The Mediator complex: a central integrator of transcription - Test2 - elhamkhani - TriplyDB

The Mediator complex: a central integrator of transcription

The Mediator complex: a central integrator of transcription

http://www.wikidata.org/entity/Q26849595

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Importance of Mediator complex in the regulation and integration of diverse signaling pathways in plants TRIM28 as a novel transcriptional elongation factor Mediator kinase module and human tumorigenesis Getting up to speed with transcription elongation by RNA polymerase II Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19 Disorders of Transcriptional Regulation: An Emerging Category of Multiple Malformation Syndromes The diverse and expanding role of mass spectrometry in structural and molecular biology Mediator kinase inhibition further activates super-enhancer-associated genes in AML Assessing the mechanism and therapeutic potential of modulators of the human Mediator complex-associated protein kinases H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-β-Catenin Signaling in Colorectal Cancer.Controlling the Master: Chromatin Dynamics at the MYC Promoter Integrate Developmental Signaling Enhancers and chromatin structures: regulatory hubs in gene expression and diseases.The nematode homologue of Mediator complex subunit 28, F28F8.5, is a critical regulator of C. elegans development.A Kinase-Independent Role for Cyclin-Dependent Kinase 19 in p53 Response.Proteomic Analysis of the Mediator Complex Interactome in Saccharomyces cerevisiae Linking Core Promoter Classes to Circadian Transcription Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice.Cyclin-Dependent Kinase Inhibitors as Anticancer Therapeutics Most of the tight positional conservation of transcription factor binding sites near the transcription start site reflects their co-localization within regulatory modules.A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease.The Mediator Subunit MED16 Transduces NRF2-Activating Signals into Antioxidant Gene Expression.A MED13-dependent skeletal muscle gene program controls systemic glucose homeostasis and hepatic metabolism.Type I interferon inhibits varicella-zoster virus replication by interfering with the dynamic interaction between mediator and IE62 within replication compartments.Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombination BET Bromodomain Inhibition Releases the Mediator Complex from Select cis-Regulatory Elements.Noncoding RNAs: Regulators of the Mammalian Transcription Machinery.Promoter-enhancer looping at the PPARγ2 locus during adipogenic differentiation requires the Prmt5 methyltransferase.Chromatin structure and gene regulation: a dynamic view of enhancer function Evidence for Multiple Mediator Complexes in Yeast Independently Recruited by Activated Heat Shock Factor.Auxin-dependent compositional change in Mediator in ARF7- and ARF19-mediated transcription.Defining the essential function of FBP/KSRP proteins: Drosophila Psi interacts with the mediator complex to modulate MYC transcription and tissue growth Comprehensive analysis of the transcriptional profile of the Mediator complex across human cancer types.Chromatin architecture underpinning transcription elongation Regulation of metabolism by the Mediator complex.MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis.Mediator Complex Subunit MED1 Protein Expression Is Decreased during Bladder Cancer Progression.Search for Master Regulators in Walking Cancer Pathways.MED12 regulates a transcriptional network of calcium-handling genes in the heart.Med15B Regulates Acid Stress Response and Tolerance in Candida glabrata by Altering Membrane Lipid Composition.ETV4 and AP1 Transcription Factors Form Multivalent Interactions with three Sites on the MED25 Activator-Interacting Domain.

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The Mediator complex: a central integrator of transcription

http://www.wikidata.org/entity/Q26849595

description

2015 nî lūn-bûn

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2015 թուականի Մարտին հրատարակուած գիտական յօդուած

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2015 թվականի մարտին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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The Mediator complex: a central integrator of transcription

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The Mediator complex: a central integrator of transcription

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Nature Reviews Molecular Cell Biology

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The Mediator complex: a central integrator of transcription

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Benjamin L. Allen

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Dylan J. Taatjes

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P2860

Classification of intrinsically disordered regions and proteins

An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis

HIF1A employs CDK8-mediator to stimulate RNAPII elongation in response to hypoxia

Activation of TRAP/mediator subunit TRAP220/Med1 is regulated by mitogen-activated protein kinase-dependent phosphorylation

Subunit architecture and functional modular rearrangements of the transcriptional mediator complex

MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling

Human mediator subunit MED26 functions as a docking site for transcription elongation factors

Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex

Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways

MED1 phosphorylation promotes its association with mediator: implications for nuclear receptor signaling

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10.1038/NRM3951

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4963239

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