O(6)-methylguanine-DNA methyltransferase in glioma therapy: promise and problems - Test2 - elhamkhani - TriplyDB

O(6)-methylguanine-DNA methyltransferase in glioma therapy: promise and problems

O(6)-methylguanine-DNA methyltransferase in glioma therapy: promise and problems

http://www.wikidata.org/entity/Q26853112

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Toward a Molecular Classification of Colorectal Cancer: The Role of MGMT Case comparison and literature review of glioblastoma: A tale of two tumors Epigenetics in Cancer: A Hematological Perspective Therapeutic efficacy of aldoxorubicin in an intracranial xenograft mouse model of human glioblastoma.Redox-responsive magnetic nanoparticle for targeted convection-enhanced delivery of O6-benzylguanine to brain tumors Early assessment of the efficacy of temozolomide chemotherapy in experimental glioblastoma using [18F]FLT-PET imaging.A Phase III study of radiation therapy (RT) and O⁶-benzylguanine + BCNU versus RT and BCNU alone and methylation status in newly diagnosed glioblastoma and gliosarcoma: Southwest Oncology Group (SWOG) study S0001.Phase I/randomized phase II study of afatinib, an irreversible ErbB family blocker, with or without protracted temozolomide in adults with recurrent glioblastoma.Chemotherapy with BCNU in recurrent glioma: Analysis of clinical outcome and side effects in chemotherapy-naïve patients.Chemotherapeutic effect of a novel temozolomide analog on nasopharyngeal carcinoma in vitro and in vivo.Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host Increased age of transformed mouse neural progenitor/stem cells recapitulates age-dependent clinical features of human glioma malignancy.Repair of 3-methyladenine and abasic sites by base excision repair mediates glioblastoma resistance to temozolomide ELTD1, a potential new biomarker for gliomas.Tumor Suppressor WWOX and p53 Alterations and Drug Resistance in Glioblastomas.Therapeutic effect of TMZ-POH on human nasopharyngeal carcinoma depends on reactive oxygen species accumulation.Detection of MGMT, RASSF1A, p15INK4B, and p14ARF promoter methylation in circulating tumor-derived DNA of central nervous system cancer patients Disrupting the CXCL12/CXCR4 axis disturbs the characteristics of glioblastoma stem-like cells of rat RG2 glioblastoma.Enzastaurin before and concomitant with radiation therapy, followed by enzastaurin maintenance therapy, in patients with newly diagnosed glioblastoma without MGMT promoter hypermethylation.Experimental validation of 5 in-silico predicted glioma biomarkers.Influence of promoter/enhancer region haplotypes on MGMT transcriptional regulation: a potential biomarker for human sensitivity to alkylating agents.ReACT Phase II trial: a critical evaluation of the use of rindopepimut plus bevacizumab to treat EGFRvIII-positive recurrent glioblastoma.pH-Sensitive O6-Benzylguanosine Polymer Modified Magnetic Nanoparticles for Treatment of Glioblastomas.Murine cell line model of proneural glioma for evaluation of anti-tumor therapies Optimizing glioblastoma temozolomide chemotherapy employing lentiviral-based anti-MGMT shRNA technology Experimental study of a novel tumstatin on C6 brain glioma in vitro.Integrins and p53 pathways in glioblastoma resistance to temozolomide.O(6)-methylguanine-DNA methyltransferase activity is associated with response to alkylating agent therapy and with MGMT promoter methylation in glioblastoma and anaplastic glioma.Comparative Aspects of Molecular Mechanisms of Drug Resistance through ABC Transporters and Other Related Molecules in Canine Lymphoma.Culture on 3D Chitosan-Hyaluronic Acid Scaffolds Enhances Stem Cell Marker Expression and Drug Resistance in Human Glioblastoma Cancer Stem Cells.Prioritizing uncharacterized genes in the search for glioma biomarkers.A systematic review and meta-analysis: Association between MGMT hypermethylation and the clinicopathological characteristics of non-small-cell lung carcinoma.The Role of DNA Methylation in Cancer.

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O(6)-methylguanine-DNA methyltransferase in glioma therapy: promise and problems

http://www.wikidata.org/entity/Q26853112

description

2012 nî lūn-bûn

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2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի օգոստոսին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

O(6)-methylguanine-DNA methyltransferase in glioma therapy: promise and problems

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O(6)-methylguanine-DNA methyltransferase in glioma therapy: promise and problems

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O(6)-methylguanine-DNA methyltransferase in glioma therapy: promise and problems

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label

O(6)-methylguanine-DNA methyltransferase in glioma therapy: promise and problems

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O(6)-methylguanine-DNA methyltransferase in glioma therapy: promise and problems

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O(6)-methylguanine-DNA methyltransferase in glioma therapy: promise and problems

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O(6)-methylguanine-DNA methyltransferase in glioma therapy: promise and problems

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O(6)-methylguanine-DNA methyltransferase in glioma therapy: promise and problems

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O(6)-methylguanine-DNA methyltransferase in glioma therapy: promise and problems

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J.BBCAN.2011.12.004

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Biochimica et Biophysica Acta

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O(6)-methylguanine-DNA methyltransferase in glioma therapy: promise and problems

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A. Blank

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John R. Silber

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Marc C. Chamberlain

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Michael S. Bobola

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P2860

DNA resection in eukaryotes: deciding how to fix the break

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.

MGMT gene silencing and benefit from temozolomide in glioblastoma.

MGMT promoter methylation is prognostic but not predictive for outcome to adjuvant PCV chemotherapy in anaplastic oligodendroglial tumors: a report from EORTC Brain Tumor Group Study 26951.

CpG islands in vertebrate genomes

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

Epigenetics in cancer

Epidemiology of primary brain tumors: current concepts and review of the literature.

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