Extended base pair complementarity between U1 snRNA and the 5' splice site does not inhibit splicing in higher eukaryotes, but rather increases 5' splice site recognition
about
The hepatitis B virus PRE contains a splicing regulatory element.A targeted bypass screen identifies Ynl187p, Prp42p, Snu71p, and Cbp80p for stable U1 snRNP/Pre-mRNA interaction.Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility geneNonsense-mediated decay enables intron gain in Drosophila.Excessive RNA splicing and inhibition of HIV-1 replication induced by modified U1 small nuclear RNAs.Cryptic splice site usage in exon 7 of the human fibrinogen Bbeta-chain gene is regulated by a naturally silent SF2/ASF binding site within this exonGene therapeutic approach using mutation-adapted U1 snRNA to correct a RPGR splice defect in patient-derived cells.The strength of the HIV-1 3' splice sites affects Rev function.Defective splicing, disease and therapy: searching for master checkpoints in exon definition.A DNA damage signal activates and derepresses exon inclusion in Drosophila TAF1 alternative splicingPick one, but be quick: 5' splice sites and the problems of too many choices.Noncanonical registers and base pairs in human 5' splice-site selection.Succession of splicing regulatory elements determines cryptic 5΄ss functionality.Factors affecting splicing strength of yeast genes.Limited complementarity between U1 snRNA and a retroviral 5' splice site permits its attenuation via RNA secondary structure.A genome-wide transcriptome and translatome analysis of Arabidopsis transposons identifies a unique and conserved genome expression strategy for Ty1/Copia retroelements.hnRNP L and hnRNP A1 induce extended U1 snRNA interactions with an exon to repress spliceosome assembly.Widespread recognition of 5' splice sites by noncanonical base-pairing to U1 snRNA involving bulged nucleotides.Aberrant 5' splice sites in human disease genes: mutation pattern, nucleotide structure and comparison of computational tools that predict their utilization.Cryptic splicing sites are differentially utilized in vivo.Establishment of a chimeric, replication-deficient influenza A virus vector by modulation of splicing efficiency.U1-like snRNAs lacking complementarity to canonical 5' splice sites.The conserved AU dinucleotide at the 5' end of nascent U1 snRNA is optimized for the interaction with nuclear cap-binding-complex.Low U1 snRNP dependence at the NF1 exon 29 donor splice site.RNA Structure Design Improves Activity and Specificity of trans-Splicing-Triggered Cell Death in a Suicide Gene Therapy Approach.
P2860
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P2860
Extended base pair complementarity between U1 snRNA and the 5' splice site does not inhibit splicing in higher eukaryotes, but rather increases 5' splice site recognition
description
2005 nî lūn-bûn
@nan
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Extended base pair complementa ...... ses 5' splice site recognition
@ast
Extended base pair complementa ...... ses 5' splice site recognition
@en
Extended base pair complementa ...... ses 5' splice site recognition
@nl
type
label
Extended base pair complementa ...... ses 5' splice site recognition
@ast
Extended base pair complementa ...... ses 5' splice site recognition
@en
Extended base pair complementa ...... ses 5' splice site recognition
@nl
prefLabel
Extended base pair complementa ...... ses 5' splice site recognition
@ast
Extended base pair complementa ...... ses 5' splice site recognition
@en
Extended base pair complementa ...... ses 5' splice site recognition
@nl
P2093
P2860
P356
P1476
Extended base pair complementa ...... ses 5' splice site recognition
@en
P2093
Carolin Konermann
Heiner Schaal
Marcel Freund
Marianne Otte
P2860
P304
P356
10.1093/NAR/GKI824
P407
P577
2005-09-09T00:00:00Z