Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53
about
Structural features of human histone acetyltransferase p300 and its complex with p53VRK1 chromatin kinase phosphorylates H2AX and is required for foci formation induced by DNA damageStructural and functional characterization of an atypical activation domain in erythroid Kruppel-like factor (EKLF)Mapping the interactions of the p53 transactivation domain with the KIX domain of CBPStructural basis for p300 Taz2-p53 TAD1 binding and modulation by phosphorylationCooperative regulation of p53 by modulation of ternary complex formation with CBP/p300 and HDM2Regulation by phosphorylation of the relative affinities of the N-terminal transactivation domains of p53 for p300 domains and Mdm2The multifaceted role of lysine acetylation in cancer: prognostic biomarker and therapeutic targetAsparaginase treatment side-effects may be due to genes with homopolymeric Asn codons (Review-Hypothesis)Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domainsStructure of the Taz2 domain of p300: insights into ligand bindingRas signaling requires dynamic properties of Ets1 for phosphorylation-enhanced binding to coactivator CBPStructure of the p53 Transactivation Domain in Complex with the Nuclear Receptor Coactivator Binding Domain of CREB Binding ProteinStructure of p300 bound to MEF2 on DNA reveals a mechanism of enhanceosome assemblyStructures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitmentStructural and Functional Characterization of a Complex between the Acidic Transactivation Domain of EBNA2 and the Tfb1/p62 Subunit of TFIIHMechanism of Mediator recruitment by tandem Gcn4 activation domains and three Gal11 activator-binding domainsMolecular targets in urothelial cancer: detection, treatment, and animal models of bladder cancerSpecific recognition of p53 tetramers by peptides derived from p53 interacting proteinsAdaptive patterns in the p53 protein sequence of the hypoxia- and cancer-tolerant blind mole rat SpalaxThe F-box protein beta-TrCp1/Fbw1a interacts with p300 to enhance beta-catenin transcriptional activity.Two distinct motifs within the p53 transactivation domain bind to the Taz2 domain of p300 and are differentially affected by phosphorylationEP300 contributes to high-altitude adaptation in Tibetans by regulating nitric oxide production.Activating transcription factor 3 activates p53 by preventing E6-associated protein from binding to E6.The origins and evolution of the p53 family of genes.Posttranslational modification of p53: cooperative integrators of functionPathological unfoldomics of uncontrolled chaos: intrinsically disordered proteins and human diseasesTranscriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition.MDM2 recruitment of lysine methyltransferases regulates p53 transcriptional outputGraded enhancement of p53 binding to CREB-binding protein (CBP) by multisite phosphorylation.Shared structural features of the 9aaTAD family in complex with CBP.Molecular basis for modulation of the p53 target selectivity by KLF4.The 9aaTAD Transactivation Domains: From Gal4 to p53.Structural characterization of interactions between transactivation domain 1 of the p65 subunit of NF-κB and transcription regulatory factors.Global conformational selection and local induced fit for the recognition between intrinsic disordered p53 and CBPAdvancements in the development of HIF-1α-activated protein switches for use in enzyme prodrug therapy.Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression.Mutant p53: one name, many proteins.Functional advantages of dynamic protein disorder.The HTLV-1-encoded protein HBZ directly inhibits the acetyl transferase activity of p300/CBP.
P2860
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P2860
Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53
description
2007 nî lūn-bûn
@nan
2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Four domains of p300 each bind ...... nsactivation subdomains of p53
@ast
Four domains of p300 each bind ...... nsactivation subdomains of p53
@en
Four domains of p300 each bind ...... nsactivation subdomains of p53
@nl
type
label
Four domains of p300 each bind ...... nsactivation subdomains of p53
@ast
Four domains of p300 each bind ...... nsactivation subdomains of p53
@en
Four domains of p300 each bind ...... nsactivation subdomains of p53
@nl
prefLabel
Four domains of p300 each bind ...... nsactivation subdomains of p53
@ast
Four domains of p300 each bind ...... nsactivation subdomains of p53
@en
Four domains of p300 each bind ...... nsactivation subdomains of p53
@nl
P2093
P2860
P3181
P356
P1476
Four domains of p300 each bind ...... nsactivation subdomains of p53
@en
P2093
Daniel P Teufel
Mark Bycroft
Stefan M Freund
P2860
P304
P3181
P356
10.1073/PNAS.0702010104
P407
P50
P577
2007-04-24T00:00:00Z