Different conformations of nascent polypeptides during translocation across the ER membrane
about
The Brichos domain of prosurfactant protein C can hold and fold a transmembrane segmentX-ray structure of a protein-conducting channelHigh-resolution structure of a BRICHOS domain and its implications for anti-amyloid chaperone activity on lung surfactant protein C.The Brichos domain-containing C-terminal part of pro-surfactant protein C binds to an unfolded poly-val transmembrane segmentMulti-omic data integration enables discovery of hidden biological regularities.Control of translocation through the Sec61 translocon by nascent polypeptide structure within the ribosome.A folding zone in the ribosomal exit tunnel for Kv1.3 helix formation.Positive charges of translocating polypeptide chain retrieve an upstream marginal hydrophobic segment from the endoplasmic reticulum lumen to the translocon.Cotranslational Protein Folding inside the Ribosome Exit Tunnel.Ribosome exit tunnel can entropically stabilize alpha-helices.Free energy of nascent-chain folding in the translocon.Stepwise insertion and inversion of a type II signal anchor sequence in the ribosome-Sec61 translocon complex.Polytopic membrane protein folding at L17 in the ribosome tunnel initiates cyclical changes at the transloconAlteration of CFTR transmembrane span integration by disease-causing mutations.Glycosylation of prion strains in transmissible spongiform encephalopathies.A little help from my friends: quality control of presecretory proteins in bacteriaVersatility of the endoplasmic reticulum protein folding factory.Formation of transmembrane helices in vivo--is hydrophobicity all that matters?Electrostatics in the ribosomal tunnel modulate chain elongation rates.Tertiary interactions within the ribosomal exit tunnel.Transmembrane segments form tertiary hairpins in the folding vestibule of the ribosome.Lectin chaperones help direct the maturation of glycoproteins in the endoplasmic reticulum.Membrane protein integration into the endoplasmic reticulum.BRICHOS domain associated with lung fibrosis, dementia and cancer--a chaperone that prevents amyloid fibril formation?Viroporins, Examples of the Two-Stage Membrane Protein Folding Model.NMR Investigation of Structures of G-protein Coupled Receptor Folding Intermediates.The α-helical structure of prodomains promotes translocation of intrinsically disordered neuropeptide hormones into the endoplasmic reticulum.Structural features within the nascent chain regulate alternative targeting of secretory proteins to mitochondria.alpha-Helical domains promote translocation of intrinsically disordered polypeptides into the endoplasmic reticulumFolding and Intramembraneous BRICHOS Binding of the Prosurfactant Protein C Transmembrane SegmentPolypeptide binding specificities of Saccharomyces cerevisiae oligosaccharyltransferase accessory proteins Ost3p and Ost6p.Early encounters of a nascent membrane protein: specificity and timing of contacts inside and outside the ribosome.The anthrax toxin channel: a barrel of LFs.Protein folding taking shape. Workshop on molecular chaperones.A biphasic pulling force acts on transmembrane helices during translocon-mediated membrane integration.Protein unfolding is not a prerequisite for endoplasmic reticulum-to-cytosol dislocation.Folding zones inside the ribosomal exit tunnel.The Sec61/SecY complex is inherently deficient in translocating intrinsically disordered proteins.
P2860
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P2860
Different conformations of nascent polypeptides during translocation across the ER membrane
description
2000 nî lūn-bûn
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2000 թուականին հրատարակուած գիտական յօդուած
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2000 թվականին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
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name
Different conformations of nas ...... ocation across the ER membrane
@ast
Different conformations of nas ...... ocation across the ER membrane
@en
Different conformations of nas ...... ocation across the ER membrane
@nl
type
label
Different conformations of nas ...... ocation across the ER membrane
@ast
Different conformations of nas ...... ocation across the ER membrane
@en
Different conformations of nas ...... ocation across the ER membrane
@nl
prefLabel
Different conformations of nas ...... ocation across the ER membrane
@ast
Different conformations of nas ...... ocation across the ER membrane
@en
Different conformations of nas ...... ocation across the ER membrane
@nl
P2860
P3181
P356
P1433
P1476
Different conformations of nas ...... ocation across the ER membrane
@en
P2093
P2860
P2888
P3181
P356
10.1186/1471-2121-1-3
P407
P577
2000-01-01T00:00:00Z
P5875
P6179
1029252800