Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7
about
Structure and Ca²⁺-binding properties of the tandem C₂ domains of E-Syt2Synaptotagmin-1 and synaptotagmin-7 trigger synchronous and asynchronous phases of neurotransmitter releaseDistinct initial SNARE configurations underlying the diversity of exocytosisLateral diffusion of proteins on supported lipid bilayers: additive friction of synaptotagmin 7 C2A-C2B tandem domains.Cloning, expression, purification, crystallization and preliminary X-ray diffraction crystallographic study of human synaptotagmin 5 C2A domainSynaptotagmin-7 is an asynchronous calcium sensor for synaptic transmission in neurons expressing SNAP-23An Engineered Metal Sensor Tunes the Kinetics of Synaptic Transmission.Exocytosis and synaptic vesicle function.C2-domain containing calcium sensors in neuroendocrine secretion.Antioxidant, pro-oxidant and cytotoxic properties of parsley.Differential Membrane Binding Mechanics of Synaptotagmin Isoforms Observed in Atomic Detail.A synaptotagmin suppressor screen indicates SNARE binding controls the timing and Ca2+ cooperativity of vesicle fusion.Pull-down combined with proteomic strategy reveals functional diversity of synaptotagmin IExceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release.The synaptotagmin C2B domain calcium-binding loops modulate the rate of fusion pore expansion.
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P2860
Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7
description
2010 nî lūn-bûn
@nan
2010 թուականին հրատարակուած գիտական յօդուած
@hyw
2010 թվականին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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name
Structural and mutational anal ...... etween synaptotagmins-1 and -7
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Structural and mutational anal ...... etween synaptotagmins-1 and -7
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Structural and mutational anal ...... etween synaptotagmins-1 and -7
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Structural and mutational anal ...... etween synaptotagmins-1 and -7
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Structural and mutational anal ...... etween synaptotagmins-1 and -7
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Structural and mutational anal ...... etween synaptotagmins-1 and -7
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Structural and Mutational Anal ...... etween Synaptotagmins-1 and -7
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Structural and mutational anal ...... etween synaptotagmins-1 and -7
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Structural and mutational anal ...... etween synaptotagmins-1 and -7
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Structural and mutational anal ...... etween synaptotagmins-1 and -7
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Structural and mutational anal ...... etween synaptotagmins-1 and -7
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10.1371/JOURNAL.PONE.0012544
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P577
2010-01-01T00:00:00Z