8-oxoguanine incorporation into DNA repeats in vitro and mismatch recognition by MutSalpha.
about
Base excision repair and cancerDNA mismatch repair in eukaryotes and bacteriaMethotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair gene MSH2Critical amino acids in human DNA polymerases eta and kappa involved in erroneous incorporation of oxidized nucleotides.DNA polymerases as potential therapeutic targets for cancers deficient in the DNA mismatch repair proteins MSH2 or MLH1Inactivation of the DNA repair genes mutS, mutL or the anti-recombination gene mutS2 leads to activation of vitamin B1 biosynthesis genes.DNA mismatch repair and oxidative DNA damage: implications for cancer biology and treatment.Salvage of oxidized guanine derivatives in the (2'-deoxy)ribonucleotide pool as source of mutations in DNA.Cytosine-based nucleoside analogs are selectively lethal to DNA mismatch repair-deficient tumour cells by enhancing levels of intracellular oxidative stress.Restoration of mismatch repair functions in human cell line Nalm-6, which has high efficiency for gene targeting.Error-free bypass of 2-hydroxyadenine by human DNA polymerase lambda with Proliferating Cell Nuclear Antigen and Replication Protein A in different sequence contexts.Replication of 2-hydroxyadenine-containing DNA and recognition by human MutSalpha.Klenow Fragment Discriminates against the Incorporation of the Hyperoxidized dGTP Lesion Spiroiminodihydantoin into DNA.DNA repair of oxidative DNA damage in human carcinogenesis: potential application for cancer risk assessment and preventionOxidized dNTPs and the OGG1 and MUTYH DNA glycosylases combine to induce CAG/CTG repeat instability.The polymerase eta translesion synthesis DNA polymerase acts independently of the mismatch repair system to limit mutagenesis caused by 7,8-dihydro-8-oxoguanine in yeast.Sources of extracellular, oxidatively-modified DNA lesions: implications for their measurement in urine.MUTYH mediates the toxicity of combined DNA 6-thioguanine and UVA radiation.DNA repair and the origins of urinary oxidized 2'-deoxyribonucleosides.
P2860
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P2860
8-oxoguanine incorporation into DNA repeats in vitro and mismatch recognition by MutSalpha.
description
2005 nî lūn-bûn
@nan
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
name
8-oxoguanine incorporation int ...... match recognition by MutSalpha
@nl
8-oxoguanine incorporation int ...... atch recognition by MutSalpha.
@ast
8-oxoguanine incorporation int ...... atch recognition by MutSalpha.
@en
type
label
8-oxoguanine incorporation int ...... match recognition by MutSalpha
@nl
8-oxoguanine incorporation int ...... atch recognition by MutSalpha.
@ast
8-oxoguanine incorporation int ...... atch recognition by MutSalpha.
@en
prefLabel
8-oxoguanine incorporation int ...... match recognition by MutSalpha
@nl
8-oxoguanine incorporation int ...... atch recognition by MutSalpha.
@ast
8-oxoguanine incorporation int ...... atch recognition by MutSalpha.
@en
P2093
P2860
P356
P1476
8-oxoguanine incorporation int ...... atch recognition by MutSalpha.
@en
P2093
Filomena Mazzei
Flavia Barone
Giovanni Maga
Margherita Bignami
Peter Karran
Peter Macpherson
P2860
P304
P356
10.1093/NAR/GKI813
P407
P577
2005-09-20T00:00:00Z