Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications
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Inhibition of the fibroblast growth factor receptor (FGFR) pathway: the current landscape and barriers to clinical applicationA Versatile Tumor Gene Deletion System Reveals a Crucial Role for FGFR1 in Breast Cancer Metastasis.Safety, tolerability and pharmacokinetics of the fibroblast growth factor receptor inhibitor AZD4547 in Japanese patients with advanced solid tumours: a Phase I studyFibroblast growth factor receptors in breast cancer.Time-resolved FRET reports FGFR1 dimerization and formation of a complex with its effector PLCγ1.FGFR inhibitors: Effects on cancer cells, tumor microenvironment and whole-body homeostasis (Review).The Conundrum of Genetic "Drivers" in Benign Conditions.Regulation of brachyury by fibroblast growth factor receptor 1 in lung cancer.A novel non-ATP competitive FGFR1 inhibitor with therapeutic potential on gastric cancer through inhibition of cell proliferation, survival and migration.FGFs: crucial factors that regulate tumour initiation and progression.Mutation Detection of Fibroblast Growth Factor Receptor 3 for Infiltrative Hepatocellular Carcinoma by Whole-Exome Sequencing.Familial seborrhoeic keratosis associated with multiple "pure reticulated acanthomas" and infundibulocystic basal cell carcinomas.Landscape of activating cancer mutations in FGFR kinases and their differential responses to inhibitors in clinical use.A multiplex preclinical model for adenoid cystic carcinoma of the salivary gland identifies regorafenib as a potential therapeutic drug.FGFR inhibitor, AZD4547, impedes the stemness of mammary epithelial cells in the premalignant tissues of MMTV-ErbB2 transgenic miceA Phase 1 study of ARQ 087, an oral pan-FGFR inhibitor in patients with advanced solid tumours.Transcriptional signature of lymphoblastoid cell lines of BRCA1, BRCA2 and non-BRCA1/2 high risk breast cancer families.Unique signalling connectivity of FGFR3-TACC3 oncoprotein revealed by quantitative phosphoproteomics and differential network analysis.Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480.Muenke syndrome: An international multicenter natural history study.Design, synthesis and biological evaluation of 4-bromo-N-(3,5-dimethoxyphenyl)benzamide derivatives as novel FGFR1 inhibitors for treatment of non-small cell lung cancer.Fibroblast growth factor receptor 1 and 3 expression is associated with regulatory PI3K/AKT kinase activity, as well as invasion and prognosis, in human laryngeal cancer.Current Status of Fibroblast Growth Factor Receptor-Targeted Therapies in Breast Cancer
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P2860
Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications
description
2015 nî lūn-bûn
@nan
2015 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Fibroblast growth factor recep ...... ogic and clinical implications
@ast
Fibroblast growth factor recep ...... ogic and clinical implications
@en
Fibroblast growth factor recep ...... ogic and clinical implications
@nl
type
label
Fibroblast growth factor recep ...... ogic and clinical implications
@ast
Fibroblast growth factor recep ...... ogic and clinical implications
@en
Fibroblast growth factor recep ...... ogic and clinical implications
@nl
prefLabel
Fibroblast growth factor recep ...... ogic and clinical implications
@ast
Fibroblast growth factor recep ...... ogic and clinical implications
@en
Fibroblast growth factor recep ...... ogic and clinical implications
@nl
P2860
P921
P3181
P1476
Fibroblast growth factor recep ...... ogic and clinical implications
@en
P2093
Teresa Helsten
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P2888
P304
P3181
P356
10.1007/S10555-015-9579-8
P407
P5008
P577
2015-09-01T00:00:00Z
P5875
P6179
1032772638