A pathway from chromosome transfer to engineering resulting in human and mouse artificial chromosomes for a variety of applications to bio-medical challenges
about
Studies of Tumor Suppressor Genes via Chromosome EngineeringTo Know How a Gene Works, We Need to Redefine It First but then, More Importantly, to Let the Cell Itself Decide How to Transcribe and Process Its RNAsDevelopment of a novel HAC-based "gain of signal" quantitative assay for measuring chromosome instability (CIN) in cancer cellsContinuous long-term cytotoxicity monitoring in 3D spheroids of beetle luciferase-expressing hepatocytes by nondestructive bioluminescence measurement.Highly Efficient Transfer of Chromosomes to a Broad Range of Target Cells Using Chinese Hamster Ovary Cells Expressing Murine Leukemia Virus-Derived Envelope ProteinsMoving toward a higher efficiency of microcell-mediated chromosome transferMultiple expression cassette exchange via TP901-1, R4, and Bxb1 integrase systems on a mouse artificial chromosomeMonochromosomal Hybrids and Chromosome Transfer: A Functional Approach for Gene Identification.Transformation-associated recombination (TAR) cloning for genomics studies and synthetic biology.Using human artificial chromosomes to study centromere assembly and function.A kidney injury molecule-1 (Kim-1) gene reporter in a mouse artificial chromosome: the responsiveness to cisplatin toxicity in immortalized mouse kidney S3 cells.Development of a Safeguard System Using an Episomal Mammalian Artificial Chromosome for Gene and Cell Therapy.Transfer of a Mouse Artificial Chromosome into Spermatogonial Stem Cells Generates Transchromosomic Mice.CRISPR/Cas9-induced transgene insertion and telomere-associated truncation of a single human chromosome for chromosome engineering in CHO and A9 cells.Evaluation of an Hprt-Luciferase Reporter Gene on a Mammalian Artificial Chromosome in Response to Cytotoxicity.Small chromosomal regions position themselves autonomously according to their chromatin class.Reversible immortalisation enables genetic correction of human muscle progenitors and engineering of next-generation human artificial chromosomes for Duchenne muscular dystrophy.Efficient derivation and inducible differentiation of expandable skeletal myogenic cells from human ES and patient-specific iPS cells.Establishment of a novel hepatocyte model that expresses four cytochrome P450 genes stably via mammalian-derived artificial chromosome for pharmacokinetics and toxicity studies.Aneuploidy: an important model system to understand salient aspects of functional genomics.Combinations of chromosome transfer and genome editing for the development of cell/animal models of human disease and humanized animal models.Development of a multiple-gene-loading method by combining multi-integration system-equipped mouse artificial chromosome vector and CRISPR-Cas9.Generation of a Synthetic Human Chromosome with Two Centromeric Domains for Advanced Epigenetic Engineering Studies.Human Artificial Chromosome with Regulated Centromere: A Tool for Genome and Cancer Studies
P2860
Q26771240-A1E0D28D-6023-4E58-88A6-BC45B0BBEE9CQ26774954-6530CC14-A25B-4C0A-B104-8EE4573EA55EQ28828588-14A6E96A-8659-4D7E-8157-1EA239BD35D1Q33823568-CD74718F-920E-4705-91F8-6495E65AC330Q36043396-7397AFBE-65E5-4D79-B7B2-C03D83CEEC96Q37028651-B67BD6E7-4BF2-476D-B385-293541FEADBEQ37681644-60EE0170-C214-49ED-804A-3FA0EE51B37FQ38708551-34B144D4-3B3D-4C3A-875A-B23C477FCB66Q38817999-1E6C69DD-DA70-45F3-A393-4214576C8739Q39422214-C9C5E763-2E8A-4BD7-B403-3EEC25C07439Q40505688-343DCDF1-4820-4CF3-A0DB-C57FBE0A8AA9Q41035760-443D6BFC-59B9-4AC4-83C0-E6ECE7ABF371Q41931083-CCA8C053-DA71-45F5-8DC9-FF9C402D8747Q42371790-F7225781-F920-4B5C-A3C0-480BCBA6AB9FQ42381661-75158455-AA9C-48CF-A2BC-06C9C7EB52D4Q45054543-B54FCB60-1C7D-4B99-8894-FB51B6D26420Q45875854-4C20323B-580B-49D9-B126-F4B068BF4053Q45876520-FEC53270-E779-4FC8-B590-03EB9F57F38FQ47161371-D4A7DC66-ECDB-4126-969D-964560D497F6Q47307659-F6D73201-D0EA-4146-832B-7F4ACE926D8FQ47309313-AD1A4681-3043-4883-8BAF-08C8BDEA359EQ52430591-4EF3B318-08A5-4A22-9B3B-1044626F9288Q52724970-08417198-095A-4A2E-86D0-2A60AF6F1E92Q58800824-B16D2621-19BC-4A76-A2F5-24612AD3EE52
P2860
A pathway from chromosome transfer to engineering resulting in human and mouse artificial chromosomes for a variety of applications to bio-medical challenges
description
2015 nî lūn-bûn
@nan
2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
A pathway from chromosome tran ...... ions to bio-medical challenges
@ast
A pathway from chromosome tran ...... ions to bio-medical challenges
@en
A pathway from chromosome tran ...... ions to bio-medical challenges
@nl
type
label
A pathway from chromosome tran ...... ions to bio-medical challenges
@ast
A pathway from chromosome tran ...... ions to bio-medical challenges
@en
A pathway from chromosome tran ...... ions to bio-medical challenges
@nl
prefLabel
A pathway from chromosome tran ...... ions to bio-medical challenges
@ast
A pathway from chromosome tran ...... ions to bio-medical challenges
@en
A pathway from chromosome tran ...... ions to bio-medical challenges
@nl
P2093
P2860
P921
P3181
P1433
P1476
A pathway from chromosome tran ...... ions to bio-medical challenges
@en
P2093
Mitsuo Oshimura
Motonobu Katoh
Narumi Uno
Toshiaki Inoue
Yasuhiro Kazuki
P2860
P2888
P304
P3181
P356
10.1007/S10577-014-9459-Z
P407
P577
2015-02-01T00:00:00Z
P5875
P6179
1026405867