NPAT expression is regulated by E2F and is essential for cell cycle progression - Test2 - elhamkhani - TriplyDB

NPAT expression is regulated by E2F and is essential for cell cycle progression

NPAT expression is regulated by E2F and is essential for cell cycle progression

http://www.wikidata.org/entity/Q24684949

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HiNF-P directly links the cyclin E/CDK2/p220NPAT pathway to histone H4 gene regulation at the G1/S phase cell cycle transition.Deficiency of the zinc finger protein ZPR1 causes defects in transcription and cell cycle progression A subset of replication-dependent histone mRNAs are expressed as polyadenylated RNAs in terminally differentiated tissues The histone genes cluster in Rhynchosciara americana and its transcription profile in salivary glands during larval development Fidelity of histone gene regulation is obligatory for genome replication and stability.CBP/p300 and SIRT1 are involved in transcriptional regulation of S-phase specific histone genes.HES-1 inhibits 17beta-estradiol and heregulin-beta1-mediated upregulation of E2F-1.A whole-genome RNA interference screen for human cell factors affecting myxoma virus replication Cyclin D2 and the CDK substrate p220(NPAT) are required for self-renewal of human embryonic stem cells.Genome-wide RNAi screening identifies host restriction factors critical for in vivo AAV transduction Transcriptional activation of the histone nuclear factor P (HiNF-P) gene by HiNF-P and its cyclin E/CDK2 responsive co-factor p220NPAT defines a novel autoregulatory loop at the G1/S phase transition.p53 checkpoint ablation exacerbates the phenotype of Hinfp dependent histone H4 deficiency.Transcriptional activation of histone genes requires NPAT-dependent recruitment of TRRAP-Tip60 complex to histone promoters during the G1/S phase transition.Interaction of Heat Shock Protein Cpn10 with the Cyclin E/Cdk2 Substrate Nuclear Protein Ataxia-Telangiectasia (NPAT) Is Involved in Regulating Histone Transcription Integration of the metabolic/redox state, histone gene switching, DNA replication and S-phase progression by moonlighting metabolic enzymes.The control of histone gene expression.Genome-wide screen of cell-cycle regulators in normal and tumor cells identifies a differential response to nucleosome depletion.Genetic variants associated with mosaic Y chromosome loss highlight cell cycle genes and overlap with cancer susceptibility.Human T Lymphotropic Virus Type 1 protein Tax reduces histone levels.Nuclear reorganization of mammalian DNA synthesis prior to cell cycle exit.DNA damage induces downregulation of histone gene expression through the G1 checkpoint pathway.The histone gene transcription factor HiNF-P stabilizes its cell cycle regulatory co-activator p220NPAT.Common Expression Quantitative Trait Loci Shared by Histone Genes.Cyclin E2 is the predominant E-cyclin associated with NPAT in breast cancer cells Induced G1 cell-cycle arrest controls replication-dependent histone mRNA 3' end processing through p21, NPAT and CDK9.Maternal expression and early induction of histone gene transcription factor Hinfp sustains development in pre-implantation embryos.

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P2860

NPAT expression is regulated by E2F and is essential for cell cycle progression

http://www.wikidata.org/entity/Q24684949

description

2003 nî lūn-bûn

@nan

2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի ապրիլին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

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2003年论文

@wuu

name

NPAT expression is regulated by E2F and is essential for cell cycle progression

@ast

NPAT expression is regulated by E2F and is essential for cell cycle progression

@en

NPAT expression is regulated by E2F and is essential for cell cycle progression

@nl

type

label

NPAT expression is regulated by E2F and is essential for cell cycle progression

@ast

NPAT expression is regulated by E2F and is essential for cell cycle progression

@en

NPAT expression is regulated by E2F and is essential for cell cycle progression

@nl

prefLabel

NPAT expression is regulated by E2F and is essential for cell cycle progression

@ast

NPAT expression is regulated by E2F and is essential for cell cycle progression

@en

NPAT expression is regulated by E2F and is essential for cell cycle progression

@nl

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MCB.23.8.2821-2833.2003

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Molecular and Cellular Biology

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NPAT expression is regulated by E2F and is essential for cell cycle progression

@en

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Claire Attwooll

http://www.w3.org/2001/XMLSchema#string

Guang Gao

http://www.w3.org/2001/XMLSchema#string

Jiyong Zhao

http://www.w3.org/2001/XMLSchema#string

Karina Burkard

http://www.w3.org/2001/XMLSchema#string

Marie Classon

http://www.w3.org/2001/XMLSchema#string

Masashi Sagara

http://www.w3.org/2001/XMLSchema#string

Takashi Imai

http://www.w3.org/2001/XMLSchema#string

P2860

Cell cycle-regulated phosphorylation of p220(NPAT) by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription

A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells

CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase

NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription

Expression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entry

Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression

E2f3 is critical for normal cellular proliferation

E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints

Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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2821-33

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scholarly article

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3061341

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10.1128/MCB.23.8.2821-2833.2003

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8

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23

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Adrian P Bracken

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2003-04-01T00:00:00Z

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12665581

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152552

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