Mitochondrial disorders in children: toward development of small-molecule treatment strategies - Test2 - elhamkhani - TriplyDB

Mitochondrial disorders in children: toward development of small-molecule treatment strategies

Mitochondrial disorders in children: toward development of small-molecule treatment strategies

http://www.wikidata.org/entity/Q26767327

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Dynamics of Human Mitochondrial Complex I Assembly: Implications for Neurodegenerative Diseases Toward a therapy for mitochondrial disease Mitochondrial complex I inhibition triggers a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis in melanoma cells Autophagy enhanced the radioresistance of non-small cell lung cancer by regulating ROS level under hypoxia condition.Bromodomain Inhibitors Correct Bioenergetic Deficiency Caused by Mitochondrial Disease Complex I Mutations Post-Translational Oxidative Modifications of Mitochondrial Complex I (NADH: Ubiquinone Oxidoreductase): Implications for Pathogenesis and Therapeutics in Human Diseases.Therapeutic effects of the mitochondrial ROS-redox modulator KH176 in a mammalian model of Leigh Disease.Paradoxical Inhibition of Glycolysis by Pioglitazone Opposes the Mitochondriopathy Caused by AIF Deficiency.The Effects of Ascorbate, N-Acetylcysteine, and Resveratrol on Fibroblasts from Patients with Mitochondrial Disorders.Hypoxia therapy--a new hope for the treatment of mitochondrial dysfunctions.KH176 under development for rare mitochondrial disease: a first in man randomized controlled clinical trial in healthy male volunteers.Evaluation of mitochondrial bioenergetics, dynamics, endoplasmic reticulum-mitochondria crosstalk, and reactive oxygen species in fibroblasts from patients with complex I deficiency.International Workshop:: Outcome measures and clinical trial readiness in primary mitochondrial myopathies in children and adults. Consensus recommendations. 16-18 November 2016, Rome, Italy.KH176 Safeguards Mitochondrial Diseased Cells from Redox Stress-Induced Cell Death by Interacting with the Thioredoxin System/Peroxiredoxin Enzyme Machinery.Revisiting mitochondrial diagnostic criteria in the new era of genomics.Neuronal Dysfunction Associated with Cholesterol Deregulation.WAH-1/AIF regulates mitochondrial oxidative phosphorylation in the nematode Caenorhabditis elegans.Apoptosis-Inducing Factor (AIF) in Physiology and Disease: The Tale of a Repented Natural Born Killer.Everyday Activities for Children with Mitochondrial Disorder: A Retrospective Chart Review.A disease-associated Aifm1 variant induces severe myopathy in knockin mice.Rescue from galactose-induced death of Leigh Syndrome patient cells by pyruvate and NAD

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Mitochondrial disorders in children: toward development of small-molecule treatment strategies

http://www.wikidata.org/entity/Q26767327

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2016 nî lūn-bûn

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2016 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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EMBO Molecular Medicine

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Mitochondrial disorders in chi ...... -molecule treatment strategies

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Cheuk-Wing Fung

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Jan Am Smeitink

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NDUFS6 mutations are a novel cause of lethal neonatal mitochondrial complex I deficiency

A case of severe hypermetabolism of nonthyroid origin with a defect in the maintenance of mitochondrial respiratory control: a correlated clinical, biochemical, and morphological study

Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis

Mitochondrial disease in adults: what's old and what's new?

Mitochondrial targets for pharmacological intervention in human disease

Idebenone and neuroprotection: antioxidant, pro-oxidant, or electron carrier?

Emerging concepts in the therapy of mitochondrial disease

Mitochondrial structure and function are disrupted by standard isolation methods

Molecular diagnosis in mitochondrial complex I deficiency using exome sequencing

Beneficial effects of creatine, CoQ10, and lipoic acid in mitochondrial disorders

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3185816

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10.15252/EMMM.201506131

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biomedical investigative technique

mitochondrial disease

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