cDNA array-CGH profiling identifies genomic alterations specific to stage and MYCN-amplification in neuroblastoma
about
Identification of amplified and highly expressed genes in amplicons of the T-cell line huT78 detected by cDNA microarray CGHSpanning the genomics era: the vital role of a single institution biorepository for childhood cancer research over a decadeMolecular pathogenesis of peripheral neuroblastic tumorsA novel technique for measuring variations in DNA copy-number: competitive genomic polymerase chain reaction.High-resolution array copy number analyses for detection of deletion, gain, amplification and copy-neutral LOH in primary neuroblastoma tumors: four cases of homozygous deletions of the CDKN2A gene.Array-based gene expression, CGH and tissue data defines a 12q24 gain in neuroblastic tumors with prognostic implication.Global genomic and proteomic analysis identifies biological pathways related to high-risk neuroblastoma.High-risk neuroblastoma tumors with 11q-deletion display a poor prognostic, chromosome instability phenotype with later onset.The polyamine metabolism genes ornithine decarboxylase and antizyme 2 predict aggressive behavior in neuroblastomas with and without MYCN amplificationDetection of somatic mutations by high-resolution DNA melting (HRM) analysis in multiple cancers.Clinical characteristics and outcome of patients with neuroblastoma presenting genomic amplification of loci other than MYCN.Myc proteins as therapeutic targets.Age dependence of tumor genetics in unfavorable neuroblastoma: arrayCGH profiles of 34 consecutive cases, using a Swedish 25-year neuroblastoma cohort for validation.Frequent promoter hypermethylation of RASSF1A and CASP8 in neuroblastomaA unique cytogenetic abnormality, t(2;7)(p13.1;p21.3), in a Philadelphia-positive chronic myeloid leukemiaArray-based comparative genomic hybridization in clinical diagnosis.Genes proximal and distal to MYCN are highly expressed in human neuroblastoma as visualized by comparative expressed sequence hybridizationWhole chromosome alterations predict survival in high-risk neuroblastoma without MYCN amplification.Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastomaThe MYCN oncogene is a direct target of miR-34a.Presence of 1q gain and absence of 7p gain are new predictors of local or metastatic relapse in localized resectable neuroblastoma.A small subunit processome protein promotes cancer by altering translation.The neuroblastoma and ganglion components of nodular ganglioneuroblastoma are genetically similar: evidence against separate clonal origins.
P2860
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P2860
cDNA array-CGH profiling identifies genomic alterations specific to stage and MYCN-amplification in neuroblastoma
description
2004 nî lūn-bûn
@nan
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
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2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
cDNA array-CGH profiling ident ...... amplification in neuroblastoma
@ast
cDNA array-CGH profiling ident ...... amplification in neuroblastoma
@en
cDNA array-CGH profiling ident ...... amplification in neuroblastoma
@nl
type
label
cDNA array-CGH profiling ident ...... amplification in neuroblastoma
@ast
cDNA array-CGH profiling ident ...... amplification in neuroblastoma
@en
cDNA array-CGH profiling ident ...... amplification in neuroblastoma
@nl
prefLabel
cDNA array-CGH profiling ident ...... amplification in neuroblastoma
@ast
cDNA array-CGH profiling ident ...... amplification in neuroblastoma
@en
cDNA array-CGH profiling ident ...... amplification in neuroblastoma
@nl
P2093
P2860
P356
P1433
P1476
cDNA array-CGH profiling ident ...... amplification in neuroblastoma
@en
P2093
Alexei L Krasnoselsky
Braden T Greer
Chang-Gue Son
Craig C Whiteford
Daniel Catchpoole
Frank Berthold
Frank Westermann
Javed Khan
Manfred Schwab
P2860
P2888
P356
10.1186/1471-2164-5-70
P407
P577
2004-09-20T00:00:00Z
P5875
P6179
1050987597