Human monoclonal antibodies against anthrax lethal factor and protective antigen act independently to protect against Bacillus anthracis infection and enhance endogenous immunity to anthrax
about
Anthrax prophylaxis: recent advances and future directionsMonoclonal Antibody Combinations that Present Synergistic Neutralizing Activity: A Platform for Next-Generation Anti-Toxin DrugsCrystal Structure of the Engineered Neutralizing Antibody M18 Complexed to Domain 4 of the Anthrax Protective AntigenCD4+ T Cells Targeting Dominant and Cryptic Epitopes from Bacillus anthracis Lethal FactorIsolation and chimerization of a highly neutralizing antibody conferring passive protection against lethal Bacillus anthracis infectionAn overview of anthrax infection including the recently identified form of disease in injection drug usersAnthrax vaccination strategiesMonoclonal antibody therapies against anthraxHuman anti-plague monoclonal antibodies protect mice from Yersinia pestis in a bubonic plague modelAnthrax LFn-PA Hybrid Antigens: Biochemistry, Immunogenicity, and Protection Against Lethal Ames Spore Challenge in Rabbits.Select human anthrax protective antigen epitope-specific antibodies provide protection from lethal toxin challenge.Towards a human oral vaccine for anthrax: the utility of a Salmonella Typhi Ty21a-based prime-boost immunization strategyA novel mechanism for antibody-based anthrax toxin neutralization: inhibition of prepore-to-pore conversion.An anthrax subunit vaccine candidate based on protective regions of Bacillus anthracis protective antigen and lethal factor.Cathelicidin administration protects mice from Bacillus anthracis spore challengeRapid vaccination using an acetalated dextran microparticulate subunit vaccine confers protection against triplicate challenge by bacillus anthracis.Mapping the epitopes of a neutralizing antibody fragment directed against the lethal factor of Bacillus anthracis and cross-reacting with the homologous edema factorAnthrax vaccination induced anti-lethal factor IgG: fine specificity and neutralizing capacity.Antibodies against anthrax: mechanisms of action and clinical applications.Development of an in vitro potency assay for anti-anthrax lethal toxin neutralizing antibodiesA Novel Chimeric Anti-PA Neutralizing Antibody for Postexposure Prophylaxis and Treatment of Anthrax.Analysis of epitope information related to Bacillus anthracis and Clostridium botulinum.Human monoclonal antibodies generated following vaccination with AVA provide neutralization by blocking furin cleavage but not by preventing oligomerizationMonoclonal antibodies and toxins--a perspective on function and isotype.Bacillus anthracis cell wall produces injurious inflammation but paradoxically decreases the lethality of anthrax lethal toxin in a rat model.MHC class II and non-MHC class II genes differentially influence humoral immunity to Bacillus anthracis lethal factor and protective antigen.In vivo efficacy of beta-cyclodextrin derivatives against anthrax lethal toxinCharacterization of the native form of anthrax lethal factor for use in the toxin neutralization assay.Sequential B-cell epitopes of Bacillus anthracis lethal factor bind lethal toxin-neutralizing antibodiesAnti-infective antibodies: a novel tool to prevent and treat nosocomial diseases.Dendritic cell targeting of Bacillus anthracis protective antigen expressed by Lactobacillus acidophilus protects mice from lethal challengeAnti-toxin antibodies in prophylaxis and treatment of inhalation anthrax.Synthetic peptide vaccine targeting a cryptic neutralizing epitope in domain 2 of Bacillus anthracis protective antigen.Potent neutralization of anthrax edema toxin by a humanized monoclonal antibody that competes with calmodulin for edema factor binding.Novel chimpanzee/human monoclonal antibodies that neutralize anthrax lethal factor, and evidence for possible synergy with anti-protective antigen antibody.The major neutralizing antibody responses to recombinant anthrax lethal and edema factors are directed to non-cross-reactive epitopes.A heterologous helper T-cell epitope enhances the immunogenicity of a multiple-antigenic-peptide vaccine targeting the cryptic loop-neutralizing determinant of Bacillus anthracis protective antigen.Predictive models and correlates of protection for testing biodefence vaccines.Anthrax vaccines: present status and future prospects.Fusion protein of Delta 27LFn and EFn has the potential as a novel anthrax toxin inhibitor.
P2860
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P2860
Human monoclonal antibodies against anthrax lethal factor and protective antigen act independently to protect against Bacillus anthracis infection and enhance endogenous immunity to anthrax
description
2007 nî lūn-bûn
@nan
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
name
Human monoclonal antibodies ag ...... endogenous immunity to anthrax
@ast
Human monoclonal antibodies ag ...... endogenous immunity to anthrax
@en
Human monoclonal antibodies ag ...... endogenous immunity to anthrax
@nl
type
label
Human monoclonal antibodies ag ...... endogenous immunity to anthrax
@ast
Human monoclonal antibodies ag ...... endogenous immunity to anthrax
@en
Human monoclonal antibodies ag ...... endogenous immunity to anthrax
@nl
prefLabel
Human monoclonal antibodies ag ...... endogenous immunity to anthrax
@ast
Human monoclonal antibodies ag ...... endogenous immunity to anthrax
@en
Human monoclonal antibodies ag ...... endogenous immunity to anthrax
@nl
P2093
P2860
P356
P1476
Human monoclonal antibodies ag ...... endogenous immunity to anthrax
@en
P2093
Alfred Mateczun
Chris S LeButt
Darrell Galloway
E Diane Williamson
Hans Westra
Helen C Flick-Smith
Herman Groen
Les W J Baillie
Mark T Albrecht
P2860
P304
P356
10.1128/IAI.00261-07
P407
P577
2007-11-01T00:00:00Z