Molecular pathways: fibroblast growth factor signaling: a new therapeutic opportunity in cancer
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Fibroblast growth factor receptor signaling as therapeutic targets in gastric cancerGenomic aberrations in the FGFR pathway: opportunities for targeted therapies in solid tumorsHedgehog is a positive regulator of FGF signalling during embryonic tracheal cell migrationThe 1.65 Å resolution structure of the complex of AZD4547 with the kinase domain of FGFR1 displays exquisite molecular recognitionDesign, synthesis and biological evaluation of novel FGFR inhibitors bearing an indazole scaffoldIdentification of targetable FGFR gene fusions in diverse cancers.The role of cancer-associated fibroblasts in esophageal cancerPhase I/IIa study evaluating the safety, efficacy, pharmacokinetics, and pharmacodynamics of lucitanib in advanced solid tumorsA Pan-Cancer Catalogue of Cancer Driver Protein Interaction InterfacesARS-interacting multi-functional protein 1 induces proliferation of human bone marrow-derived mesenchymal stem cells by accumulation of β-catenin via fibroblast growth factor receptor 2-mediated activation of AktFunctional role of adult hippocampal neurogenesis as a therapeutic strategy for mental disordersConformational transition of FGFR kinase activation revealed by site-specific unnatural amino acid reporter and single molecule FRET.The Role of FGFR1 Gene Amplification as a Poor Prognostic Factor in Squamous Cell Lung Cancer: A Meta-Analysis of Published DataData integration to prioritize drugs using genomics and curated data.Lymphovascular and neural regulation of metastasis: shared tumour signalling pathways and novel therapeutic approaches.miR-381-3p suppresses the proliferation of oral squamous cell carcinoma cells by directly targeting FGFR2.Interaction between the estrogen receptor and fibroblast growth factor receptor pathways in non-small cell lung cancerPrognostic significance of the co-overexpression of fibroblast growth factor receptors 1, 2 and 4 in gastric cancerIs fibroblast growth factor receptor 4 a suitable target of cancer therapy?A novel decoy receptor fusion protein for FGF-2 potently inhibits tumour growth.Role of postnatal expression of fgfr1 and fgfr2 in testicular germ cells on spermatogenesis and fertility in mice.Phase Ib study of dovitinib in combination with gemcitabine plus cisplatin or gemcitabine plus carboplatin in patients with advanced solid tumorsDiscovery of novel non-ATP competitive FGFR1 inhibitors and evaluation of their anti-tumor activity in non-small cell lung cancer in vitro and in vivo.Gene therapy in pancreatic cancer.A study on genetic variants of Fibroblast growth factor receptor 2 (FGFR2) and the risk of breast cancer from North IndiaProspective genetic profiling of squamous cell lung cancer and adenosquamous carcinoma in Japanese patients by multitarget assaysThe Fibroblast Growth Factor signaling pathwayDevelopment of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors.Fibroblast growth factor receptors in breast cancer.Antibody-mediated activation of FGFR1 induces FGF23 production and hypophosphatemia.Redundant kinase activation and resistance of EGFR-tyrosine kinase inhibitors.FGFR4 role in epithelial-mesenchymal transition and its therapeutic value in colorectal cancerMembrane-Type 1 Matrix Metalloproteinase Downregulates Fibroblast Growth Factor-2 Binding to the Cell Surface and Intracellular Signaling.Profiles of Basal and stimulated receptor signaling networks predict drug response in breast cancer lines.Mannose phosphate isomerase regulates fibroblast growth factor receptor family signaling and glioma radiosensitivity.A multiplexed, targeted mass spectrometry assay of the S100 protein family uncovers the isoform-specific expression in thyroid tumours.Mode of action of nintedanib in the treatment of idiopathic pulmonary fibrosisGenetic variants in the fibroblast growth factor pathway as potential markers of ovarian cancer risk, therapeutic response, and clinical outcomeFibroblast Growth Factor Receptor 1 and Related Ligands in Small-Cell Lung CancerThe Effect of Mutations on Drug Sensitivity and Kinase Activity of Fibroblast Growth Factor Receptors: A Combined Experimental and Theoretical Study.
P2860
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P2860
Molecular pathways: fibroblast growth factor signaling: a new therapeutic opportunity in cancer
description
2012 nî lūn-bûn
@nan
2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Molecular pathways: fibroblast ...... rapeutic opportunity in cancer
@ast
Molecular pathways: fibroblast ...... rapeutic opportunity in cancer
@en
Molecular pathways: fibroblast ...... rapeutic opportunity in cancer
@nl
type
label
Molecular pathways: fibroblast ...... rapeutic opportunity in cancer
@ast
Molecular pathways: fibroblast ...... rapeutic opportunity in cancer
@en
Molecular pathways: fibroblast ...... rapeutic opportunity in cancer
@nl
prefLabel
Molecular pathways: fibroblast ...... rapeutic opportunity in cancer
@ast
Molecular pathways: fibroblast ...... rapeutic opportunity in cancer
@en
Molecular pathways: fibroblast ...... rapeutic opportunity in cancer
@nl
P2093
P3181
P1476
Molecular pathways: fibroblast ...... rapeutic opportunity in cancer
@en
P2093
A. N. Brooks
E. Kilgour
P. D. Smith
P304
P3181
P356
10.1158/1078-0432.CCR-11-0699
P407
P577
2012-04-01T00:00:00Z