Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion.
about
Separate roles of structured and unstructured regions of Y-family DNA polymerasesA new anti conformation for N-(deoxyguanosin-8-yl)-2-acetylaminofluorene (AAF-dG) allows Watson-Crick pairing in the Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4).A rescue act: Translesion DNA synthesis past N(2) -deoxyguanosine adductsHydrogen bonding of 7,8-dihydro-8-oxodeoxyguanosine with a charged residue in the little finger domain determines miscoding events in Sulfolobus solfataricus DNA polymerase Dpo4Versatility of Y-family Sulfolobus solfataricus DNA Polymerase Dpo4 in Translesion Synthesis Past Bulky N2-Alkylguanine AdductsImpact of Conformational Heterogeneity of OxoG Lesions and Their Pairing Partners on Bypass Fidelity by Y Family PolymerasesStructure of the Human Rev1–DNA–dNTP Ternary ComplexStructure of Human DNA Polymerase κ Inserting dATP Opposite an 8-OxoG DNA LesionStructural and Functional Elucidation of the Mechanism Promoting Error-prone Synthesis by Human DNA Polymerase Opposite the 7,8-Dihydro-8-oxo-2'-deoxyguanosine AdductStructure-Function Relationships in Miscoding by Sulfolobus solfataricus DNA Polymerase Dpo4: GUANINE N2,N2-DIMETHYL SUBSTITUTION PRODUCES INACTIVE AND MISCODING POLYMERASE COMPLEXESMolecular Basis of Transcriptional Mutagenesis at 8-OxoguanineMechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4Replication through an abasic DNA lesion: structural basis for adenine selectivityStructural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4Mutagenic conformation of 8-oxo-7,8-dihydro-2′-dGTP in the confines of a DNA polymerase active siteStructural Basis for Error-free Replication of Oxidatively Damaged DNA by Yeast DNA Polymerase ηUnique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iotaRole of Human DNA Polymerase κ in Extension Opposite from a cis–syn Thymine DimerThe Y-Family DNA Polymerase Dpo4 Uses a Template Slippage Mechanism To Create Single-Base DeletionsImplications for Damage Recognition during Dpo4-Mediated Mutagenic Bypass of m1G and m3C LesionsBypass of Aflatoxin B 1 Adducts by the Sulfolobus solfataricus DNA Polymerase IVDNA polymerase minor groove interactions modulate mutagenic bypass of a templating 8-oxoguanine lesionHuman DNA Polymerase η Is Pre-Aligned for dNTP Binding and CatalysisDeletion of Ogg1 DNA glycosylase results in telomere base damage and length alteration in yeast.An overview of Y-Family DNA polymerases and a case study of human DNA polymerase ηA water-mediated and substrate-assisted catalytic mechanism for Sulfolobus solfataricus DNA polymerase IV.Mutagenic nucleotide incorporation and hindered translocation by a food carcinogen C8-dG adduct in Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): modeling and dynamics studies.Distinct energetics and closing pathways for DNA polymerase beta with 8-oxoG template and different incoming nucleotides.Effect of N2-guanyl modifications on early steps in catalysis of polymerization by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W.UmuD(2) inhibits a non-covalent step during DinB-mediated template slippage on homopolymeric nucleotide runs.Comparison of the in vitro replication of the 7-(2-oxoheptyl)-1,N2-etheno-2'-deoxyguanosine and 1,N2-etheno-2'-deoxyguanosine lesions by Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4)Visualizing sequence-governed nucleotide selectivities and mutagenic consequences through a replicative cycle: processing of a bulky carcinogen N2-dG lesion in a Y-family DNA polymerase.DNA polymerase structure-based insight on the mutagenic properties of 8-oxoguanine.Translesion DNA Synthesis.The Werner syndrome protein limits the error-prone 8-oxo-dG lesion bypass activity of human DNA polymerase kappa.Quantitative analysis of the efficiency and mutagenic spectra of abasic lesion bypass catalyzed by human Y-family DNA polymerases.Single-Molecule Investigation of Response to Oxidative DNA Damage by a Y-Family DNA PolymeraseGenetic effects of oxidative DNA damages: comparative mutagenesis of the imidazole ring-opened formamidopyrimidines (Fapy lesions) and 8-oxo-purines in simian kidney cells.DNA polymerases provide a canon of strategies for translesion synthesis past oxidatively generated lesions.Translesion synthesis across 1,N2-ethenoguanine by human DNA polymerases.
P2860
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P2860
Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion
@nl
Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion.
@ast
Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion.
@en
type
label
Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion
@nl
Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion.
@ast
Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion.
@en
prefLabel
Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion
@nl
Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion.
@ast
Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion.
@en
P2093
P2860
P1433
P1476
Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion.
@en
P2093
Dinshaw J Patel
Lucy Malinina
Nicholas E Geacintov
Olga Rechkoblit
Suse Broyde
Vitaly Kuryavyi
Yuan Cheng
P2860
P356
10.1371/JOURNAL.PBIO.0040011
P407
P577
2006-01-01T00:00:00Z