Shift in brain metabolism in late onset Alzheimer's disease: implications for biomarkers and therapeutic interventions - Test2 - elhamkhani - TriplyDB

Shift in brain metabolism in late onset Alzheimer's disease: implications for biomarkers and therapeutic interventions

Shift in brain metabolism in late onset Alzheimer's disease: implications for biomarkers and therapeutic interventions

http://www.wikidata.org/entity/Q26830740

about

Menopause, obesity and inflammation: interactive risk factors for Alzheimer's disease Integrating transcriptomics with metabolic modeling predicts biomarkers and drug targets for Alzheimer's disease Ketogenic diet improves motor performance but not cognition in two mouse models of Alzheimer's pathology Neuroprotective Effects of Icariin on Brain Metabolism, Mitochondrial Functions, and Cognition in Triple-Transgenic Alzheimer's Disease Mice.Estrogen: a master regulator of bioenergetic systems in the brain and body APOE and neuroenergetics: an emerging paradigm in Alzheimer's disease.Huperzine A: Is it an Effective Disease-Modifying Drug for Alzheimer's Disease?Ovariectomy induces a shift in fuel availability and metabolism in the hippocampus of the female transgenic model of familial Alzheimer's.Regulation of substrate utilization by the mitochondrial pyruvate carrier Identification of altered metabolic pathways in plasma and CSF in mild cognitive impairment and Alzheimer's disease using metabolomics.The perimenopausal aging transition in the female rat brain: decline in bioenergetic systems and synaptic plasticity Bioenergetic mechanisms in astrocytes may contribute to amyloid plaque deposition and toxicity.Considerations in the design of clinical trials for cognitive aging.Minireview: translational animal models of human menopause: challenges and emerging opportunities.Regional Reproducibility of BOLD Calibration Parameter M, OEF and Resting-State CMRO2 Measurements with QUO2 MRI White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's Disease.Age-dependent roles of peroxisomes in the hippocampus of a transgenic mouse model of Alzheimer's disease.Graded perturbations of metabolism in multiple regions of human brain in Alzheimer's disease: Snapshot of a pervasive metabolic disorder Age, APOE and sex: Triad of risk of Alzheimer's disease.Identifying postmenopausal women at risk for cognitive decline within a healthy cohort using a panel of clinical metabolic indicators: potential for detecting an at-Alzheimer's risk metabolic phenotype Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention.Change in brain and lesion volumes after CEE therapies: the WHIMS-MRI studies Impairment of proteostasis network in Down syndrome prior to the development of Alzheimer's disease neuropathology: redox proteomics analysis of human brain.Estrogen regulation of mitochondrial bioenergetics: implications for prevention of Alzheimer's disease.Neurosteroids as regenerative agents in the brain: therapeutic implications.Role of astrocytic glycolytic metabolism in Alzheimer's disease pathogenesis.Perimenopause as a neurological transition state.Neuroketotherapeutics: A modern review of a century-old therapy.Metabolic and Inflammatory Adaptation of Reactive Astrocytes: Role of PPARs.Oxidation and ubiquitination in neurodegeneration.Exploring the Association between Alzheimer's Disease, Oral Health, Microbial Endocrinology and Nutrition.Insulin Resistance and Alzheimer's Disease: Bioenergetic Linkages.Mitochondrial Bioenergetics Is Altered in Fibroblasts from Patients with Sporadic Alzheimer's Disease.JNK: A Putative Link Between Insulin Signaling and VGLUT1 in Alzheimer's Disease.Application of Metabolomics in Alzheimer's Disease.The Role of Stress-Induced O-GlcNAc Protein Modification in the Regulation of Membrane Transport.

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Shift in brain metabolism in late onset Alzheimer's disease: implications for biomarkers and therapeutic interventions

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2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2011 թվականի օգոստոսին հրատարակված գիտական հոդված

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2011年の論文

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Shift in brain metabolism in l ...... and therapeutic interventions

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Shift in brain metabolism in l ...... and therapeutic interventions

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J.MAM.2011.10.005

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Molecular Aspects of Medicine

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Shift in brain metabolism in l ...... and therapeutic interventions

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Enrique Cadenas

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Jamaica R. Rettberg

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Jia Yao

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Lauren P. Klosinski

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Roberta Diaz Brinton

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Diagnosis-independent Alzheimer disease biomarker signature in cognitively normal elderly people

Cytochrome c oxidase and mitochondrial F1F0-ATPase (ATP synthase) activities in platelets and brain from patients with Alzheimer's disease

Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

In vivo imaging of amyloid deposition in Alzheimer disease using the radioligand 18F-AV-45 (florbetapir [corrected] F 18)

Spatial correlation between brain aerobic glycolysis and amyloid-β (Aβ ) deposition

Regional aerobic glycolysis in the human brain

11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

2-Deoxy-D-glucose treatment induces ketogenesis, sustains mitochondrial function, and reduces pathology in female mouse model of Alzheimer's disease

Fatty acid oxidation and ketogenesis by astrocytes in primary culture

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Alzheimer's disease

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