenchymal transition status in breast cancer cell lines.Silencing of CXCR4 and CXCR7 expression by RNA interference suppresses human endometrial carcinoma growth in vivo CXCR7/CXCL12 axis is involved in lymph node and liver metastasis of gastric carcinoma.Microfluidic source-sink model reveals effects of biophysically distinct CXCL12 isoforms in breast cancer chemotaxis CXCL12 modulation of CXCR4 and CXCR7 activity in human glioblastoma stem-like cells and regulation of the tumor microenvironment.COX-2 and prostaglandin EP3/EP4 signaling regulate the tumor stromal proangiogenic microenvironment via CXCL12-CXCR4 chemokine systems.CXCR7 controls competition for recruitment of β-arrestin 2 in cells expressing both CXCR4 and CXCR7.CXCR7 expression disrupts endothelial cell homeostasis and causes ligand-dependent invasion.Inhibition of androgen receptor promotes CXC-chemokine receptor 7-mediated prostate cancer cell survival.Chemokine receptor CXCR7 regulates the invasion, angiogenesis and tumor growth of human hepatocellular carcinoma cells.C-X-C motif chemokine 12/C-X-C chemokine receptor type 7 signaling regulates breast cancer growth and metastasis by modulating the tumor microenvironment.GPCRs and cancer Effects of the chemokine CXCL12 and combined internalization of its receptors CXCR4 and CXCR7 in human MCF-7 breast cancer cells.Synthesis and investigation of a radioiodinated F3 peptide analog as a SPECT tumor imaging radioligand The role of chemoattractant receptors in shaping the tumor microenvironment.C-terminal region of EBNA-2 determines the superior transforming ability of type 1 Epstein-Barr virus by enhanced gene regulation of LMP-1 and CXCR7.Overlapping and distinct role of CXCR7-SDF-1/ITAC and CXCR4-SDF-1 axes in regulating metastatic behavior of human rhabdomyosarcomas Microfluidic platform for chemotaxis in gradients formed by CXCL12 source-sink cells.Transfer, imaging, and analysis plate for facile handling of 384 hanging drop 3D tissue spheroids

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CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature

http://www.wikidata.org/entity/Q24681010

description

2007 nî lūn-bûn

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2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2007年の論文

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Aidas Nasevicius

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Alnawaz Rehemtulla

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Bretton C Summers

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Celina G Kleer

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Gary D Luker

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Jeffrey J Essner

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Kathryn E Luker

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Mahaveer S Bhojani

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Maureen C Howard

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Rob Berahovich

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P2860

Involvement of chemokine receptors in breast cancer metastasis

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development

Overexpression of CCR7 mRNA in nonsmall cell lung cancer: correlation with lymph node metastasis

Cancer and the chemokine network

CXCR4 regulates growth of both primary and metastatic breast cancer

HHV8-encoded vMIP-I selectively engages chemokine receptor CCR8. Agonist and antagonist profiles of viral chemokines

Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors

Molecular characterization of the tumor microenvironment in breast cancer.

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