Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant
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Pathogen recognition and activation of the innate immune response in zebrafishIMMUNOLOGY OF TUBERCULOSISA newly discovered mycobacterial pathogen isolated from laboratory colonies of Xenopus species with lethal infections produces a novel form of mycolactone, the Mycobacterium ulcerans macrolide toxinStructure and function of the complex formed by the tuberculosis virulence factors CFP-10 and ESAT-6ESX-1 secreted virulence factors are recognized by multiple cytosolic AAA ATPases in pathogenic mycobacteriaHost-pathogen interactions made transparent with the zebrafish modelA model 450 million years in the making: zebrafish and vertebrate immunityThe Zebrafish Breathes New Life into the Study of TuberculosisFit for consumption: zebrafish as a model for tuberculosisLeptospira interrogans stably infects zebrafish embryos, altering phagocyte behavior and homing to specific tissuesHost-detrimental role of Esx-1-mediated inflammasome activation in mycobacterial infectionA high-throughput screen for tuberculosis progressionComparison of four different crystal forms of theMycobacterium tuberculosisESX-1 secreted protein regulator EspRProtection and pathology in TB: learning from the zebrafish modelControl of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoPMycobacterium tuberculosis MycP1 protease plays a dual role in regulation of ESX-1 secretion and virulenceA non-RD1 gene cluster is required for Snm secretion in Mycobacterium tuberculosisSecreted transcription factor controls Mycobacterium tuberculosis virulenceA mycobacterium ESX-1-secreted virulence factor with unique requirements for exportMutually dependent secretion of proteins required for mycobacterial virulence.Mycobacteria counteract a TLR-mediated nitrosative defense mechanism in a zebrafish infection modelPseudomonas aeruginosa Type III secretion system interacts with phagocytes to modulate systemic infection of zebrafish embryosThe role of the granuloma in expansion and dissemination of early tuberculous infection.Tumor necrosis factor signaling mediates resistance to mycobacteria by inhibiting bacterial growth and macrophage death.Evaluation of the pathogenesis and treatment of Mycobacterium marinum infection in zebrafish.Interception of host angiogenic signalling limits mycobacterial growth.Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions.Polar localization of virulence-related Esx-1 secretion in mycobacteria.Signal regulatory protein alpha (SIRPalpha) cells in the adaptive response to ESAT-6/CFP-10 protein of tuberculous mycobacteria.A novel ESX-1 locus reveals that surface-associated ESX-1 substrates mediate virulence in Mycobacterium marinum.An attenuated Mycobacterium tuberculosis clinical strain with a defect in ESX-1 secretion induces minimal host immune responses and pathologyDendritic cells in chronic mycobacterial granulomas restrict local anti-bacterial T cell response in a murine model.CD36 deficiency attenuates experimental mycobacterial infection.ESX1-dependent fractalkine mediates chemotaxis and Mycobacterium tuberculosis infection in humans.A Mycobacterium marinum TesA mutant defective for major cell wall-associated lipids is highly attenuated in Dictyostelium discoideum and zebrafish embryos.A peptide fragment from the human COX3 protein disrupts association of Mycobacterium tuberculosis virulence proteins ESAT-6 and CFP10, inhibits mycobacterial growth and mounts protective immune responseA three-hybrid system to probe in vivo protein-protein interactions: application to the essential proteins of the RD1 complex of M. tuberculosis.Modeling tuberculous meningitis in zebrafish using Mycobacterium marinum.Direct detection of bacterial protein secretion using whole colony proteomics.Role of pore-forming toxins in bacterial infectious diseases.
P2860
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P2860
Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant
@ast
Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant
@en
Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant
@nl
type
label
Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant
@ast
Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant
@en
Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant
@nl
prefLabel
Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant
@ast
Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant
@en
Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant
@nl
P2093
P2860
P3181
P1433
P1476
Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant
@en
P2093
Dana Beery
David R Sherman
Hannah E Volkman
Hilary Clay
Jennifer C W Chang
P2860
P3181
P356
10.1371/JOURNAL.PBIO.0020367
P407
P577
2004-11-01T00:00:00Z