Sodium channel beta1 and beta3 subunits associate with neurofascin through their extracellular immunoglobulin-like domain
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Modulation of the cardiac sodium channel Nav1.5 by fibroblast growth factor homologous factor 1BAnkyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segmentsMechanisms of sodium channel clustering and its influence on axonal impulse conductionCrystal Structure and Molecular Imaging of the Nav Channel 3 Subunit Indicates a Trimeric AssemblyOn the multiple roles of the voltage gated sodium channel β1 subunit in genetic diseasesSodium channel β subunits: emerging targets in channelopathiesStructural requirements for interaction of sodium channel beta 1 subunits with ankyrinSodium channel beta1 subunit-mediated modulation of Nav1.2 currents and cell surface density is dependent on interactions with contactin and ankyrinA glial signal consisting of gliomedin and NrCAM clusters axonal Na+ channels during the formation of nodes of RanvierInteraction of the Nav1.2a subunit of the voltage-dependent sodium channel with nodal ankyrinG. In vitro mapping of the interacting domains and association in synaptosomesAnalysis of non-canonical fibroblast growth factor receptor 1 (FGFR1) interaction reveals regulatory and activating domains of neurofascinNodes of Ranvier and axon initial segments are ankyrin G-dependent domains that assemble by distinct mechanismsTyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytesStructure and function of voltage-gated sodium channels at atomic resolution.The VGL-Chanome: A Protein Superfamily Specialized for Electrical Signaling and Ionic HomeostasisReduced sodium channel density, altered voltage dependence of inactivation, and increased susceptibility to seizures in mice lacking sodium channel beta 2-subunits.Localization and targeting of voltage-dependent ion channels in mammalian central neurons.Axon initial segment dysfunction in a mouse model of genetic epilepsy with febrile seizures plus.Identification of NCAM-binding peptides promoting neurite outgrowth via a heterotrimeric G-protein-coupled pathway.Organization and maintenance of molecular domains in myelinated axonsMild Traumatic Brain Injury Evokes Pyramidal Neuron Axon Initial Segment Plasticity and Diffuse Presynaptic Inhibitory Terminal Loss.Developing nodes of Ranvier are defined by ankyrin-G clustering and are independent of paranodal axoglial adhesion.Identification of a conserved ankyrin-binding motif in the family of sodium channel alpha subunits.The sodium channel β1 subunit mediates outgrowth of neurite-like processes on breast cancer cells and promotes tumour growth and metastasis.The cell adhesion molecule neurofascin stabilizes axo-axonic GABAergic terminals at the axon initial segment.Na Channel β Subunits: Overachievers of the Ion Channel Family.Fibronectin type III-like domains of neurofascin-186 protein mediate gliomedin binding and its clustering at the developing nodes of Ranvier.Functional identification of pathogenic autoantibody responses in patients with multiple sclerosis.Secreted gliomedin is a perinodal matrix component of peripheral nerves.An ankyrinG-binding motif is necessary and sufficient for targeting Nav1.6 sodium channels to axon initial segments and nodes of RanvierNeurofascin as a novel target for autoantibody-mediated axonal injuryAssembly and maintenance of nodes of ranvier rely on distinct sources of proteins and targeting mechanisms.Tandem gramicidin channels cross-linked by streptavidin.The immunoglobulin domain of the sodium channel β3 subunit contains a surface-localized disulfide bond that is required for homophilic bindingAnkyrinG is required for maintenance of the axon initial segment and neuronal polarity.Trafficking and cellular distribution of voltage-gated sodium channels.Postsynaptic density-93 clusters Kv1 channels at axon initial segments independently of Caspr2.The voltage-gated Na+ channel beta3 subunit does not mediate trans homophilic cell adhesion or associate with the cell adhesion molecule contactinThe mouse F3/contactin glycoprotein: structural features, functional properties and developmental significance of its regulated expression.Maternal neurofascin-specific autoantibodies bind to structures of the fetal nervous system during pregnancy, but have no long term effect on development in the rat.
P2860
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P2860
Sodium channel beta1 and beta3 subunits associate with neurofascin through their extracellular immunoglobulin-like domain
description
2001 nî lūn-bûn
@nan
2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Sodium channel beta1 and beta3 ...... lar immunoglobulin-like domain
@ast
Sodium channel beta1 and beta3 ...... lar immunoglobulin-like domain
@en
Sodium channel beta1 and beta3 ...... lar immunoglobulin-like domain
@nl
type
label
Sodium channel beta1 and beta3 ...... lar immunoglobulin-like domain
@ast
Sodium channel beta1 and beta3 ...... lar immunoglobulin-like domain
@en
Sodium channel beta1 and beta3 ...... lar immunoglobulin-like domain
@nl
prefLabel
Sodium channel beta1 and beta3 ...... lar immunoglobulin-like domain
@ast
Sodium channel beta1 and beta3 ...... lar immunoglobulin-like domain
@en
Sodium channel beta1 and beta3 ...... lar immunoglobulin-like domain
@nl
P2093
P2860
P356
P1476
Sodium channel beta1 and beta3 ...... lar immunoglobulin-like domain
@en
P2093
C F Ratcliffe
R E Westenbroek
W A Catterall
P2860
P304
P356
10.1083/JCB.200102086
P407
P577
2001-07-23T00:00:00Z