Epigenetic treatment of solid tumours: a review of clinical trials - Test2 - elhamkhani - TriplyDB

Epigenetic treatment of solid tumours: a review of clinical trials

Epigenetic treatment of solid tumours: a review of clinical trials

http://www.wikidata.org/entity/Q26773803

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A clinical-molecular update on azanucleoside-based therapy for the treatment of hematologic cancers Epigenetic modulators as therapeutic targets in prostate cancer Genetic and Epigenetic Alterations in Bladder Cancer A theoretical study on predicted protein targets of apple polyphenols and possible mechanisms of chemoprevention in colorectal cancer Thymic Epithelial Tumors phenotype relies on miR-145-5p epigenetic regulation Combined deletion and DNA methylation result in silencing of FAM107A gene in laryngeal tumors Rap2B GTPase: structure, functions, and regulation.The histone deacetylase inhibitor trichostatin a decreases lymphangiogenesis by inducing apoptosis and cell cycle arrest via p21-dependent pathways Demethylation of MicroRNA-124a Genes Attenuated Proliferation of Rheumatoid Arthritis Derived Fibroblast-Like Synoviocytes and Synthesis of Tumor Necrosis Factor-α.Decreased expression of connective tissue growth factor in non-small cell lung cancer is associated with clinicopathological variables and can be restored by epigenetic modifiers.Isobolographic analysis demonstrates additive effect of cisplatin and HDIs combined treatment augmenting their anti-cancer activity in lung cancer cell lines.Identification of Topological Network Modules in Perturbed Protein Interaction Networks.EMT- and MET-related processes in nonepithelial tumors: importance for disease progression, prognosis, and therapeutic opportunities.Drugging the pain epigenome.Aberrant DNA methylations in chondrosarcoma.Epigenetic modification in chromatin machinery and its deregulation in pediatric brain tumors: Insight into epigenetic therapies.Nuclear factor one transcription factors as epigenetic regulators in cancer.Effects of ionizing radiation on DNA methylation: from experimental biology to clinical applications.Immunomodulating and Immunoresistance Properties of Cancer-Initiating Cells: Implications for the Clinical Success of Immunotherapy.Epigenetic approach for angiostatic therapy: promising combinations for cancer treatment.Virus-host interplay in hepatitis B virus infection and epigenetic treatment strategies.How to stomach an epigenetic insult: the gastric cancer epigenome.Reolysin and Histone Deacetylase Inhibition in the Treatment of Head and Neck Squamous Cell Carcinoma.Targeting DNA hypermethylation: computational modeling of DNA demethylation treatment of acute myeloid leukemia.The transformation of the nuclear nanoarchitecture in human field carcinogenesis.Efficacy of EZH2 inhibitory drugs in human papillomavirus-positive and human papillomavirus-negative oropharyngeal squamous cell carcinomas.Anticancer Properties of Halogenated Pyrrolo[3,2-d]pyrimidines with Decreased Toxicity via N5 Substitution.Epigenetic Combination Therapy for Children With Secondary Myelodysplastic Syndrome (MDS)/Acute Myeloid Leukemia (AML) and Concurrent Solid Tumor Relapse.Role of proton-coupled folate transporter in pemetrexed resistance of mesothelioma: clinical evidence and new pharmacological tools.G protein-coupled receptor GPR55 promotes colorectal cancer and has opposing effects to cannabinoid receptor 1.Glioma CpG Island Methylator Phenotype (G-CIMP): Biological and Clinical Implications.Systems approach to the pharmacological actions of HDAC inhibitors reveals EP300 activities and convergent mechanisms of regulation in diabetes.HDAC inhibitor PAC-320 induces G2/M cell cycle arrest and apoptosis in human prostate cancer.Epigenetic regulation of HIV-1 latency: focus on polycomb group (PcG) proteins.Impact of DNA and RNA Methylation on Radiobiology and Cancer Progression.Image-based drug screen identifies HDAC inhibitors as novel Golgi disruptors synergizing with JQ1.The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma.Extensive and systematic rewiring of histone post-translational modifications in cancer model systems.DNA methylation as a marker of response in rheumatoid arthritis.An Interplay between Senescence, Apoptosis and Autophagy in Glioblastoma Multiforme-Role in Pathogenesis and Therapeutic Perspective.

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Epigenetic treatment of solid tumours: a review of clinical trials

http://www.wikidata.org/entity/Q26773803

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2015 nî lūn-bûn

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Epigenetic treatment of solid tumours: a review of clinical trials

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Epigenetic treatment of solid tumours: a review of clinical trials

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Epigenetic treatment of solid tumours: a review of clinical trials

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Epigenetic treatment of solid tumours: a review of clinical trials

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Epigenetic treatment of solid tumours: a review of clinical trials

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Epigenetic treatment of solid tumours: a review of clinical trials

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Epigenetic treatment of solid tumours: a review of clinical trials

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Epigenetic treatment of solid tumours: a review of clinical trials

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Epigenetic treatment of solid tumours: a review of clinical trials

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Clinical epigenetics

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Epigenetic treatment of solid tumours: a review of clinical trials

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Clara Nervi

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Elisabetta De Marinis

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Epigenetic gene silencing in cancer – a mechanism for early oncogenic pathway addiction?

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A phase I-II study of the histone deacetylase inhibitor valproic acid plus chemoimmunotherapy in patients with advanced melanoma

Histone acetylation and histone deacetylase activity of magnesium valproate in tumor and peripheral blood of patients with cervical cancer. A phase I study

Trials with 'epigenetic' drugs: an update

Perspectives on the mechanism of transcriptional regulation by long non-coding RNAs

Liquid biopsies: genotyping circulating tumor DNA

CpG-rich islands and the function of DNA methylation

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