Genetics and biology of pancreatic ductal adenocarcinoma - Test2 - elhamkhani - TriplyDB

Genetics and biology of pancreatic ductal adenocarcinoma

Genetics and biology of pancreatic ductal adenocarcinoma

http://www.wikidata.org/entity/Q26765438

about

Haploinsufficient tumor suppressor genes.Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer A novel method for RNA extraction from FFPE samples reveals significant differences in biomarker expression between orthotopic and subcutaneous pancreatic cancer patient-derived xenografts.Chidamide Inhibits Aerobic Metabolism to Induce Pancreatic Cancer Cell Growth Arrest by Promoting Mcl-1 Degradation LSL-KrasG12D; LSL-Trp53R172H/+; Ink4flox/+; Ptf1/p48-Cre mice are an applicable model for locally invasive and metastatic pancreatic cancer.MicroRNA-1291 targets the FOXA2-AGR2 pathway to suppress pancreatic cancer cell proliferation and tumorigenesis Mitochondrial mutations and metabolic adaptation in pancreatic cancer.Stromal cues regulate the pancreatic cancer epigenome and metabolome.ITGA1 is a pre-malignant biomarker that promotes therapy resistance and metastatic potential in pancreatic cancer.Dermokine contributes to epithelial-mesenchymal transition through increased activation of signal transducer and activator of transcription 3 in pancreatic cancer.Evaluation of neurotensin receptor 1 as a potential imaging target in pancreatic ductal adenocarcinoma.Roles of autophagy and metabolism in pancreatic cancer cell adaptation to environmental challenges.GOT1-mediated anaplerotic glutamine metabolism regulates chronic acidosis stress in pancreatic cancer cells.Proteome-Wide Protein Expression Profiling Across Five Pancreatic Cell Lines.Combinatorial Screening of Pancreatic Adenocarcinoma Reveals Sensitivity to Drug Combinations Including Bromodomain Inhibitor Plus Neddylation Inhibitor.MiR-143 Targeting TAK1 Attenuates Pancreatic Ductal Adenocarcinoma Progression via MAPK and NF-κB Pathway In Vitro.Expression of HMGB2 indicates worse survival of patients and is required for the maintenance of Warburg effect in pancreatic cancer.IL-33 acts as a foe to MIA PaCa-2 pancreatic cancer.Challenges and Opportunities in Modeling Pancreatic Cancer.Leveraging Mechanisms Governing Pancreatic Tumorigenesis To Reduce Pancreatic Cancer Mortality.Energy sources identify metabolic phenotypes in pancreatic cancer.The Heterocellular Emergence of Colorectal Cancer Alternating pH landscapes shape epithelial cancer initiation and progression: Focus on pancreatic cancer.Unique metabolic features of pancreatic cancer stroma: relevance to the tumor compartment, prognosis, and invasive potential.Detection of mutant KRAS and TP53 DNA in circulating exosomes from healthy individuals and patients with pancreatic cancer.BRSK2 induced by nutrient deprivation promotes Akt activity in pancreatic cancer via downregulation of mTOR activity.Tumor engraftment in patient-derived xenografts of pancreatic ductal adenocarcinoma is associated with adverse clinicopathological features and poor survival.EMT and Treatment Resistance in Pancreatic Cancer.Necroptosis DAMPens anti-tumor immunity GRP78 haploinsufficiency suppresses acinar-to-ductal metaplasia, signaling, and mutant Kras-driven pancreatic tumorigenesis in mice.Lymph node metastases in resected pancreatic ductal adenocarcinoma: predictors of disease recurrence and survival.Insulin Receptor and GPCR Crosstalk Stimulates YAP via PI3K and PKD in Pancreatic Cancer Cells.KRAS, YAP, and obesity in pancreatic cancer: A signaling network with multiple loops.Atypical flat lesions derive from pancreatic acinar cells.PDAC-derived exosomes enrich the microenvironment in MDSCs in a SMAD4-dependent manner through a new calcium related axis.Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer.Duct- and Acinar-Derived Pancreatic Ductal Adenocarcinomas Show Distinct Tumor Progression and Marker Expression.miR-92b-3p acts as a tumor suppressor by targeting Gabra3 in pancreatic cancer.Epithelial-Myeloid cell crosstalk regulates acinar cell plasticity and pancreatic remodeling in mice.

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Genetics and biology of pancreatic ductal adenocarcinoma

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2016 nî lūn-bûn

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2016 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2016 թվականի փետրվարին հրատարակված գիտական հոդված

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2016年の論文

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2016年學術文章

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Genetics and biology of pancreatic ductal adenocarcinoma

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Genetics and biology of pancreatic ductal adenocarcinoma

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Genetics and biology of pancreatic ductal adenocarcinoma

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Genetics and biology of pancreatic ductal adenocarcinoma

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Genetics and biology of pancreatic ductal adenocarcinoma

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Genetics and biology of pancreatic ductal adenocarcinoma

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Genetics and biology of pancreatic ductal adenocarcinoma

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Genetics and biology of pancreatic ductal adenocarcinoma

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Genetics and biology of pancreatic ductal adenocarcinoma

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Genes & Development

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Genetics and biology of pancreatic ductal adenocarcinoma

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Alec C Kimmelman

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Anirban Maitra

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Giulio F Draetta

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Haoqiang Ying

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Prasenjit Dey

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Ronald A DePinho

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Wantong Yao

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P2860

Hallmarks of Cancer: The Next Generation

Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling

Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice

Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis

Residual complexes containing SMARCA2 (BRM) underlie the oncogenic drive of SMARCA4 (BRG1) mutation

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

Understanding the Warburg effect: the metabolic requirements of cell proliferation

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

Links between metabolism and cancer

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1354016

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10.1101/GAD.275776.115

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4

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30

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